This Letter reports on the first measurements of transverse momentum dependent flow angle Ψn and
flow magnitude vn fluctuations, determined using new four-particle correlators. The measurements
are ...performed for various centralities in Pb–Pb collisions at a centre-of-mass energy per nucleon
pair of √sNN = 5.02 TeV with ALICE at the CERN Large Hadron Collider. Both flow angle and
flow magnitude fluctuations are observed in the presented centrality ranges and are strongest in the
most central collisions and for a transverse momentum pT > 2 GeV/c. Comparison with theoretical
models, including iEBE-VISHNU, MUSIC, and AMPT, show that the measurements exhibit unique
sensitivities to the initial state of heavy-ion collisions.
This letter reports measurements which characterize the underlying event associated with hard scatterings at mid-pseudorapidity (|$η$| < 0.8) in pp, p–Pb and Pb–Pb collisions at centre-of-mass energy ...per nucleon pair, $\sqrt{s_{NN}}=5.02$ TeV. The measurements are performed with ALICE at the LHC. Different multiplicity classes are defined based on the event activity measured at forward rapidities. The hard scatterings are identified by the leading particle defined as the charged particle with the largest transverse momentum ($p_{T}$) in the collision and having 8 < $p_{T}$ < 15 GeV/c. The $p_{T}$ spectra of associated particles (0.5 < $p_{T}$ < 6 GeV/c) are measured in different azimuthal regions defined with respect to the leading particle direction: toward, transverse, and away. The associated charged particle yields in the transverse region are subtracted from those of the away and toward regions. The remaining jet-like yields are reported as a function of the multiplicity measured in the transverse region. The measurements show a suppression of the jet-like yield in the away region and an enhancement of high-$p_{T}$ associated particles in the toward region in central Pb–Pb collisions, as compared to minimum-bias pp collisions. These observations are consistent with previous measurements that used two-particle correlations, and with an interpretation in terms of parton energy loss in a high-density quark gluon plasma. These yield modifications vanish in peripheral Pb–Pb collisions and are not observed in either high-multiplicity pp or p–Pb collisions.
This letter reports measurements which characterize the underlying event associated with hard scatterings at mid-pseudorapidity (|$η$| < 0.8) in pp, p–Pb and Pb–Pb collisions at centre-of-mass energy ...per nucleon pair, $\sqrt{s_{NN}}=5.02$ TeV. The measurements are performed with ALICE at the LHC. Different multiplicity classes are defined based on the event activity measured at forward rapidities. The hard scatterings are identified by the leading particle defined as the charged particle with the largest transverse momentum ($p_{T}$) in the collision and having 8 < $p_{T}$ < 15 GeV/c. The $p_{T}$ spectra of associated particles (0.5 < $p_{T}$ < 6 GeV/c) are measured in different azimuthal regions defined with respect to the leading particle direction: toward, transverse, and away. The associated charged particle yields in the transverse region are subtracted from those of the away and toward regions. The remaining jet-like yields are reported as a function of the multiplicity measured in the transverse region. The measurements show a suppression of the jet-like yield in the away region and an enhancement of high-$p_{T}$ associated particles in the toward region in central Pb–Pb collisions, as compared to minimum-bias pp collisions. These observations are consistent with previous measurements that used two-particle correlations, and with an interpretation in terms of parton energy loss in a high-density quark gluon plasma. These yield modifications vanish in peripheral Pb–Pb collisions and are not observed in either high-multiplicity pp or p–Pb collisions.
Aim: To determine whether DNA ploidy by image cytometry is a good diagnostic tool to distinguish benign and malignant salivary gland tumours.
Methods: A total of 62 salivary gland tumours were ...studied. Cases were histologically diagnosed haematoxylin and eosin (H&E). According to the World Health Organization (WHO) classification, there were 14 mucoepidermoid carcinomas (MEC), 11 adenoid cystic carcinomas (ACC), 10 pleomorphic adenomas (PA), 10 carcinoma ex PA (CEPA), 9 acinic cell carcinomas (ACCa), 3 polymorphous low‐grade adenocarcinomas (PLGA), 2 papillary cystadenocarcinomas (PC), 1 myoepithelial carcinoma (MC), 1 undifferentiated carcinoma (UC) and 1 mucinous adenocarcinoma (MA). Paraffin sections (40 μm) were micro‐dissected to isolate tumour areas; cell nuclei were extracted and Feulgen‐stained cytospin monolayers were analysed using a DNA image cytometry system. For each case, DNA index (DI) was calculated relative to internal controls (lymphocytes; DI = 1.0). Cases were categorized as diploid or aneuploid and the proportion of cells over 5c was also calculated.
Results: Fifty‐three of 62 salivary gland tumours were uniformly diploid. Only nine cases were aneuploid: five CEPA, one low‐grade MEC, one PC, one UC and one MA.
Conclusions: The vast majority of salivary gland tumours were diploid. High‐grade malignancies may be aneuploid, and ploidy may be useful to identify malignant change in atypical PA. Further, larger studies are needed to confirm our results and to further evaluate the usefulness of the technique in high‐grade lesions.
Ultracompact X-ray binaries (UCXBs) are a distinctive but elusive family of low-mass X-ray binaries (LMXBs) characterised by their tight orbits and degenerate donor stars. Here we present ...UltraCompCAT, the first online and comprehensive catalogue of UCXBs. The initial version of UltraCompCAT comprises 49 sources, including 20 confirmed UCXBs (those with a measured orbital period shorter than 80 min) and 25 systems that we label ‘candidates’ based on their multi-wavelength phenomenology. For completeness, we also include four LMXBs with orbital periods in the range of 80 to 120 min, since they might be related to (e.g. close progenitors) or even part of the UCXB population that evolved towards longer periods. We discuss the orbital period and Galactic distribution of the catalogue sample. We provide evidence for the presence of at least two separate groups of UCXBs, one formed by persistent systems with orbital periods shorter than 30 min and a second group of transient objects (70 %) with periods in the range of 40 to 60 min. We show that the former group is dominated by sources formed in globular clusters, while the latter accounts for the (known) UCXB population in the Galactic field. We discuss the possible evolutionary channels for the two groups.