Este artículo aborda la representación de las identidades LGBTIQ+ adolescentes en las dos primeras temporadas de la serie ‘Sex Education’ (Netflix, 2019-). Partiendo de una metodología de análisis ...anclada en la Teoría Queer y en el concepto de interseccionalidad se estudiará la construcción de aquellos personajes cuya expresión de género y/u orientación sexual trascienden los límites establecidos por la cisheteronormatividad, además de aquellos cuyos deseos (heterocoincidentes o no) no encajan dentro de lo que las sociedades occidentales entienden como «normal», puesto que se parte del rechazo a la norma como elemento constitutivo de lo queer. Los objetivos principales se concretan en: a.) determinar qué imágenes, conocimientos y construcciones epistemológicas se difunden en la serie en torno a la diversidad sexogenérica; y b.) definir qué discurso articula la serie sobre (no)identidades queer y la violencia que sufren las personas LGBTIQ+.
Cerebellar neurons are generated from the rhombic lip and the neuroepithelium. In this study, we analyze the histogenesis of the cerebellar neuroepithelium in terms of cellular kinetics. The ...experimental animals are the offspring of pregnant dams injected with 5-bromo-2ʹ-deoxyuridine (BrdU) on embryonic day 13. We infer the fraction of S-phase cells by examining a range of survival times after a single BrdU-exposure and a cumulative BrdU-labeling sequence, which allow for the derivation of cell-cycle parameters and phase durations. The current results indicate that the dose of BrdU employed (35 mg/kg) provides saturation S-phase labeling from at least 1 h after marker delivery. The duration of G2, mitotic phase, and G1 are 1.2, 0.5, and 6.9 h, respectively. The duration for the S-phase, growth fraction, and the whole cycle are obtained on the basis of two proliferative models, steady-state and exponential growth. Both models provided similar results. In conclusion, our results indicate that the steady-state and the cumulative S-phase labeling paradigms can be adopted to analyze cell cycle parameters in the cerebellar neuroepithelium. Current results can help in understanding the regulatory mechanisms of cerebellar histogenesis and the cell biological mechanisms of the proliferative cycle of the neuroepithelium.
Ropivacaine has been described as a safer local anaesthetic (LA); however, serious cardiotoxic accidents have been reported. Intravenous‐lipid‐emulsion (ILE) therapy during LA intoxication seems to ...act as an antidote. Sodium bicarbonate is the standard treatment for sodium channel blocker drug toxicity. We compared both antidotes on the reversion of electrophysiologic toxicity induced by ropivacaine. Ropivacaine 5 mg kg−1 was administered in 24 pigs, and 3 min later, the animals received ILE: 1.5 ml kg−1 + 0.25 ml kg−1 min−1 (ILE group); sodium bicarbonate: 2 mEq kg−1 + 1 mEq kg−1 h−1 (NaHCO3 group); saline solution (CTL group). Electrophysiological parameters were evaluated for 30 min. The area under the curve (AUC) for the first 5 or 30 min was compared between groups. Ropivacaine induced a lengthening of the PR interval by 17% (P = 0.0001), His‐ventricle‐interval by 58% (P = 0.001), sinus QRS complex by 56% (P = 0.0001), paced QRS at 150 bpm by 257% (P = 0.0001), and at 120 bpm by 143% (P = 0.0001) in all groups. At 5 min after treatment, sinus QRS in the NaHCO3 group was shorter than that in the CTL group (AUCQRS5, P = 0.003) or ILE group (AUCQRS5, P = 0.045). During the first minute, seven of the animals in the NaHCO3 group vs. two in the ILE or 0 in the CTL group recovered more than 30% of the sinus QRS previously lengthened by ropivacaine (P = 0.003). Sodium bicarbonate reversed the electrophysiological toxicity of ropivacaine faster than ILE and control groups.
Patient empowerment is a component of the World Health Organization's multimodal strategy to improve hand hygiene (HH). Its successful implementation requires knowledge of the perceptions and ...attitudes of patients and health care workers (HCWs) toward patient empowerment in HH.
A cross-sectional study, through a self-administered questionnaire of patients and their families and HCWs, was conducted in a 433-bed block of an 850-bed university hospital in Galicia, Spain.
A total of 337 patients and their families and 196 HCWs completed the questionnaire. Among patients and their families, 49.9% were willing to remind HCWs about HH. However, only 31.6% of HCWs (41.8% of physicians and 24.8% of nurses) supported patient participation. The most common reason for patients and their families not being willing to ask caregivers to perform HH was fear of causing annoyance or receiving worse treatment as a consequence (76%). The main reasons that physicians disagreed with patient participation was patients’ lack of knowledge (40%) and possible negative effects on the HCW/patient relationship (40%). Nurses considered this participation unnecessary (58%).
There were significant differences between patients and their families and HCWs regarding support for patient empowerment in promoting HH. In our setting, a cultural change is needed in the HCW/patient relationship to create a facilitating environment.
Affiliation with certain groups allows to simultaneously satisfy two competing needs: the need to be moderately different from others and the need to belong. We propose that the feminist movement, ...that has been turning towards individualistic goals based on individual empowerment, may be one of such groups for women. In three studies we examined the relationship between self‐uniqueness and women's support for collective action and structural measures (i.e. sex quotas) promoted by the feminist movement. A first correlational study indicated that self‐uniqueness need is positively associated with willingness to participate in collective action for gender justice generally, but not with support for sex quotas. Consistently, two experimental studies (Studies 2–3) found that priming self‐uniqueness increases collective action intentions, but not quota support. Study 3 also showed that the effect of self‐uniqueness on collective action intentions for gender justice may be mediated by greater perceptions of personal discrimination for being a woman and fusion with the feminist movement. These results suggest that appeals to self‐uniqueness may attract women to the feminist movement but do not guarantee support for concrete collective measures against gender inequality.
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