This paper describes a fast and efficient procedure to separate and identify indole alkaloids from the ethanolic extract of Tabernaemontana fuchsiaefolia (Apocynaceae). The alkaloidal fractions ...obtained from ethanolic extracts of leaves and stem barks and root barks were fractioned and analyzed by Thin-Layer Chromatography (TLC) and by Gas Chromatography coupled to Mass Spectrometry (GC-MS). The following indole alkaloids were identified: ibogamine, coronaridine, ibogaine pseudoindoxyl, voacangine hydroxyindolenine, voacangine pseudoindoxyl, tabernanthine, catharanthine, voacangine, 19-oxovoacangine, 10-hydroxycoronaridine, affinisine, 16-epi-affinine, voachalotine, ibogaline, and conopharyngine.
Abstract
The methanol extract of Randia hebecarpa. Benth. (Rubiaceae) leaves was evaluated for anti-inflammatory activity using carrageenan- and dextran-induced rat paw edema models. Antioxidant ...activities of the methanol extract and of the fractions resulting from its partition were also measured using the 1,1-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay and the linoleic acid peroxidation method. The methanol extract, ethyl acetate fraction, and hydromethanol fraction exhibited percent inhibition of lipid peroxidation comparable to that of commercial antioxidant butylated hydroxytoluene (BHT). Fractionation of the ethyl acetate and hydromethanol fractions through chromatographic methods yielded kaempferol-3, 7-O.-α.-L-dirhamnoside, kaempferol-3-O.-β.-D-galactoside, quercetin-3-O.-β.-D-galactoside, myricetin-3-O.-α.-L-rhamnoside, kaempferol-3-O.-α.-L-rhamnosyl-(1 → 6)-β.-D-galactosyl-7-O.-α.-L-rhamnoside, quinovic acid-3-O.-β.-D-quinovopyranosil-28-O.-β.-D-glucopyranoside, cincholic acid 3-O.-β.-D-quinovopyranosil-28-O.-β.-D-glucopyranoside, and the sugar D-mannitol.
The chemical investigation of
Heliotropium transalpinum var.
transalpinum Vell. (Boraginaceae) led to the isolation of transalpinecine (
1), a novel pyrrolizidine alkaloid, in addition to known ...alkaloids subulacine (1β-2β-epoxy-1α-hydroxymethyl-8α-pyrrolizidine) (
2), and 1α-2α-epoxy-1β-hydroxymethyl-8α-pyrrolizidine (
3). The structures of the isolated compounds were elucidated based on spectroscopic data and theoretical calculations.
Lethality of the extracts of Croton floribundus (Euphorbiaceae), a medicinal plant from south Brazil, and of the kaurenoic acid, an isolated compound, and two of its derivatives against adult ...Biomphalaria glabrata snails, Schistosoma mansoni cercariae and Artemia salina Leach. brine shrimp larvae are reported. Both extracts and the isolated compound showed significant molluscicidal and cercaricidal activities and reduced toxicity in brine shrimp assays.
O estudo fitoquímico das folhas de Calycorectes psidiiflorus (O. Berg) Sobral, Myrtaceae, resultou no isolamento e identificação de: sesquiterpeno 8-hidroxicalameneno (1), triterpenos α-amirina (2a) ...e β-amirina (2b), flavonóide 3-O-α-ramnopiranosil-7-O-bglucopiranosil canferol (3), e alcalóide 1,2,3,4-tetraidro-1-metil-β-carbolina (4). As estruturas das substâncias isoladas foram elucidadas com base nos seus dados de RMN em comparação com os da literatura. A substância 8-hydroxicalameneno apresentou atividade antibacteriana (MIC = 7,8 µg/mL) e antifúngica (MIC = 15,6 µg/mL).
The antibacterial and antifungal properties of ethanolic extract of the leaves of
Pedilanthus tithymaloides and some of its constituents were investigated by the dilution method.
Iridoid glucosides from Bouchea fluminensis Schuquel, Ivânia T.Albrecht; Malheiros, Angela; Sarragiotto, Maria Helena ...
Phytochemistry (Oxford),
12/1998, Letnik:
49, Številka:
8
Journal Article
Recenzirano
From the aerial parts of
Bouchea fluminensis, a new iridoid glucoside, named boucheoside, along with four known iridoid glucosides, lamiide, lamiidoside, durantoside II, and duranterectoside C, were ...isolated. The structure of the new compound was elucidated based on the spectroscopic evidence.
Coumarins from Chaptalia integerrima (Asteraceae) Zottis, Aderson; José Vidotti, Gentil; Sarragiotto, Maria Helena
Biochemical systematics and ecology,
07/2001, Letnik:
29, Številka:
7
Journal Article
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