Two hundred bilateral temporal artery biopsies performed prospectively in 200 patients suspected of having giant cell arteritis (GCA) were always preceded by Doppler flow study and local clinical ...examination. If bilateral temporal artery biopsies had been guided by positive local clinical examination, 24 positive biopsies would have been found, and Doppler studies would have improved the diagnostic score to 39; however, the biopsies gave 42 histologically positive results, providing the best diagnostic yield. The possibility of GCA with normal Doppler flow studies was noted as well as the existence of relatively asymptomatic forms of GCA, so that systematic performance of bilateral temporal artery biopsy would seem justified in any case of suspected GCA.
We deal with a numerical solution of a scalar nonstationary convection-diffusion equation with a nonlinear convection and a linear diffusion terms. We carry out the space semi-discretization with the ...aid of the nonsymmetric interior penalty Galerkin (NIPG) method and the time discretization by a combination of implicit-explicit Runge-Kutta method. The resulting scheme is unconditionally stable, has a high order of accuracy with respect to space and time coordinates and requires solutions of linear algebraic problems at each time step. We derive a priori error estimates in the L2-norm.
Extranodal lymphomas which present in the nasal cavity and/or the paranasal sinuses are rare. Thirty‐eight patients with disease that was clinically limited to the head and neck (Ann Arbor Stages ...IE‐IIE) were admitted between 1947 and 1983. Twenty‐eight patients were treated with radiotherapy alone and 10 received combination chemotherapy in addition. The overall 5‐year survival figure was 56%. The corresponding result for Stage IE was 67%. No patient with Stage IIE disease survived 5 years. Extent of the extranodal disease also influenced results for Stage IE patients who were treated with radiotherapy only. When the extranodal disease was staged using the American Joint Committee TNM system, the 5‐year disease‐free survival for T1 and T2 patients was 78% as compared with 19% for patients with T3 and T4 disease. The addition of combination chemotherapy improved results for patients with T3 and T4 lesions.