Virtual reality (VR) and augmented reality (AR) are overcoming the physical limits of real‐life using advances in devices and software. In particular, the recent restrictions in transportation from ...the coronavirus disease 2019 (COVID‐19) pandemic are making people more interested in these virtual experiences. However, to minimize the differences between artificial and natural perception, more human‐interactive and human‐like devices are necessary. The skin is the largest organ of the human body and interacts with the environment as the site of interfacing and sensing. Recent progress in skin electronics has enabled the use of the skin as the mounting object of functional devices and the signal pathway bridging humans and computers, with opening its potential in future VR and AR applications. In this review, the current skin electronics are summarized as one of the most promising device solutions for future VR/AR devices, especially focusing on the recent materials and structures. After defining and explaining VR/AR systems and the components, the advantages of skin electronics for VR/AR applications are emphasized. Next, the detailed functionalities of skin electronic devices, including the input, output, energy devices, and integrated systems, are reviewed for future VR/AR applications.
This review introduces the materials and structures of the current advances in skin electronic devices as one of the most promising solutions for future virtual reality/augmented reality devices, including the input, output, energy devices, and integrated systems.
Robust polymeric nanofilms can be used to construct gas-permeable soft electronics that can directly adhere to soft biological tissue for continuous, long-term biosignal monitoring. However, it is ...challenging to fabricate gas-permeable dry electrodes that can self-adhere to the human skin and retain their functionality for long-term (>1 d) health monitoring. We have succeeded in developing an extraordinarily robust, self-adhesive, gas-permeable nanofilm with a thickness of only 95 nm. It exhibits an extremely high skin adhesion energy per unit area of 159 μJ/cm
The nanofilm can self-adhere to the human skin by van der Waals forces alone, for 1 wk, without any adhesive materials or tapes. The nanofilm is ultradurable, and it can support liquids that are 79,000 times heavier than its own weight with a tensile stress of 7.82 MPa. The advantageous features of its thinness, self-adhesiveness, and robustness enable a gas-permeable dry electrode comprising of a nanofilm and an Au layer, resulting in a continuous monitoring of electrocardiogram signals with a high signal-to-noise ratio (34 dB) for 1 wk.
Based on Maslow’s hierarchy of needs theory, we have proposed a novel machine learning algorithm that combines factors of the environment and its own needs to make decisions for different states of ...an agent. This means it can be applied to the gait generation of a quadruped robot, which needs to make demand decisions. To evaluate the design, we created an experimental task in order to compare the needs learning algorithm with a reinforcement learning algorithm, which was also derived from psychological motivation theory. It was found that the needs learning algorithm outperformed the reinforcement learning in tasks that involved making decisions between different levels of needs. Finally, we applied the needs learning algorithm to the problem of stable gait generation of quadruped robot, and it had achieved good results in simulation and real robot.
China is currently trying to revolutionize the primary energy industry by introducing clean energy technologies. The Chinese government has set up goals for improving energy utilization efficiency ...and environmental quality, hence finally achieving carbon neutrality. However, the conflict of interests between different parties, namely, the Chinese government, the energy industry and the third-party clean energy regulatory audit authorities, may impede the promotion of clean energy technologies. We apply the evolutionary game model involving these three parties to a theoretical analysis of the evolutionarily stable strategies adopted by these three parties. The influence factors of strategy selection for each group of stakeholders and the final form of evolutionary stable strategies adopted by each are discussed. We perform a numerical simulation of the progressive stability of several evolutionary stable strategies and the influence of parameter changes on these strategies. The results show that when the government’s initial strategy value increases from 0.2 to 0.8, the time required for game equilibrium is reduced by about 50%, which indicates that the government’s supervisory efforts adapt to the development status quo of China’s energy industry is the decisive factor for the implementation effectiveness of government policies. The government’s strong supervision over the use of clean energy technologies may adversely affect the national economic development and energy stability to a certain degree. Nevertheless, such supervision can effectively inhibit the rent-seeking behaviors between energy industry and the third-party clean energy regulatory audit authorities. Besides, strengthening the penalty while introducing appropriate incentive measures enhances the resistance of the third-party clean energy regulatory audit authorities to rent-seeking behaviors. It is necessary for China to dynamically adjust the policies for promoting clean energy technologies based on the influence factors of policy efficiency to coordinate the interests among the stakeholders and achieve a dynamic balance between the three parties.
The boomerang attack is a cryptanalysis technique that allows an attacker to concatenate two short differential characteristics. Several research results (ladder switch, S-box switch, sandwich ...attack, Boomerang Connectivity Table (BCT), ...) showed that the dependency between these two characteristics at the switching round can have a significant impact on the complexity of the attack, or even potentially invalidate it. In this paper, we revisit the issue of boomerang switching effect, and exploit it in the case where multiple rounds are involved. To support our analysis, we propose a tool called Boomerang Difference Table (BDT), which can be seen as an improvement of the BCT and allows a systematic evaluation of the boomerang switch through multiple rounds. In order to illustrate the power of this technique, we propose a new related-key attack on 10-round AES-256 which requires only 2 simple related-keys and 275 computations. This is a much more realistic scenario than the state-of-the-art 10-round AES-256 attacks, where subkey oracles, or several related-keys and high computational power is needed. Furthermore, we also provide improved attacks against full AES-192 and reduced-round Deoxys.
A LiNi0.8Co0.15Al0.05O2 (NCA) solid battery was assembled by coupling an NCA cathode with a polyvinylidene fluoride (PVDF)/Li6.75La3Z1.75Ta0.25O12 (LLZTO) composite polymer electrolyte and a Li ...anode. A NiO-like phase transition is regarded as the reason for interface impedance, which leads to drastic capacity fading during cycling. A gradient cathode with excessive addition of Li6.75La3Zr1.75Ta0.25O12 was fabricated at the cathode/electrolyte interface to overcome the increased impedance. Using high-resolution transmission electron microscopy and electron energy loss spectra, the formation of a unique localized cation migration (LCM) region was confirmed on the NCA surface. The formation of an LCM region hindered further distortion and enhanced the capacity retention of the spinel lattice.
COVID-19 is a public health emergency for human beings and brings some very harmful consequences in social and economic fields. In order to model COVID-19 and develop the effective control measures, ...this paper proposes an SEIR-type epidemic model with the contacting distance between the healthy individuals and the asymptomatic or symptomatic infected individuals, and the immigration rate of the healthy individuals since the contacting distance and the immigration rate are two critical factors which determine the transmission of COVID-19. Firstly, the threshold values of the contacting distance and the immigration rate are obtained to analyze the presented model. Secondly, based on the data from January 10, 2020, to March 18, 2020, for Wuhan city, all parameters are estimated. Finally, based on the estimated parameters, the sensitivity analysis and the numerical study are conducted. The results show that the contacting distance and the immigration rate play an important role in controlling COVID-19. Meanwhile, the extinct lag decreases as the contacting distance increases and/or the immigration rate decreases. Our study could give some reasonable suggestions for the health officials and the public and provide a theoretical issue for globally controlling the COVID-19 pandemic.
To find the best short-term daily recombinant human erythropoietin (rhEPO)-based treatment protocols for blood-saving purpose in THA.
The patients were randomized to 1 of 3 interventions: Patients in ...group A received 10,000 IU (150 IU/kg) of subcutaneous rhEPO (1 ml) daily from 5 days preoperatively to 3 days postoperatively (9 doses in total); Patients in group B received 1 ml of subcutaneous normal saline daily from 5 days preoperatively to 3 days preoperatively and then 10,000 IU (150 IU/kg) of subcutaneous rhEPO daily until 3 days postoperatively (6 doses in total). Patients in group C received 1 ml of subcutaneous normal saline daily from 5 days preoperatively to one day preoperatively and then 10,000 IU (150 IU/kg) of subcutaneous rhEPO daily from the day of surgery to 3 days postoperatively (4 doses in total).
One hundred eighty patients were included. On postoperative day one, patients in the group A showed significantly higher Hb level (108.4 ± 11.4 g/L) than group C (103.9 ± 8.8 g/L). Group B (107.8 ± 8.4 g/L) also showed significantly higher Hb level than group C (103.9 ± 8.8 g/L) (p < 0.05). On postoperative day 3, no significant difference was found between group B and group C in Hb level (98.7 ± 10.5 and 94.9 ± 8.7 g/L, respectively) (p = 0.094), but the Hb level in group A (103.6 ± 11.0 g/L) was still markedly higher than in group B and the Hb level in group A was also markedly higher than in group C. In terms of blood loss, no markedly difference was found in intraoperative blood loss among group A, B and C (78.3 ± 22.4, 84.6 ± 29.1, and 80.3 ± 23.9 ml, respectively) (p = 0.381), but on postoperative day one, the mean blood loss in group C (522.4 ± 189.4 ml) was significantly more than group B (371.2 ± 124.6 ml), and group B was also significantly more than group A (284.8 ± 112.9 ml) with 95% confidence interval, and group B had significantly less blood loss than group C (p < 0.001). With respect to the total blood loss, the total blood loss in group C (881.6 ± 314.9 ml) was significantly more than group B (642.6 ± 232.9 ml), and group B was also significantly more than group A (514.5 ± 204.6 ml) with 95% confidence interval (Table 2). Only 2 patients in each group received allogeneic blood transfusion and each patient received 2 units of red blood cells, so, the transfusion requirements among the three groups were comparable.
Daily small-dose of subcutaneous rhEPO administered from 5 days before THA could significantly decrease perioperative blood loss and improve postoperative Hb levels, without increasing risks of complications, when compared with the application of rhEPO from 3 days before THA or from the day of surgery. However, surgeons should choose the regimen individually according to different patients' personal circumstances.
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Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
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► A novel MS-based isotope reagent DMPP was developed for the derivatization toward carboxyl group. ► The simple and rapid labeling reaction was carried out under mild conditions with ...high specificity. ► The LODs of analytes containing the carboxyl and excess labeling reagent were greatly reduced. ► Enhanced accuracy in peptide sequencing was achieved by the introduction of isotope-coded DMPP.
A novel isotope labeling reagent d0-/d6-2, 4-dimethoxy-6-piperazin-1-yl pyrimidine (DMPP) has been developed for derivatization toward the carboxyl group based on carbodiimide chemistry for mass spectrometry (MS) analysis. The strengths of this derivatization strategy involve fast labeling (15s), low chemical background and general access to most carboxylic analytes. This has been demonstrated using a series of compounds containing carboxylic acids, including peptides and proteins. To enhance the MS response of the derivatized analytes, the design of DMPP has been based on integration of the theoretical consideration of high gas-phase hydrogenation capacity and hydrophobicity. In addition, the high abundance product ions at m/z 225 and m/z 231 from d0-/d6-DMPP labeled carboxylic acids indicate high efficiency of the gas-phase cleavage induced by the labeling reagent. Quantitative determination of these ions can also be used in single reaction monitoring to achieve extremely high sensitivity toward the target analytes. This has subsequently been used to determine trace free fatty acids in human urine. Furthermore, the DMPP labeled peptides also provide additional sequence information in MALDI–MS/MS because of the formation of sequence-related isotope fragment ions. This DMPP-oriented labeling technique is expected to be a promising tool for the MS detection of many varieties of compounds containing carboxyl groups.
The supercapsular percutaneously-assisted total hip arthroplasty (SuperPath) was proposed to be minimally invasive and tissue sparing with possible superior postoperative outcomes to traditional ...approaches of total hip arthroplasty (THA). Here, we compared the short-term outcomes of staged THA with the SuperPath or through posterolateral approach (PLA) for bilateral osteonecrosis of the femoral head (ONFH).
Patients with bilateral late-stage ONFH were prospectively recruited from our department from March 2017 to March 2018. Staged bilateral THAs with one side SuperPath and the other side PLA were performed consecutively in the same patients with right and left hips alternating within approaches. The average time interval between the staged THAs was 3 months. Perioperative status (operation time, incision length, intraoperative blood loss, soft tissue damage, and length of hospital stay) and postoperative function (range of motion, pain, and hip function) were recorded and compared between the SuperPath and PLA approaches within 12-month postoperatively.
Four male patients (age, 51.00 ± 4.54; BMI, 21.49 ± 1.73) with bilateral alcohol-induced ONFH (Ficat III/IV) were followed up over 12 months postoperatively. Compared with the PLA, the SuperPath yielded shorter incision length (7.62 vs. 11.12 cm), longer operation time (103.25 vs. 66.50 min), more blood loss (1108.50 vs. 843.50 ml), deficient abduction angle of the acetabular cup (38.75° vs. 44.50°), and inferior early-term hip function (Harris hip score, 72.50 vs. 83.25) at 12-month postoperatively. Soft tissue damage, length of hospital stay, postoperative pain, postoperative range of motion, and 12-month patient satisfaction were comparable between both approaches.
The SuperPath may be a minimally invasive technique but the present study shows less favorable short-term outcomes than PLA for total hip arthroplasty in osteonecrosis of the femoral head. More investigations are required to provide convincing favorable evidences of the SuperPath over other traditional THA approaches.
The trial was retrospectively registered in https://www.researchregistry.com (No. Researchregistry4993) on July 04, 2019. The first participant was enrolled on March 13, 2017.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
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