Superconductor-ferromagnet interfaces in two-dimensional heterostructures present a unique opportunity to study the interplay between superconductivity and ferromagnetism. The realization of such ...nanoscale heterostructures in van der Waals (vdW) crystals remains largely unexplored due to the challenge of making atomically-sharp interfaces from their layered structures. Here, we build a vdW ferromagnetic Josephson junction (JJ) by inserting a few-layer ferromagnetic insulator Cr
Ge
Te
into two layers of superconductor NbSe
. The critical current and corresponding junction resistance exhibit a hysteretic and oscillatory behavior against in-plane magnetic fields, manifesting itself as a strong Josephson coupling state. Also, we observe a central minimum of critical current in some JJ devices as well as a nontrivial phase shift in SQUID structures, evidencing the coexistence of 0 and π phase in the junction region. Our study paves the way to exploring sensitive probes of weak magnetism and multifunctional building-blocks for phase-related superconducting circuits using vdW heterostructures.
Under the green goals of the carbon peak and carbon neutrality, understanding how to develop the economy with high quality is an important issue facing regional development. Based on the years 2000, ...2010, and 2020, this paper studies the industrial function connection path and economic network characteristics of the Hexi Corridor through an urban flow model, dominant flow analysis, modified gravity model, and social network analysis method, and puts forward an economic synergistic development model. It is of great significance to strengthen the urban connection in the Hexi Corridor and give full play to the overall competitive advantage. The results are as follows. (1) The overall function of the urban agglomeration is weak, the outward function of manufacturing is outstanding, the complementary network is highly complicated and evolving, and the environment and public service and tourism industry have apparent advantages. (2) The backbone correlation axes of the “three industries” show the characteristics of a closed triangular connection, dual-core linkage development, and multi-center multi-axis interaction. (3) The economic network has a greater agglomeration effect than diffusion effect, with prominent grouping characteristics, forming a network structure of “one man, three vices, and many nodes” and a significant spatial proximity effect. (4) Based on geographical proximity, the “one axis, four circles, multiple points, and multiple channels” synergistic development model, which breaks administrative barriers, becomes the endogenous driving force for the evolution of the economic network.
Abstract The bulk photovoltaic effect (BPVE) in non-centrosymmetric materials has attracted significant attention in recent years due to its potential to surpass the Shockley-Queisser limit. Although ...these materials are strictly constrained by symmetry, progress has been made in artificially reducing symmetry to stimulate BPVE in wider systems. However, the complexity of these techniques has hindered their practical implementation. In this study, we demonstrate a large intrinsic photocurrent response in centrosymmetric topological insulator Ag 2 Te, attributed to the surface photogalvanic effect (SPGE), which is induced by symmetry reduction of the surface. Through diverse spatially-resolved measurements on specially designed devices, we directly observe that SPGE in Ag 2 Te arises from the difference between two opposite photocurrent flows generated from the top and bottom surfaces. Acting as an efficient SPGE material, Ag 2 Te demonstrates robust performance across a wide spectral range from visible to mid-infrared, making it promising for applications in solar cells and mid-infrared detectors. More importantly, SPGE generated on low-symmetric surfaces can potentially be found in various systems, thereby inspiring a broader range of choices for photovoltaic materials.
The aim of this study was to evaluate the risk factors and characteristics of long-term postoperative left atrial (LA) thrombi after mitral valve replacement. Transthoracic echocardiography (TTE) ...file of 3117 consecutive patients with mitral valve replacement history was reviewed (between Jan 2006 and Feb 2019). 45 LA thrombi cases (1.4%) was identified and matched to 180 thrombi-free cases by random sampling. The median detection time of LA thrombi was 58 months (IQR, 17–144) after MV replacement. Distribution of LA thrombi included roof (n = 10), posterior wall (n = 9), appendage (n = 7), lateral wall (n = 6), anterior wall (n = 2), septum (n = 1) and multiple site (n = 10). All thrombi were sessile and immobile. The independent predictors for LA thrombi development by stepwise multiple regression analysis were the larger LA size (> 55 mm), the increased of mitral valve pressure gradient (MVPG > 6 mmHg), and the reduced of left ventricular ejection fraction (LVEF < 50%). Long-term thrombi incidence after mitral valve replacement is somewhat low. In individuals with mitral prosthetic valves, larger LA size, increased MVPG and reduced LVEF were three promising independent predictors of the insistence of LA thrombi. Furthermore, LA thrombi were sessile, immobile and widespread in the long-term postoperative period after mitral valve replacement. Close monitoring should be applied in these patients with thrombi risk.
Abstract
WTe2, as a type-II Weyl semimetal, has 2D Fermi arcs on the (001) surface in the bulk and 1D helical edge states in its monolayer. These features have recently attracted wide attention in ...condensed matter physics. However, in the intermediate regime between the bulk and monolayer, the edge states have not been resolved owing to its closed band gap which makes the bulk states dominant. Here, we report the signatures of the edge superconductivity by superconducting quantum interference measurements in multilayer WTe2 Josephson junctions and we directly map the localized supercurrent. In thick WTe2 ($\sim 60{\rm{\ nm}})$, the supercurrent is uniformly distributed by bulk states with symmetric Josephson effect ($| {I_c^ + ( B )} | {=} | {I_c^ - ( B )} |\ $). In thin WTe2 (10 nm), however, the supercurrent becomes confined to the edge and its width reaches up to $1.4{\rm{\ \mu m\ }}$and exhibits non-symmetric behavior $| {I_c^ + ( B )} | \ne | {I_c^ - ( B )} |$. The ability to tune the edge domination by changing thickness and the edge superconductivity establishes WTe2 as a promising topological system with exotic quantum phases and a rich physics.
We report the evidence of edge superconductivity in multilayer WTe2 Josephson junctions which remains rarely studied in type-II Weyl semimetal.
Designing single-atom nanozymes with densely exposed metal atom active sites and enhancing catalytic activity to detect pollutants remain a serious challenge. Herein, we reported a single-atom ...nanozyme with layered stacked Fe/Cu dual active sites (Fe/Cu-NC SAzyme) synthesized via hydrothermal and high-temperature pyrolysis using folic acid as a template. Compared with Fe-NC and Cu-NC SAzyme, Fe/Cu-NC SAzyme has higher peroxidase-like activity, which indicates that the doping of synthesized Fe/Cu bimetals can improve the catalytic activity and that the atomic loading of Fe and Cu in Fe/Cu-NC is 5.5 wt% and 2.27 wt%, respectively. When S2− is added to the Fe/Cu-NC catalytic system, a high-sensitivity and high-selectivity S2− colorimetric sensing platform can be established, with a wide linear range (0.09–6 µmol/L) and a low detection limit (30 nmol/L), which can be used to detect S2− in environmental water samples. What's more, the Fe/Cu-NC SAzyme can activate peroxymonosulfate (PMS) to degrade 99.9% of rhodamine B (RhB) within 10 min with a degradation kinetics of 0.5943 min−1. This work details attractive applications in Fe/Cu-NC SAzyme colorimetric sensing and dye degradation.
Fe/Cu-NC bimetallic active site SAzymes were successfully prepared with good selectivity and peroxidase activity, which can be well applied to S2− detection and organic dye degradation. Display omitted
Bladder cancer (BLCA) is a malignancy that frequently metastasizes and leads to poor patient prognosis. It is essential to understand the molecular mechanisms underlying the progression and ...metastasis of BLCA and identify potential biomarkers.
The expression of peptidase inhibitor 16 (PI16) was analysed using quantitative PCR, immunoblotting and immunohistochemistry assays. The functional roles of PI16 were evaluated using wound healing, transwell, and human umbilical vein endothelial cell tube formation assays, as well as in vivo tumour models. The effects of PI16 on nuclear factor κB (NF-κB) signalling activation were examined using luciferase reporter gene systems, immunoblotting and immunofluorescence assays. Co-immunoprecipitation was used to investigate the interaction of PI16 with annexin-A1 (ANXA1) and NEMO.
PI16 expression was downregulated in bladder cancer tissues, and lower PI16 levels correlated with disease progression and poor survival in patients with BLCA. Overexpressing PI16 inhibited BLCA cell growth, motility, invasion and angiogenesis in vitro and in vivo, while silencing PI16 had the opposite effects. Mechanistically, PI16 inhibited the activation of the NF-κB pathway by interacting with ANXA1, which inhibited K63 and M1 ubiquitination of NEMO.
These results indicate that PI16 functions as a tumour suppressor in BLCA by inhibiting tumour growth and metastasis. Additionally, PI16 may serve as a potential biomarker for metastatic BLCA.
We present full-time-domain (FTD), moving-mesh, relativistic hydrodynamic simulations of jets launched from the center of a massive progenitor star and compute the resulting synchrotron light curves ...for observers at a range of viewing angles. We follow jet evolution from ignition inside the stellar center, propagation in the stellar envelope and breakout from the stellar surface, then through the coasting and deceleration phases. The jet compresses into a thin shell, sweeps up the circumstellar medium, and eventually enters the Newtonian phase. The jets naturally develop angular and radial structure due to hydrodynamical interaction with surrounding gas. The calculated synchrotron light curves cover the observed temporal range of prompt to late afterglow phases of long gamma-ray bursts. The on-axis light curves exhibit an early emission pulse originating in shock-heated stellar material, followed by a shallow decay and a later steeper decay. The off-axis light curves rise earlier than previously expected for top-hat jet models-on a timescale of seconds to minutes after jet breakout-and decay afterward. Sometimes the off-axis light curves have later rebrightening components that can be contemporaneous with SNe Ic-bl emission. Our calculations may shed light on the structure of GRB outflows in the afterglow stage. The off-axis light curves from FTD simulations advocate new light-curve templates for the search of off-axis/orphan afterglows.
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