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•A meter-scale ultra-low frequency wide-bandgap seismic metamaterial for Lamb waves is proposed for the first time, and the bandgap can cover the 2 Hz seismic peak spectrum.•Band ...structures, vibration modes and transmission spectrum of the seismic metamaterial are calculated and analyzed.•The influences of geometrical parameters, material parameters value on the bandgap width and location are discussed.•The structure is optimized, and the effects of the different forms of matrix on the attenuation degree of the transmission spectrum is discussed.
Seismic metamaterials (SMs) have attracted the attention of many researchers in the field of damping and elastic wave isolation because of their bandgap properties, i.e., attenuating elastic waves in the range of bandgaps. However, the dimension of these SMs often reaches the 10-meter scale, which impedes practical engineering application. To break through this bottleneck and achieve a smaller scale, a meter-scale novel SM composed of steel and rubber is proposed for attenuating ultra-low frequency seismic Lamb waves. Firstly, the finite element method is used to analyze the band structure of SMs and calculate the bandgaps. To explain the mechanism of bandgap, the vibration modes of the waves at the bandgap boundary frequency are further analyzed. Subsequently, the transmission spectrum of Lamb waves incidents on the finite SMs system is analyzed to prove the authenticity of the bandgaps. Finally, parameter analyses including the geometric variables, material properties, equivalent mass density, and structural matrix forms with identical equivalent mass density are investigated numerically. The results show that Lamb waves in the range of 0–20 Hz are significantly attenuated by SMs, and the aforementioned parameters are significant factors affecting the bandgap properties and transmission properties. The proposed SM has a smaller size while maintaining some wide bandgaps at 0–20 Hz for ultra-low frequencies. It is worth noting that the 2 Hz seismic peak spectrum causing the destruction of building structures is covered effectively.
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Amidoximated PAN fiber supported FePc as a bioinspired catalyst.The coordination of amidoxime group with FePc as the axial fifth ligand.Selective H2O2 decomposition via heterolytic ...cleavage of peroxide OO bond.Dye degradation by high-valent iron-oxo species in this catalytic process.
Iron(II) phthalocyanine was immobilized onto amidoximated polyacrylonitrile fiber to construct a bioinspired catalytic system for oxidizing organic dyes by H2O2 activation. The amidoxime groups greatly helped to anchor Iron(II) phthalocyanine molecules onto the fiber through coordination interaction, which has been confirmed by Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy and UV⿿vis diffuse reflectance spectroscopy analyses. Electron spin resonance studies indicate that the catalytic process of physically anchored Iron(II) phthalocyanine performed via a hydroxyl radical pathway, while the catalyst bonded Iron(II) phthalocyanine through coordination effect could selectively catalyze the H2O2 decomposition to generate high-valent iron-oxo species. This may result from the amidoxime groups functioning as the axial fifth ligands to favor the heterolytic cleavage of the peroxide OO bond. This feature also enables the catalyst to only degrade the dyes adjacent to the catalytic active centers and enhances the efficient utilization of H2O2. In addition, this catalyst could effectively catalyze the mineralization of organic dyes and can be easily recycled without any loss of activity.
In this paper, an analysis is made for the fully developed mixed bioconvection flow in a horizontal channel filled with a nanofluid that contains both nanoparticles and gyrotactic microorganisms. The ...passively controlled nanofluid model proposed by Kuznetsov and Nield (2013) is then introduced for modeling this flow problem, which is found to be more physically realistic than previous nanofluid models. Analytical approximations with high precision are obtained by the improved homotopy analysis technique for complicated boundary conditions. Besides, the influences of various physical parameters on the distributions of temperature, the nanoparticle volume fraction, as well as the density of motile microorganisms are investigated in detail.
•The passively controlled mathematical model for nanofluids is introduced, which could be physically more realistic than the previous models.•The influence of nanoparticles on the bioconvection is investigated.•An improved HAM technique for nonlinear problems with complicated boundary conditions is developed.
Ferroptosis is a form of iron-dependent regulated cell death. Evidence of its existence and the effects of its inhibitors on subarachnoid hemorrhage (SAH) is still lacking. In the present study, we ...found that liproxstatin-1 protected HT22 cells against hemin-induced injury by protecting mitochondrial functions and ameliorating lipid peroxidation. In
in vivo
experiments, we demonstrated the presence of characteristic shrunken mitochondria in ipsilateral cortical neurons after SAH. Moreover, liproxstatin-1 attenuated the neurological deficits and brain edema, reduced neuronal cell death, and restored the redox equilibrium after SAH. The inhibition of ferroptosis by liproxstatin-1 was associated with the preservation of glutathione peroxidase 4 and the downregulation of acyl-CoA synthetase long-chain family member 4 as well as cyclooxygenase 2. In addition, liproxstatin-1 decreased the activation of microglia and the release of IL-6, IL-1β, and TNF-α. These data enhance our understanding of cell death after SAH and shed light on future preclinical studies.
High crosslinking and low shrinkage stress are difficult to reconcile in the preparation of performance-enhancing photopolymer materials. Here we report the unique mechanism of upconversion ...particles-assisted NIR polymerization (UCAP) in reducing shrinkage stress and enhancing mechanical properties of cured materials. The excited upconversion particle emit UV-vis light with gradient intensity to the surroundings, forming a domain-limited gradient photopolymerization centered on the particle, and the photopolymer grows within this domain. The curing system remains fluid until the percolated photopolymer network is formed and starts gelation at high functional group conversion, with most of the shrinkage stresses generated by the crosslinking reaction having been released prior to gelation. Longer exposures after gelation contribute to a homogeneous solidification of cured material, and polymer materials cured by UCAP exhibit high gel point conversion, low shrinkage stress and strong mechanical properties than those cured by conventional UV polymerization techniques.
The timely and reliable handling of post-disaster emergency monitoring tasks is crucial for effective rescue operations. UAV-assisted edge computing plays a pivotal role in the rapid deployment of ...such systems. However, challenges persist due to communication and computation resource bottlenecks when dealing with delay-sensitive monitoring tasks. In dynamic post-disaster environments, effective task scheduling and resource allocation decisions directly impact the system’s ability to process tasks. Therefore, this paper proposes an adaptive task migration decision-making system for emergency monitoring tasks in UAV-assisted edge computing. Firstly, We decomposed the optimization objectives based on the task processing workflow, then devised a stepwise delay risk control and resource recovery mechanism based on early discarding. Secondly, by integrating multi-agent reinforcement learning (MARL), optimal strategies for task offloading, UAV queue scheduling, and communication resource allocation are learned to enhance the decision system’s environmental awareness and maximize the successful completion of emergency monitoring tasks. Simulation experiments demonstrate that the algorithm significantly improves the success rate of migration tasks and data processing capacity, thereby validating its convergence and effectiveness.
In this paper, a novel six-mode loop antenna covering 660-1100, 1710-3020, 3370-3900, and 5150-5850 MHz has been proposed for the application of long-term evolution (LTE) including the coming LTE in ...unlicensed spectrum and LTE-Licensed Assisted Access. Loop antennas offer better user experience than conventional planar inverted-F antennas (PIFAs), inverted-F antennas (IFAs), and monopole antennas because of their unique balanced modes (1λ, 2λ, ...). However, the bandwidth of loop antennas is usually narrower than that of PIFA/IFA and monopole antennas due to these balanced modes. To overcome this problem, a novel monopole/dipole parasitic element, which operates at an unbalanced monopole-like 0.25λ mode and a balanced dipole-like 0.5λ mode, is first proposed for loop antennas to cover more frequency bands. Benefiting from the balanced mode, the proposed parasitic element is promising to provide better user experience than conventional parasitic elements. To the best of the authors' knowledge, the balanced mode for a parasitic element is reported for the first time. The proposed antenna is able to provide excellent user experience while solving the problem of limited bandwidth in loop antennas. To validate the concept, one prototype antenna with a size of 75 × 10 × 5 mm 3 is designed, fabricated, and measured. Both simulations and experimental results are presented and discussed. Good performance is achieved.
Abstract
Cholesterol is an essential structural component of membranes that contributes to membrane integrity and fluidity. Cholesterol homeostasis plays a critical role in the maintenance of ...cellular activities. Recently, increasing evidence has indicated that cholesterol is a major determinant by modulating cell signaling events governing the hallmarks of cancer. Numerous studies have shown the functional significance of cholesterol metabolism in tumorigenesis, cancer progression and metastasis through its regulatory effects on the immune response, ferroptosis, autophagy, cell stemness, and the DNA damage response. Here, we summarize recent literature describing cholesterol metabolism in cancer cells, including the cholesterol metabolism pathways and the mutual regulatory mechanisms involved in cancer progression and cholesterol metabolism. We also discuss various drugs targeting cholesterol metabolism to suggest new strategies for cancer treatment.
As a market-based water resource management, the water rights reform (WRR) will allocate water rights to water users and allow water users to trade water rights, which can realize the reallocation ...across water users. In this context, the adoption of water-saving irrigation (WSI) is an important technical form to adapt to the reform. Based on this, this paper studies the impacts of the WRR on WSI using the difference-in-differences (DID) strategy. The results show that the WRR could increase the land area for WSI by an average of 13.63%. The WRR could promote the expansion of high-efficiency irrigation mainly because the WRR could promote the expansion of spray and drip irrigation areas, and micro-irrigation land areas, which are high-efficiency water-saving irrigation technologies. In addition, the WRR also could improve agricultural production by increasing agricultural water productivity and planting area (including the sown area of grain crops and cash crops), but the WRR does not reduce agricultural water extraction. Therefore, the WRR could increase agricultural production without increasing agricultural water extraction.
