Magnetic skyrmions, swirling nanometric spin textures, have been attracting increasing attention by virtue of their potential applications for future memory technology and their emergent ...electromagnetism. Despite a variety of theoretical proposals oriented towards skyrmion-based electronics (that is, skyrmionics), few experiments have succeeded in creating, deleting and transferring skyrmions, and the manipulation methodologies have thus far remained limited to electric, magnetic and thermal stimuli. Here, we demonstrate a new approach for skyrmion phase control based on a mechanical stress. By continuously scanning uniaxial stress at low temperatures, we can create and annihilate a skyrmion crystal in a prototypical chiral magnet MnSi. The critical stress is merely several tens of MPa, which is easily accessible using the tip of a conventional cantilever. The present results offer a new guideline even for single skyrmion control that requires neither electric nor magnetic biases and consumes extremely little energy.
Both electric- and magnetic-dipole active spin excitations, i.e., electromagnons, which mediate the dynamical magnetoelectric effect, have been investigated for a multiferroic perovskite of manganite ...by optical spectroscopy at terahertz frequencies. Upon the magnetoelectric resonance at 1 meV in the multiferroic phase with the bc-plane spin cycloidal order, a gigantic dynamical magnetoelectric effect has been observed as a nonreciprocal directional dichroism or birefringence. The light k-vector-dependent difference (Δκ=κ(+)-κ(-)) of the extinction coefficient (κ(±)) is as large as Δκ~1 or 2Δκ/(κ(+)+κ(-))~0.7 at the lowest-lying electromagnon energy. We clarified the mutual coupling of the E(ω)parallela-polarized electromagnons of the different origins, leading to the enhancement of the magnetoelectric resonance.
Elucidation of the genetic mechanisms of convergent evolution, the evolution of similar or the same phenotypes in phylogenetically independent lineages, helps predict how populations will respond to ...the same selective pressures. Convergent evolution can be caused by either the fixation of identical‐by‐descent alleles, independent mutations at the same gene, or mutations in different genes controlling the same trait. To what extent does the fixation of identical‐by‐descent alleles lead to convergent evolution in isolated populations where inflow of adaptive alleles from other populations is limited? In a From the Cover article in this issue of Molecular Ecology, Kemppainen et al. (2021) compared the genetic basis for the reduction of pelvic structures in three isolated freshwater populations of nine‐spined stickleback (Pungitius pungitius) from Northern Europe. The authors used quantitative trait loci (QTL) mapping to reveal that the pelvic reduction in these three populations was caused by mutations at different genetic loci. In contrast to studies in three‐spined stickleback (Gasterosteus aculeatus), where independently derived Pitx1 mutations were shown to be responsible for plate reduction across multiple freshwater populations, Kemppainen et al. (2021) found Pitx1 to be the candidate causative gene for only one population of P. pungitius. This study highlights the importance of genetic studies of convergent evolution, not only in the presence of gene flow but also in its absence for a better understanding of the genetic architecture of convergent evolution.
Abstract
Magnetic skyrmion is a topologically protected particle-like object in magnetic materials, appearing as a nanometric swirling spin texture. The size and shape of skyrmion particles can be ...flexibly controlled by external stimuli, which suggests unique features of their crystallization and lattice transformation process. Here, we investigated the detailed mechanism of structural transition of skyrmion lattice (SkL) in a prototype chiral cubic magnet Cu
2
OSeO
3
, by combining resonant soft X-ray scattering (RSXS) experiment and micromagnetic simulation. This compound is found to undergo a triangular-to-square lattice transformation of metastable skyrmions by sweeping magnetic field (
B
). Our simulation suggests that the symmetry change of metastable SkL is mainly triggered by the
B-
induced modification of skyrmion core diameter and associated energy cost at the skyrmion-skyrmion interface region. Such internal deformation of skyrmion particle has further been confirmed by probing the higher harmonics in the RSXS pattern. These results demonstrate that the size/shape degree of freedom of skyrmion particle is an important factor to determine their stable lattice form, revealing the exotic manner of phase transition process for topological soliton ensembles in the non-equilibrium condition.
Abstract
Power spectra of spatial fluctuations of X-ray emission may impose constraints on the origins of the emission independent of that from the energy spectra. We generated spatial power spectrum ...densities (PSDs) of blank X-ray skies observed with the Suzaku X-ray observatory utilizing the modified Δ-variance method. Using the total measured count rate as the diagnostic tool, we found that a model consisting of the sum of two components, one for the unresolved faint point sources and one for the uniform flat-field emission, can represent well the observed PSD in three different energy bands (0.2–0.5, 0.5–2, and 2–10 keV); only an upper limit is obtained for the latter component in 2–10 keV. X-ray counting rates corresponding to the best-fit PSD model functions and diffuse emission fractions were estimated, and we confirmed that the sum of the counting rates of two model components is consistent with those actually observed with the detector for all energy bands. The ratio of the flat-field counting rate to the total in 0.5–2 keV, however, is significantly larger than the diffuse emission fraction estimated from the model fits of energy spectra. We discussed that this discrepancy can be reconciled by systematic effects in the PSD and energy spectrum analyses. The present study demonstrates that the spatial power spectrum analysis is powerful in constraining the origins of the X-ray emission.
Cis-regulatory mutations often underlie phenotypic evolution. However, because identifying the locations of promoters and enhancers in non-coding regions is challenging, we have fewer examples of ...identified causative cis-regulatory mutations that underlie naturally occurring phenotypic variations than of causative amino acid-altering mutations. Because cis-regulatory elements have epigenetic marks of specific histone modifications, we can detect cis-regulatory elements by mapping and analyzing them. Here, we investigated histone modifications and chromatin accessibility with cleavage under targets and tagmentation (CUT&Tag) and assay for transposase-accessible chromatin-sequencing (ATAC-seq). Using the threespine stickleback (Gasterosteus aculeatus) as a model, we confirmed that the genes for which nearby regions showed active marks, such as H3K4me1, H3K4me3, and high chromatin accessibility, were highly expressed. In contrast, the expression levels of genes for which nearby regions showed repressive marks, such as H3K27me3, were reduced, suggesting that our chromatin analysis protocols overall worked well. Genomic regions with peaks of histone modifications showed higher nucleotide diversity within and between populations. By comparing gene expression in the gills of the marine and stream ecotypes, we identified several insertions and deletions (indels) with transposable element fragments in the candidate cis-regulatory regions. Thus, mapping and analyzing histone modifications can help identify cis-regulatory elements and accelerate the identification of causative mutations in the non-coding regions underlying naturally occurring phenotypic variations.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Ferroelectric transition has been detected in a ferrimagnetic spinel oxide of CoCr2O4 upon the transition to the conical spin order below 25 K. The direction 110 of the spontaneous polarization is ...normal to both the magnetization easy axis 001 and to the propagation axis 110 of the transverse spiral component, in accord with the prediction based on the spin-current model. The reversal of the spontaneous magnetization by a small magnetic field (approximately 0.1 T) induces the reversal of the spontaneous polarization, indicating the clamping of the ferromagnetic and ferroelectric domain walls.
Background
In veterinary medicine, congenital methemoglobinemia associated with nicotinamide adenine dinucleotide (NADH)‐cytochrome b5 reductase (b5R) deficiency is rare. It has been reported in ...several breeds of dogs, but little information is available about its etiology.
Objectives
To analyze the NADH‐cytochrome b5 reductase gene, CYB5R3, in a Pomeranian dog family with methemoglobinemia suspected to be caused by congenital b5R deficiency.
Animals
Three Pomeranian dogs from a family with methemoglobinemia were analyzed. Five healthy beagles and 5 nonrelated Pomeranian dogs without methemoglobinemia were used as controls.
Methods
Methemoglobin concentration, b5R activity, and reduced glutathione (GSH) concentration were measured, and a turbidity index was used to evaluate Heinz body formation. The CYB5R3 genes of the affected dog and healthy dogs were analyzed by direct sequencing.
Results
Methemoglobin concentrations in erythrocytes of the affected dogs were remarkably higher than those of the control dogs. The b5R activity of the affected dogs was notably lower than that of the control dogs. DNA sequencing indicated that this Pomeranian family carried a CYB5R3 gene missense variant (ATC→CTC at codon 194) that resulted in the replacement of isoleucine (Ile) by leucine (Leu).
Conclusions and Clinical Importance
This dog family had familial congenital methemoglobinemia caused by b5R deficiency, which resulted from a nonsynonymous variant in the CYB5R3 gene. This variation (c.580A>C) led to an amino acid substitution (p.Ile194Leu), and Ile194 was located in the proximal region of the NADH‐binding motif. Our data suggested that this variant in the canine CYB5R3 gene would affect function of the b5R in erythrocytes.
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