As an important platform for researchers to present their academic findings, medical journals have a close relationship between their evaluation orientation and the value orientation of their ...published research results. However, the differences between the academic impact and level of disruptive innovation of medical journals have not been examined by any study yet.
This study aims to compare the relationships and differences between the academic impact, disruptive innovation levels, and peer review results of medical journals and published research papers. We also analyzed the similarities and differences in the impact evaluations, disruptive innovations, and peer reviews for different types of medical research papers and the underlying reasons.
The general and internal medicine Science Citation Index Expanded (SCIE) journals in 2018 were chosen as the study object to explore the differences in the academic impact and level of disruptive innovation of medical journals based on the OpenCitations Index of PubMed open PMID-to-PMID citations (POCI) and H1Connect databases, respectively, and we compared them with the results of peer review.
First, the correlation coefficients of the Journal Disruption Index (JDI) with the Journal Cumulative Citation for 5 years (JCC
), Journal Impact Factor (JIF), and Journal Citation Indicator (JCI) were 0.677, 0.585, and 0.621, respectively. The correlation coefficient of the absolute disruption index (Dz) with the Cumulative Citation for 5 years (CC
) was 0.635. However, the average difference in the disruptive innovation and academic influence rankings of journals reached 20 places (about 17.5%). The average difference in the disruptive innovation and influence rankings of research papers reached about 2700 places (about 17.7%). The differences reflect the essential difference between the two evaluation systems. Second, the top 7 journals selected based on JDI, JCC
, JIF, and JCI were the same, and all of them were H-journals. Although 8 (8/15, 53%), 96 (96/150, 64%), and 880 (880/1500, 58.67%) of the top 0.1%, top 1%, and top 10% papers selected based on Dz and CC
, respectively, were the same. Third, research papers with the "changes clinical practice" tag showed only moderate innovation (4.96) and impact (241.67) levels but had high levels of peer-reviewed recognition (6.00) and attention (2.83).
The results of the study show that research evaluation based on innovative indicators is detached from the traditional impact evaluation system. The 3 evaluation systems (impact evaluation, disruptive innovation evaluation, and peer review) only have high consistency for authoritative journals and top papers. Neither a single impact indicator nor an innovative indicator can directly reflect the impact of medical research for clinical practice. How to establish an integrated, comprehensive, scientific, and reasonable journal evaluation system to improve the existing evaluation system of medical journals still needs further research.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
Conductive thermoplastic polyurethane (TPU) nanocomposites filled with graphene were fabricated and tested for organic vapor sensing. The observed finely dispersed graphene in the TPU matrix ...benefited from the formation of efficient conductive paths and the generation of stable electrical signals. Organic vapor sensing behaviors of the conductive polymer composites (CPCs) were evaluated using four kinds of organic vapors possessing different polarities (
p
), including cyclohexane (
p
= 0.1), tetrachloromethane (CCl
4
,
p
= 1.6), ethylacetate (
p
= 4.3) and acetone (
p
= 5.4). Unlike conventional CPCs that only respond to certain specific groups of organic vapors, the current CPCs showed a novel negative vapor coefficient (NVC) effect for all tested vapors. This observed NVC was due to both the inherent microphase segregation structure of TPU containing soft and hard segments and the wrinkled structure of graphene. In successive immersion-drying runs (IDRs) at 30 °C, fast response, good reversibility and reproducibility were observed for the non- and low- polar vapors (cyclohexane and CCl
4
), but residual resistance was observed for polar organic vapors (ethylacetate and acetone) after their desorption. The temperature dependent vapor sensing behaviors indicated that the vapor sensing responsivity increased with increasing the temperature due to higher absorption activation energy at higher temperature. This study provides guidelines for the fabrication of organic vapor sensors using CPCs possessing fast response, good discrimination ability and reproducibility.
Stomata are microscopic openings that allow for the exchange of gases between plants and the environment. In
, stomatal patterning is specified by the ERECTA family (ERf) receptor kinases (RKs), the ...receptor-like protein (RLP) TOO MANY MOUTHS (TMM), and EPIDERMAL PATTERNING FACTOR (EPF) peptides. Here we show that TMM and ER or ER-LIKE1 (ERL1) form constitutive complexes, which recognize EPF1 and EPF2, but the single ERfs do not. TMM interaction with ERL1 creates a binding pocket for recognition of EPF1 and EPF2, indicating that the constitutive TMM-ERf complexes function as the receptors of EPF1 and EPF2. EPFL9 competes with EPF1 and EPF2 for binding to the ERf-TMM complex. EPFL4 and EPFL6, however, are recognized by the single ERfs without the requirement of TMM. In contrast to EPF1,2, the interaction of EPFL4,6 with an ERf is greatly reduced in the presence of TMM. Taken together, our data demonstrate that TMM dictates the specificity of ERfs for the perception of different EPFs, thus functioning as a specificity switch for the regulation of the activities of ERfs.
Diesel fuel contamination of aquifers is a global environmental problem. In recent years, in situ thermal remediation (ISTR) has attracted much attention owing to its advantages of high removal rate ...and rapid remediation. In this study, the treatment of a diesel-contaminated aquifer with thermal conduction heating (TCH) was studied. And for the purpose of making full use of the TCH residual heat, its combination with in situ chemical oxidation (ISCO) was also investigated. Results show that a maximum total petroleum hydrocarbon (TPH) removal of 70.3% or 81.73% was observed for the TCH treatment of the solid or water phase, respectively, highlighting the possibility of successfully and simultaneously remediating both aquifer phases. The effect of evaporation/boiling plays a major role in final contaminant removal processes. And the water-diesel mixture started co-boiling at 100.3℃ theoretically according to Antoine equation and Raoult’s law. The higher the temperature is, the higher the initial TPH concentration and the larger the removal rate of pollutants. The dosage of persulfate (PS) required by the system became lower with the temperature increasing, and the contribution of oxidation to the pollutant removal became greater, with the proportion of oxidation increasing from 29.05 to 66.87% from 40 to 80 °C. In the 2-D remediation experiment, the area of the heated zone above 80℃ accounted for 71.0% of the whole tank. At the heating time of 180 min, the average aqueous TPH concentration in the tank was about 248.7 mg/L and a lowest concentration of 73.1 mg/L was found around the heating resistance. During the cooling process after TCH, 97.9% of the heated area of the tank was above 30 °C when the heating resistance was turned off for 6 h, which was sufficient to activate PS for removing pollutants. Hence, TCH treatment could be an optimal method for the rapid remediation of diesel-contaminated aquifers, and the combination of TCH and ISCO can not only expand the treatment zone, but also reduce the cost of remediation.
The nucleotide-binding domain- and leucine-rich repeat (LRR)-containing proteins (NLRs) function as intracellular immune receptors to detect the presence of pathogen- or host-derived signals. The ...mechanisms of how NLRs sense their ligands remain elusive. Here we report the structure of a bacterial flagellin derivative in complex with the NLR proteins NAIP5 and NLRC4 determined by cryo-electron microscopy at 4.28 Å resolution. The structure revealed that the flagellin derivative forms two parallel helices interacting with multiple domains including BIR1 and LRR of NAIP5. Binding to NAIP5 results in a nearly complete burial of the flagellin derivative, thus stabilizing the active conformation of NAIP5. The extreme C-terminal side of the flagellin is anchored to a sterically constrained binding pocket of NAIP5, which likely acts as a structural determinant for discrimination of different bacterial flagellins by NAIP5, a notion further supported by biochemical data. Taken together, our results shed light on the molecular mechanisms underlying NLR ligand perception.
The COVID-19 outbreak brought online learning to the forefront of education. Scholars have conducted many studies on online learning during the pandemic, but only a few have performed quantitative ...comparative analyses of students’ online learning behavior before and after the outbreak. We collected review data from China’s massive open online course platform called icourse.163 and performed social network analysis on 15 courses to explore courses’ interaction characteristics before, during, and after the COVID-19 pan-demic. Specifically, we focused on the following aspects: (1) variations in the scale of online learning amid COVID-19; (2a) the characteristics of online learning interaction during the pandemic; (2b) the characteristics of online learning interaction after the pandemic; and (3) differences in the interaction characteristics of social science courses and natural science courses. Results revealed that only a small number of courses witnessed an uptick in online interaction, suggesting that the pandemic’s role in promoting the scale of courses was not significant. During the pandemic, online learning interaction became more frequent among course network members whose interaction scale increased. After the pandemic, although the scale of interaction declined, online learning interaction became more effective. The scale and level of interaction in Electrodynamics (a natural science course) and Economics (a social science course) both rose during the pan-demic. However, long after the pandemic, the Economics course sustained online interaction whereas interaction in the Electrodynamics course steadily declined. This discrepancy could be due to the unique characteristics of natural science courses and social science courses.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
With the development of the digital age, “digital learning and innovation” is becoming more and more important in the core literacy of information technology discipline. Through the elaboration of ...relevant concepts, this paper explores the connotation and concrete performance of “digital learning and innovation” literacy of senior high school students, and then obtains its three manifestations: the collection and management of digital learning resources, the adaptation of digital environment, the application and innovation of digital learning resources. On this basis, a questionnaire survey was designed to understand the status of “digital learning and innovation” literacy of high school students in S Middle School of Anhui Province, and the data results were analysed. It was found that senior high school students generally have this literacy, but some students still have some problems and need teachers’ timely guidance. Therefore, this study further proposes strategies for achieving high school students’ “digital learning and innovation” literacy to assist teachers in reminding students of “digital learning and innovation literacy” in teaching.
The practical application of energetic materials, particularly 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (CL-20), is frequently impeded by phase transition challenges. In this study, ...we propose a novel strategy to enhance the stability of CL-20 by employing a thermo-sensitive polymer, poly(N-isopropylacrylamide) (PNIPAM), to modulate its phase transitions. Our approach involves the use of an in-situ polymerized polydopamine (PDA) shell as a platform for surface grafting through atom transfer radical polymerization, yielding a core-shell structured CL-20@PDA-PNIPAM. Through comprehensive characterization, the successful grafting of PNIPAM is confirmed, significantly enhanced the phase stability of CL-20. Notably, our core-shell structure exhibits a 13 °C increase in phase transition temperature compared to raw CL-20, thereby delaying the ε→α phase transition by over 80 min under combined thermal and solvent conditions. The enhanced stability is attributed to the hydrophobic nature of PNIPAM above its low critical solution temperature in water, which effectively shields the CL-20 crystal. These findings provide new insights into enhancing the stability and safety of energetic materials in complex environments, highlighting the potential of our molecular switch mechanism.
Apply a gentle, environmentally friendly surface functionalization technique to create molecular osmotic switches on the surface of energetic crystals. Display omitted
•Atom transfer radical polymerization for surface grafting to form a compact core-shell structure.•Create molecular osmotic switches that selectively isolate solvent molecules to induce energetic crystals.•Enhance the thermal stability of energetic crystals while improving their stability in solvents.
Science, Technology, Engineering, and Math (STEM) education emphasizes solving problems in authentic contexts and developing 21st-century skills. It also helps to cultivate individuals possessing ...scientific curiosity and innovative abilities. These capacities align with China’s core literacy training. Recent years have seen K–12 STEM cases flourish nationally. However, little attention has been paid to the shared characteristics of these practices, and suggestions for implementing STEM in primary and secondary schools are scarce. This paper presents commonalities in STEM practices within China from a curriculum perspective and offers recommendations for implementation based on these attributes. Specifically, this study first constructed analytical metrics
via
the Delphi method to assess STEM cases. Next, 51 typical STEM teaching cases in different regions of China were analyzed using these metrics. Based upon the statistical results, five characteristics of STEM cases were summarized: China’s STEM education has an unbalanced geographical distribution; current practices benchmark the need for innovative talent training; most instructional content is drawn from real-world problems, but interdisciplinary integration deserves closer focus; the cases featured rich teaching activities and were conducted in a project-based learning fashion with insufficient emphasis on mathematical applications; and China seems to be holistically promoting STEM education, especially through new technologies and supplementary materials. Findings should allow instructors to better understand the intricacies of STEM implementation and to promote successful STEM cases. Recommendations are also provided to optimize the localization of STEM education in China in order to cultivate innovative and interdisciplinary talent.
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