High coupled split reactor (HCSR) makes it possible for paralleled circuit breakers to interrupt current which exceeds short circuit current interrupting capacity of a single circuit breaker. ...However, the result of simulation shows that HCSR has effect on transient recovery voltage (TRV) in the interrupting process. To analyze the impact on recovery voltage, this paper analyzes the relationship between rate of rise of recovery voltage (RRRV) of paralleled circuit breakers and parameters of HCSR as well as the stray capacitance, determines the impact of HCSR on TRV in the synchronous or non-synchronous interrupting process on the basis of theoretical analysis and deduction in the equivalent circuit. The research results above can be used as the principle of selecting circuit breakers and determining parameters of HCSR and the reference for the design of the paralleled circuit breakers.
Yuan Yu,1 Huihong Li,2 Ying Sun1 1Department of Education, School of Education, Tianjin University, Tianjin, People's Republic of China; 2Administration Department, Tianjin Experimental Kindergarten, ...Tianjin, People's Republic of ChinaCorrespondence: Ying SunDepartment of Education, School of Education, Tianjin University, Tianjin, People's Republic of ChinaTel +86 22 2740 5948Email sunyingtju@126.com We read with great interest the article by Styk et al.1 In their study, the authors found that persistence is associated with body image which evaluated by subjective body weight assessment. In addition, a positive correlation between the distractor resistance index and body mass index (BMI) was found. We wish to express our opinion on the topic and statistical method in this research. View the original paper by Wojciech Styk and colleagues
Background and purposeAn analysis of the ASTER 2 trial revealed similar final recanalisation levels and clinical outcomes in acute large vessel occlusion (LVO) stroke between stent retrieval (SR) ...alone as a first-line mechanical thrombectomy (MT) technique (SR alone first-line) and concomitant use of contact aspiration (CA) plus SR as a first-line MT technique (SR+CA first-line). The purpose of the present study was to compare the safety and efficacy of SR+CA first-line with those of SR alone first-line for patients with LVO in China.MethodsWe conducted the present study by using the data from the ANGEL-ACT registry. We divided the selected patients into SR+CA first-line and SR alone first-line groups. We performed logistic regression and generalised linear models with adjustments to compare the angiographic and clinical outcomes, including successful/complete recanalisation after the first technique alone and all procedures, first-pass successful/complete recanalisation, number of passes, 90-day modified Rankin Scale, procedure duration, rescue treatment and intracranial haemorrhage within 24 hours.ResultsOf the 1233 enrolled patients, 1069 (86.7%) received SR alone first-line, and 164 (13.3%) received SR+CA first-line. SR+CA first-line was associated with more thrombectomy passes (3 (2–4) vs 2 (1–2); β=1.77, 95% CI=1.55 to 1.99, p<0.001), and longer procedure duration (86 (60–129) min vs 80 (50–122) min; β=10.76, 95% CI=1.08 to 20.43, p=0.029) than SR alone first-line group. Other outcomes were comparable (all p>0.05) between the two groups.ConclusionsPatients undergoing SR+CA first-line had more thrombectomy passes and longer procedure duration than patients undergoing SR alone first-line. Additionally, we suggested that SR+CA first-line was not superior to SR alone first-line in final recanalisation level, first-pass recanalisation level and 90-day clinical outcomes in the Chinese population.
Croton tiglium (
Croton tiglium L., Euphorbiaceae) is widely used as a herb for treatment of gastrointestinal disturbances. Previous studies established its purgative and inflammational properties. ...The present study aimed to investigate the effects of
Croton tiglium oil (CO) on intestinal transit in mice.
Gastrointestinal transit in mice and contractile characteristics of isolated intestinal strips from mice were evaluated. Intestinal inflammation was confirmed by histological examination.
Low dose of CO increased the gastrointestinal transit of charcoal and barium meal as well as the production of fecal pellets in mice. In contrast, high dose exerted inhibitory effects. For normal colonic circular strips, both high and low dose of CO inhibited the contractile frequency. Low doses (0–20
μg/ml) of CO enhanced the phasic contractions, while high doses (>40
μg/ml) reduced them. Colonic longitudinal strips in CO-treated mice were less sensitive to electrical field stimulation than those in control mice. The contraction of colonic longitudinal, colonic and jejunal circular strips in CO-treated mice was more sensitive to atropine than that in control mice.
CO might modulate gastrointestinal motility and induce intestinal inflammation related to immunological milieu and motor activity. Our findings may highlight the ethno-medical uses of
Croton tiglium on intestinal disorders.
AI accelerators provide a promising influence for the deployment of deep learning model on edge devices, and an effective compiler can reduce great workload when deploying the models. Multi-level ...intermediate representations (MLIR) framework offers a general and efficient solution for compiling and deploying deep learning models on AI hardware because of its reusable and extensible compiler infrastructure. This work utilizes the MLIR framework to compile PaddlePaddle models, and then uses the back-end compiler to generate the target machine codes (bmodel) which are then deployed on an AI hardware--BM1684X. The experimental results show that the compilation of the YOLOv5s model from the PaddlePaddle framework into the MLIR file taking 4.636 seconds without any loss of accuracy, whose time cost is 20% less than compiling the YOLOv5s model from ONNX. The bmodel file, using the FP16 strategy, is executed on the BM1684X processor within 6.508 milliseconds, from loading the model's inputs to outputs. Moreover, employing model in local non-quantization strategy can reduce the entire computing time by 40% with a loss of 1 % accuracy.
BackgroundLipid storage myopathy (LSM) is an autosomal recessive inherited lipid and amino metabolic disorder with great clinical heterogeneity. Variations in the electron transfer flavoprotein ...dehydrogenase (ETFDH) gene cause multiple acyl-CoA dehydrogenase deficiency (MADD), and have a manifestation of LSM. Muscle biopsy helps clarify the diagnosis of LSM, and next-generation sequencing (NGS) can be useful in identifying genomic mutation sites. The diagnosis of MADD contributes to targeted therapy. Case presentationWe report on a teenager who appeared to have muscle weakness and exercise intolerance at the onset. Before the referral to our hospital, he was unsuccessfully treated with glucocorticoid for suspected polymyositis. The next-generation sequencing of the proband and his parents revealed heterozygous variations, c.365G>A (p.G122D) inherited from the father, c.176-194_176-193del, and c.832-316C>T inherited from the mother in the ETFDH gene. The tandem mass spectrometry identified the mutations to be pathogenic. However, his parents and his younger sister who were detected with a mutation of c.365G>A presented no clinical symptoms. This indicates that the combination of the three compound heterozygous mutations in ETFDH is significant. After MADD was diagnosed, a dramatic clinical recovery and biochemical improvement presented as riboflavin was given to the patient across a week, which further confirmed the diagnosis of MADD. ConclusionOur observations extend the spectrum of ETFDH variants in Chinese the population and reinforce the role of NGS in diagnosis of MADD. Early diagnosis and appropriate treatment of LSM lead to great clinical efficacy and avoid some lethal complications.
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