Two forms of Mayer–Rokitansky–Kuster–Hauser (MRKH) syndrome are recognized: isolated uterovaginal agenesis and associated with extragenital malformations, including several well-recognized syndromes. ...Trichorhinophalangeal syndrome (TRPS) is a rare autosomal dominant condition characterized by facial dysmorphism, ectodermal and skeletal features. TRPS comprises TRPSI (caused by a heterozygous pathogenic variant in TRPS1), TRPSII (caused by contiguous gene deletion of TRPS1, RAD21, and EXT1). Genital anomalies occur particularly in TRPSII. We present a case of rare combination TRPSII with MRKH syndrome. Delayed diagnosis resulted to prolonged pain syndrome and repeated surgery. Recognition of genital anomalies in TRPS allows timely referral diagnosis and appropriate care by paediatrician and adolescent gynaecologists.
The present article highlights the development of the theoretical and methodological approaches to definition of subject domain of regional economy and ensuring stability of regional development. The ...main subject of this research is the grain production complex as reproduction system, taking into account its role in ensuring food security of the country and its regions. Results of research offer the effective proof to that the grain independence represents the function from the existing solvent demand of the population for food. In the absolute parameters, it is sufficient for full providing which allows the effectively usage of stimulation factors of grain farm development within policy of national security. It also becomes a major factor of providing food and economic security of the state and its regions in modern conditions. Keywords: regional development, reproduction, grain independence, sustainable development JEL Classifications: P25; Q01
The present article highlights the development of the theoretical and methodological approaches to definition of subject domain of regional economy and ensuring stability of regional development. The ...main subject of this research is the grain production complex as reproduction system, taking into account its role in ensuring food security of the country and its regions. Results of research offer the effective proof to that the grain independence represents the function from the existing solvent demand of the population for food. In the absolute parameters, it is sufficient for full providing which allows the effectively usage of stimulation factors of grain farm development within policy of national security. It also becomes a major factor of providing food and economic security of the state and its regions in modern conditions. Keywords: regional development, reproduction, grain independence, sustainable development JEL Classifications: P25; Q01
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