KM3NeT is a network of submarine Cherenkov neutrino telescopes under construction at two different sites in the Mediterranean Sea. ARCA, near Sicily in Italy, is optimised for the detection of cosmic ...neutrinos while ORCA, near Toulon in France, is optimized for atmospheric neutrinos. ARCA and ORCA are both arrays of thousands of optical sensors (Digital Optical Modules - DOMs), each consisting of 31 small photomultipliers (PMTs) housed inside a glass sphere, which detect the Cherenkov light produced by the secondary particles generated in the neutrino interactions. 18 DOMs are arranged on flexible strings, referred to as vertical Detection Units (DUs), anchored to the sea floor. Once completed, ARCA and ORCA will consist of 230 and 115 DUs, respectively. Each DOM of a string communicates at a dedicated wavelength to the shore station via a network of optical fibers transmitting optical and acoustic signal information as well as orientation information. Before the deployment, each DU is tested and calibrated in a dark room. The test bench is equipped with a full data acquisition system for communication, data processing, and time synchronisation. Several steps are needed to accomplish the DU calibration, including the High-Voltage (HV) tuning of the PMTs, checking of the acoustic receivers and calibration light sources in the DOM, and time calibration using laser signals distributed to all DOMs. Here, we describe the DU test and calibration facility at the CAPACITY laboratory (Campania AstroPArtiCle InfrastrucTure facilitY) in Caserta, focusing on the functional tests and calibrations performed at the end of the DU integration.
Gamma-Ray Bursts (GRBs) are considered very interesting astrophysical sources to be studied in the context of neutrino astronomy. Indeed, their jet composition continues to be an open issue. Within ...the framework of the fireball model, mesons can be produced during photo-hadronic interactions occurring in the internal shocks between shells emitted by the central engine. From their decays, high-energy gamma rays and neutrinos are expected to be generated. Neutrino telescopes are particularly interested in GRBs: being the most powerful explosions observable in the Universe, they are potentially able to achieve the energetics required to contribute to the diffuse astrophysical neutrino flux measured few years ago by IceCube. The analysis here presented relies on the search of time and space coincidences between neutrinos and the GRB emission. The undersea neutrino telescope ANTARES, operational in the Northern hemisphere since 2008 in its full configuration, plays an important role in the cosmic neutrino searches. In this contribution, the results of a stacked search for astrophysical muon neutrinos are presented for 784 GRBs in the period 2007-2017 using the ANTARES data. Given the absence of coincidences between a neutrino and a GRB in the considered sample, this analysis has allowed to constrain the contribution of the detected GRB population to the neutrino diffuse flux to be less than 10% around 100 TeV, within the context of the internal shock model. In addition, for the first time in this kind of analysis, the uncertainties on the not well characterised GRB parameters, needed to compute the neutrino flux expectations, are taken into account for each individual burst and then propagated to the diffuse flux from GRBs and to the estimated stacked upper limit.
The endogenous opioid system has been implicated in alcohol consumption and preference in both humans and animals. The mu opioid receptor (MOR) is expressed on multiple cells in the striatum, however ...little is known about the contributions of specific MOR populations to alcohol drinking behaviors. The current study used mice with a genetic deletion of MOR in cholinergic cells (ChAT-Cre/Oprm1fl/fl) to examine the role of MORs expressed in cholinergic interneurons (CINs) in home cage self-administration paradigms. Male and female ChAT-Cre/Oprm1fl/fl mice were generated and heterozygous Cre+ (knockout) and Cre- (control) mice were tested for alcohol consumption in two drinking paradigms: limited access “Drinking in the Dark” and intermittent access. Quinine was added to the drinking bottles in the DID experiment to test aversion-resistant, “compulsive” drinking. Nicotine and sucrose drinking were also assessed so comparisons could be made with other rewarding substances. Cholinergic MOR deletion did not influence consumption or preference for ethanol (EtOH) in either drinking task. Differences were observed in aversion-resistance in males with Cre + mice tolerating lower concentrations of quinine than Cre-. In contrast to EtOH, preference for nicotine was reduced following cholinergic MOR deletion while sucrose consumption and preference was increased in Cre+ (vs. Cre-) females. Locomotor activity was also greater in females following the deletion. These results suggest that cholinergic MORs participate in preference for rewarding substances. Further, while they are not required for consumption of alcohol alone, cholinergic MORs may influence the tendency to drink despite negative consequences.
•It is not known how specific MOR populations contribute to alcohol drinking.•ChAT-Cre/Oprm1fl/fl mice have MOR deletion on cholinergic neurons.•Cholinergic MOR deletion increased quinine-resistant EtOH consumption in male mice.•Cholinergic MOR deletion decreased preference for nicotine, but not alcohol.•Cholinergic MOR deletion increased sucrose consumption and locomotion in females.
The ANTARES detector is an undersea neutrino telescope in the Mediterranean Sea. The search for pointlike neutrino sources is one of the main goals of the ANTARES telescope, requiring a reliable ...method to evaluate the detector angular resolution and pointing accuracy. This work describes the study of the Sun "shadow" effect with the ANTARES detector. The shadow is the deficit in the atmospheric muon flux in the direction of the Sun caused by the absorption of the primary cosmic rays. This analysis is based on the data collected between 2008 and 2017 by the ANTARES telescope. The observed statistical significance of the Sun shadow detection is 3.7σ, with an estimated angular resolution of 0.59° ± 0.10° for downward-going muons. The pointing accuracy is found to be consistent with the expectations and no evidence of systematic pointing shifts is observed.
This work presents a new search for magnetic monopoles using data taken with the ANTARES neutrino telescope over a period of 10 years (January 2008 to December 2017). Compared to previous ANTARES ...searches, this analysis uses a run-by-run simulation strategy, with a larger exposure as well as a new simulation of magnetic monopoles taking into account the Kasama, Yang and Goldhaber model for their interaction cross-section with matter. No signal compatible with the passage of relativistic magnetic monopoles is observed, and upper limits on the flux of magnetic monopoles with β=v/c≥0.55, are presented. For ultra-relativistic magnetic monopoles the flux limit is ∼7×10−18 cm−2s−1sr−1.
Over the last decade, choked jets have attracted particular attention as potential sources of high-energy cosmic neutrinos. Testing this hypothesis is challenging because of the missing gamma-ray ...counterpart, hence the identification of other electromagnetic signatures is crucial. A choked-jet source is expected harboring in core-collapse supernovae with extended hydrogen envelopes, leading to the release of ultraviolet and optical emission for a few days. The ultraviolet band will be visible with an unprecedentedly large field of view by the future mission satellite ULTRASAT, for which we investigate the detection prospects in relation to the chocked source visibility in the optical band with the currently operating telescope ZTF. As these sources can produce neutrinos via hadronic and photohadronic interactions in choked jets, we also investigate how neutrino observations by existing Cherenkov high-energy neutrino telescopes (as IceCube and KM3NeT) can be used in association with electromagnetic signals coming from shock breakout events. By considering fiducial parameters of the source population and instruments performances, we estimate the maximum redshift up to which ULTRASAT and ZTF are able to detect ultraviolet and optical signals from these explosions, respectively. Furthermore, we discuss coordinated multi-messenger observations among those instruments and high-energy neutrino telescopes. ULTRASAT will be able to double the volume of sky currently visible by ZTF for the same emitting sources enlarging the sample of observed Type II supernovae by around 60%. For optimized multi-messenger detections, the delay between neutrino produced at the shock breakout occurrence (during the jet propagation inside the stellar envelope) and ULTRASAT observations should be of around 4(5) days, with a subsequent follow-up by instruments like ZTF about one week after.
The recently discovered TeV emission from Gamma-Ray Bursts (GRBs) hints towards a possible hadronic origin of this radiation component. We developed a Monte Carlo (MC) simulation reproducing the ...kinematics of photo-hadronic interactions at internal shocks, including the pair production process that the secondary gamma rays undergo in the GRB jet. We find that sub-TeV observations of GRB 190114C can be reproduced by a baryonic energy content comparable to that in sub-GeV photons and a bulk Lorentz factor \(\Gamma=100\), with a ms variability timescale. Neutrino flux predictions by the model are found to be consistent with experimental upper limits set by ANTARES and IceCube.
Neutrinos with energies ranging from GeV to sub-TeV are expected to be produced in Gamma-Ray Bursts (GRBs) as a result of the dissipation of the jet kinetic energy through nuclear collisions ...occurring around or below the photosphere, where the jet is still optically thick to high-energy radiation. So far, the neutrino emission from the inelastic collisional model in GRBs has been poorly investigated from the experimental point of view. In the present work, we discuss prospects for identifying neutrinos produced in such collisionally heated GRBs with the large volume neutrino telescopes KM3NeT and IceCube, including their low-energy extensions, KM3NeT/ORCA and DeepCore, respectively. To this aim, we evaluate the detection sensitivity for neutrinos from both individual and stacked GRBs, exploring bulk Lorentz factor values ranging from 100 to 600. As a result of our analysis, individual searches appear feasible only for extreme sources, characterized by gamma-ray fluence values at the level of F\(_{\gamma} \geq 10^{-2}\) erg cm\(^{-2}\). In turn, it is possible to detect a significant flux of neutrinos from a stacking sample of ~ 900 long GRBs (that could be detected by current gamma-ray satellites in about five years) already with DeepCore and KM3NeT/ORCA. The detection sensitivity increases with the inclusion of data from the high-energy telescopes, IceCube and KM3NeT/ARCA, respectively.