The purpose of this study was to evaluate the efficacy and safety of erythropoietin in neonatal hypoxic-ischemic encephalopathy (HIE), by using a randomized, prospective study design.
A total of 167 ...term infants with moderate/severe HIE were assigned randomly to receive either erythropoietin (N = 83) or conventional treatment (N = 84). Recombinant human erythropoietin, at either 300 U/kg (N = 52) or 500 U/kg (N = 31), was administered every other day for 2 weeks, starting <48 hours after birth. The primary outcome was death or disability. Neurodevelopmental outcomes were assessed at 18 months of age.
Complete outcome data were available for 153 infants. Nine patients dropped out during treatment, and 5 patients were lost to follow-up monitoring. Death or moderate/severe disability occurred for 35 (43.8%) of 80 infants in the control group and 18 (24.6%) of 73 infants in the erythropoietin group (P = .017) at 18 months. The primary outcomes were not different between the 2 erythropoietin doses. Subgroup analyses indicated that erythropoietin improved long-term outcomes only for infants with moderate HIE (P = .001) and not those with severe HIE (P = .227). No negative hematopoietic side effects were observed.
Repeated, low-dose, recombinant human erythropoietin treatment reduced the risk of disability for infants with moderate HIE, without apparent side effects.
By combining the asymptotic correction scheme of Casida and Salahub for exchange-correlation potentials and the phenomenological linear correlation between experimental ionization potentials and ...highest occupied Kohn−Sham (KS) orbital energies found by Zhan, Nichols, and Dixon, we propose a new, expedient, and self-contained asymptotic correction to exchange-correlation potentials in KS density functional theory (DFT) for use in time-dependent density functional theory (TDDFT) that does not require an ionization potential as an external parameter from a separate calculation. The asymptotically corrected (TD)DFT method is implemented in the quantum chemistry program suite NWChem for both sequential and massively parallel execution. The asymptotic correction scheme combined with the B3LYP functional B3LYP(AC) is shown to be well balanced for both valence- and Rydberg-type transitions, with average errors in excitation energies of CO, N2, CH2O, and C2H4 being smaller than those of uncorrected BLYP and B3LYP TDDFT by factors of 4 and 2, respectively, consistent with the improved orbital energies found for B3LYP(AC). We demonstrate the general applicability and accuracy of the method for the Rydberg excited states of mono- to tetrafluorinated methanes, the valence and Rydberg excited states of benzene, and the Q, B, N, and L band positions of free-base porphin.
We have been researching Solid oxide fuel cells (SOFCs) with Cu-CeO
2-ScSZ (scandia stabilized zirconia) anodes operating directly on ethanol fuels in recent years. In this paper, Cu-CeO
2-ScSZ ...anodes with different Cu/CeO
2 composition are fabricated by dry pressing, sintering and wet impregnation technologies. The photographs and SEM images of these samples after exposure to ethanol fuels for 300 h are observed to characterize their carbon deposition behaviors. The different deposited carbon morphologies in the anodes with different compositions are recorded, and possible reaction mechanisms and prevention methods are discussed. Based on these results; we demonstrate the carbon deposition behaviors and degradation reasons for the single cell running in ethanol fuels.
► The deposited carbon morphologies in Cu-CeO
2-ScSZ anodes were recorded. ► Several strategies were provided to prevent carbon deposition. ► These results help to justify whether there are carbon depositions in the anodes. ► Co and Ni were added to improve anode performances.
Summary
The effects of fermentation of whole polished rice grains on the physical properties of rice flour and the rheological characteristics of rice noodles were investigated. Natural fermentation ...had little effect on the crystalline structure of rice starch, as measured by X‐ray diffraction, but the ratio of the crystalline to the amorphous regions increased. The thermal properties of rice flours were determined using differential scanning calorimetry and a rapid viscosity analyser (RVA). The gelatinization temperature, Tp, and the RVA peak viscosity of rice flour decreased, while the gelatinization enthalpy, ΔH, increased after fermentation. The FTIR spectra of fermented and control rice flours were similar. Fermented rice starch granules had slight superficial corrosion when examined using scanning electron microscopy. Fermentation may thus change the amorphous region of the starch granule as well as the chemical components and thereby modify both physical properties of rice flour and rheological characteristics of rice noodles.
Storage rings, dedicated small accelerators and experimental setups have been established during past few years in Lanzhou China. The commissioning of the heavy ion Cooler Storage Rings gained great ...success. These advances give good opportunities for atomic physics researches using highly charged ions. The current status of the accelerators, some experimental setups will be introduced. Examples of some research results will be selected and reported. The future aspects of atomic physics related to ion-matter interactions will be outlined.
The northwestern region of China is mainly semi-arid to arid and loess is ubiquitous. This natural resource has considerable potential to be transformed into earthen final covers for local landfills, ...but first its suitability must be ascertained through extensive tests. In this study, a device was developed to measure the gas permeability of unsaturated compacted loess specimens. Experiments were carried out to investigate the influence of clod size, compaction water content, and post-compaction water content on the gas permeability of the compacted loess. To maintain an identical soil structure, the post-compaction water content was changed using the osmotic technique. It was found that the compaction water content and resultant soil clod size exerted a combined effect on the gas permeability such that, at low water contents, the gas permeability remained fairly constant, but at high water contents the clods became relatively large, and the effect of the clod size dominated the water blockage effect from increasing water content. For specimens with identical soil structure, the gas permeability decreased with the increasing post-compaction degree of saturation at an accelerated rate. A power function is proposed to predict the relationship between the gas permeability normalized by the porosity function of the Kozeny-Carmen model and the post-compaction degree of saturation. Analysis of the experimental data indicates that the parameters for the power function still depend on the porosity of the compacted loess, particularly at high degrees of saturation.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
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