Despite much recent effort, the highest reported T c of the infinite-layer nickelates remains lower than 15 K. Here, the authors apply pressure to Pr0.82Sr0.18NiO2 thin films and observe a monotonic ...increase of T c to 31 K at 12.1 GPa, an increase that does not level off with increasing pressure.
The formation of polar cap density enhancements, such as tongues‐of‐ionization (TOIs), are often attributed to enhanced dayside reconnection and convection due to solar wind changes. However, ...ionospheric poleward moving density enhancements can also form in the absence of changes in the solar wind. This study examines how TOI and patch events that are not triggered by solar wind changes relate to magnetospheric processes, specifically substorms. Based on total electron content and Super Dual Auroral Radar Network (SuperDARN) observations, we find substorms that occur at the same time as TOIs are associated with sudden enhancements in dayside poleward flows during the substorm expansion phase. Active Magnetosphere and Planetary Electrodynamics Response Experiment (AMPERE) observations also show enhanced field‐aligned currents (FACs) that extend into the dayside ionosphere during this period. We suggest that the global enhancement of FACs and convection during these substorms are the drivers of these TOIs by enhancing dayside convection and transporting high‐density lower‐latitude plasma into the polar cap. However, we also find that not all substorms are coincident with polar cap density enhancements. A superposed epoch study showed that the AL index for TOIs during substorms is not particularly stronger than substorms without TOIs, but epoch studies of AMPERE observations do show events with TOIs to have a higher total FAC on both the dayside and nightside. Our results show the importance of TOI formation during substorms when solar wind drivers are absent, and the importance of considering substorms in the global current system. This work also shows the need to incorporate substorms into models of high‐latitude global convection and currents.
Key Points
Enhanced dayside flows without interplanetary magnetic field changes can occur during substorms
Dayside plasma flows during substorms can transport photoionized plasma into the polar cap
Substorms impact dayside currents and patches despite being typically associated with the nightside
Although various license plate location methods have been proposed in the past decades, their accuracy and ability to deal with different types of license plates still need to be improved. A robust ...license plate location method can raise the accuracy of the whole license plate recognition procedure. This paper proposes a robust method based on wavelet transform and empirical mode decomposition (EMD) analysis to search for the location of a license plate in an image to deal with some challenging problems in practice such as illumination changes, complex background and perspective change. By applying wavelet transform on a vehicle image and projecting the acquired details of the image, a wave crest that indicates the license plate will be generated. In order to locate the desired wave crest in the nonlinear and non-stationary projection dataset, EMD analysis is applied. Using the reconstructed projection data and the Hilbert transform of intrinsic mode function components, the position of the license plate is detected. Comprehensive experiments show that this method can locate the positions of various types of license plates with a high accuracy of 97.91% and a relatively short running time.
●A novel license plate location method is proposed.●The proposed method is based on wavelet transform and EMD analysis.●The proposed method can locate different types of license plates under some challenging situations.●The correct detection rate is improved while the runtime is relatively short compared to some traditional approaches.
The "Blue Sky Project" was proposed in 1998 to investigate by how much emissions should be reduced to increase blue sky frequency in Beijing, which hosted the Summer Olympics in 2008. This paper ...focuses on the temporal variation of visibility and its dependence on meteorological conditions and suspended particles at Beijing using the hourly observed visibility data at Beijing Capital International Airport (BCIA) from 1999 to 2007. It has been found that about 47.8% (24.2%) of the hours in Beijing are "bad" ("good") hours with visibility below 10 km (equal or higher than 20 km) between 1999 and 2007. Due to the high Relative Humidity (RH), summer is the season with the lowest mean visibility in a year. Although PM10 index was reported in a decreasing trend (Chan and Yao, 2008), the increase of RH has resulted in a decreasing trend of visibility over BCIA in the summer from 1999 to 2007. To ensure blue sky ("good" visibility) for Olympics 2008, daily mean PM10 index should have been reduced from 81 to 44. This requires that not only vehicle emissions, but also other emissions should be limited. Observations verify that blue-sky-hour rate increased significantly after mean PM10 index was reduced to 53 during Olympics 2008, however, the visibility of 2009 returned to the mean level from 1999 to 2007 during the period 8−24 August. RH (aerosol) contribute 24% (76%) of the improvement of visibility during August 2008.
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•Two chitosan derivatives (CS-PT, CS-PT-Bn) were synthesized as green corrosion inhibitors for carbon steel in acidic environment.•CS-PT and CS-PT-Bn exhibit high inhibitive ...performance with the inhibition efficiencies of 98.4% and 98.5%.•CS-PT and CS-PT-Bn molecules can adsorb on Fe surface in a parallel pattern.•The adsorption mechanism of CS-PT and CS-PT-Bn was explored by theoretical calculations.
Among the biodegradable polysaccharide, chitosan is widely present in the cell membranes of bacteria and algae and in the cell walls of higher plants. As a promising biopolymer, chitosan has great potential as eco-friendly corrosion inhibitor. Herein, two synthetic chitosan derivatives (N-phenylthiourea chitosan (CS-PT), N-phenyl-O-benzylthiourea chitosan (CS-PT-Bn)) were investigated as high-efficient acidic corrosion inhibitors to deal with the corrosion issue of carbon steel. The anti-corrosion property of the chitosan derivatives was explored by electrochemical tests, surface characterization and theoretical calculations. The experimental results indicate that both CS-PT and CS-PT-Bn present high-efficient inhibition performance with the inhibition efficiency of 98.4% and 98.5% at the concentration of 100 mg/L, respectively. Their adsorption mechanism at steel/solution interface is revealed by quantum chemical calculations, molecular dynamics (MD) and GFN-xTB calculations. It is found that CS-PT and CS-PT-Bn adsorb at the steel/solution interface by forming Fe-N and Fe-S bonds. Compared to CS-PT molecule, the introduction of benzyl group endows CS-PT-Bn molecule with stronger electrostatic effect and hydrophobicity, which favors the interfacial adsorption of CS-PT-Bn molecule on carbon steel surface.
The collaborative oscillation of conductive electrons in metal nanoparticles results in a surface plasmon resonance that makes them useful for various applications including biolabeling. We ...investigate the coupling between pairs of elliptical metal particles by simulations and experiments. The results demonstrate that the resonant wavelength peak of two interacting particles is red-shifted from that of a single particle because of near-field coupling. It is also found that the shift decays approximately exponentially with increasing particle spacing and become negligible when the gap between the two particles exceeds about 2.5 times the particle short-axis length.
Dysregulated microRNAs (miRNAs) can serve as oncogenes or suppressors and are associated with many cancers, including oesophageal squamous cell carcinoma (ESCC).
An alignment miRNA array was used to ...identify differentially expressed miRNAs in ESCC tissues. The expression of miR-183 and programmed cell death 4 (PDCD4) in oesophageal tissues from ESCC and early oesophageal carcinoma patients was examined by quantitative reverse transcriptase PCR and western blotting. A luciferase assay was performed to confirm miR-183 target genes. The effects of miR-183 on ESCC cells and the associated mechanisms were established by in vitro experiments.
We identified 51 upregulated miRNAs and 17 downregulated miRNAs in our array, and miR-183 was one of the most upregulated miRNAs. An inverse correlation between miR-183 and PDCD4 levels was found in ESCC tissues. Upregulated expression of miR-183 was not correlated with tumour stage or lymphatic metastasis in ESCC patients. The luciferase assay confirmed that miR-183 directly interacted with the PDCD4 mRNA 3'-untranslated region in ESCC cells. Overexpression of miR-183 led to decreased PDCD4 protein levels and promoted ESCC cell proliferation and invasion. Inhibition of the PI3K/Akt signalling pathway increased PDCD4 protein levels and decreased miR-183 expression in ESCC cells.
MiR-183 promotes ESCC cell proliferation and invasion by directly targeting PDCD4, which suggests that it is involved in the pathogenesis of ESCC.
The Wnt/β-catenin pathway has important roles in chemoresistance and multidrug resistance 1 (MDR1) expression in some cancers, but its involvement in breast cancer and the underlying molecular ...mechanism are undefined. In this study, we demonstrated that the Wnt/β-catenin pathway is activated in chemoresistant breast cancer cells. Using a Wnt pathway-specific PCR array screening assay, we detected that Pygo2, a newly identified Wnt/β-catenin pathway component, was the most upregulated gene in the resistant cells. Additional experiments indicated that Pygo2 activated MDR1 expression in the resistant cells via the Wnt/β-catenin pathway. Moreover, the inhibition of Pygo2 expression restored the chemotherapeutic drug sensitivity of the resistant cells and reduced the breast cancer stem cell population in these cells in response to chemotherapy. Importantly, these activities induced by Pygo2 were mediated by MDR1. We also determined the effect of Pygo2 on the sensitivity of breast tumors resistant to doxorubicin in a mouse model. Finally, RNA samples from 64 paired patient tumors (before and after chemotherapy) highly and significantly overexpressed Pygo2 and/or MDR1 after treatment, thus underlining a pivotal role for the Pygo2-mediated Wnt/β-catenin pathway in the clinical chemoresistance of breast cancer. Our data represent the first implication of the Wnt/β-catenin pathway in breast cancer chemoresistance and identify potential new targets to treat the recurrence of breast cancer.
As one of the most important engineering materials, aluminum alloys have been widely applied in many fields. However, the requirement of enhancing their mechanical properties without sacrificing the ...ductility is always a challenge in the development of aluminum alloys. Thanks to the excellent physical and mechanical properties, graphene nanoflakes (GNFs) have been applied as promising reinforcing elements in various engineering materials, including polymers and ceramics. However, the investigation of GNFs as reinforcement phase in metals or alloys, especially in aluminum alloys, is still very limited. In this study, the aluminum alloy reinforced by GNFs was successfully prepared via powder metallurgy approach. The GNFs were mixed with aluminum alloy powders through ball milling and followed by hot isostatic pressing. The green body was then hot extruded to obtain the final GNFs reinforced aluminum alloy nanocomposite. The scanning electron microscopy and transmission electron microscope analysis show that GNFs were well dispersed in the aluminum alloy matrix and no chemical reactions were observed at the interfaces between the GNFs and aluminum alloy matrix. The mechanical properties׳ testing results show that with increasing filling content of GNFs, both tensile and yield strengths were remarkably increased without losing the ductility performance. These results not only provided a pathway to achieve the goal of preparing high strength aluminum alloys with excellent ductilitybut they also shed light on the development of other metal alloys reinforced by GNFs.
Abstract
We present a statistical study of the ion upflow associated with subauroral polarization streams (SAPS) in the ionospheric subauroral region at different substorm times using three Defense ...Meteorological Satellite Program satellite (F16–F18) data for five years (2010–2014) in the Northern Hemisphere. The results show similarities between SAPS and the ion upflow at different intensity of substorms both in occurrence rate distribution and velocity distribution. In comparison to SAPS, the distribution of the ion upflow shows the smaller occurrence region and lower velocity. We also find that frictional heating plays an important role in ion upflow from the SAPS region. The intense substorms can trigger strong SAPS channels, enhanced frictional heating, and large ion upflow. In addition, there is a moderate linear correlation between SAPS velocity and field‐aligned velocity that is consistent with some previous findings. Our results also show that frictional heating can gradually dominate the ion upflow process in intense substorms, while it may not be the only factor to affect the whole upflow process.
Key Points
Ion upflow is frequently observed near the SAPS flow channel, with similar distributions in the occurrence and velocity as SAPS
Statistical analysis shows that field‐aligned (ion upflow) velocity has moderate linear correlation with SAPS velocity indeed
Frictional heating can gradually dominate the ion upflow process, while it may not be the only factor to affect such process
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