We present an open-source software package WannierTools, a tool for investigation of novel topological materials. This code works in the tight-binding framework, which can be generated by another ...software package Wannier90 (Mostofi et al., 2008). It can help to classify the topological phase of a given material by calculating the Wilson loop, and can get the surface state spectrum, which is detected by angle resolved photoemission (ARPES) and in scanning tunneling microscopy (STM) experiments. It also identifies positions of Weyl/Dirac points and nodal line structures, calculates the Berry phase around a closed momentum loop and Berry curvature in a part of the Brillouin zone (BZ).
Program title:WannierTools
Program Files doi:http://dx.doi.org/10.17632/ygsmh4hyh6.1
Licensing provisions: GNU General Public Licence 3.0
Programming language: Fortran 90
External routines/libraries used:•BLAS (http://www/netlib.org/blas)•LAPACK (http://www.netlib.org/lapack)
Nature of problem: Identifying topological classifications of crystalline systems including insulators, semimetals, metals, and studying the electronic properties of the related slab and ribbon systems.
Solution method: Tight-binding method is a good approximation for solid systems. Based on that, Wilson loop is used for topological phase classification. The iterative Green’s function is used for obtaining the surface state spectrum.
Polymers and polymer composites are susceptible to premature failure due to the formation of cracks and microcracks during their service time. Evolution of cracks and microcracks could induce ...catastrophic material failure. Therefore, the detection/diagnostics and effective repair of cracks and microcracks are vital for ensuring the performance reliability, cost effectiveness and safety for polymer structures. Cracks and microcracks, however, are difficult to detect and often repair processes are complex. Biologically inspired self-healing polymer systems with inherent ability to repair damage have the potential to autonomically repair cracks and microcracks. This article is a review on the latest developments on the topics of cracks and microcracks initiation and propagation in polymer structures and it discusses the current techniques for detection and observation. Furthermore, cracks and microcrack repair through bio-mimetic self-healing techniques is discussed along with surface active protection. A separate section is dedicated to fracture analysis and discusses in details fracture mechanics and formation.
Protein phase separation drives the assembly of membraneless organelles, but little is known about how these membraneless organelles are maintained in a metastable liquid- or gel-like phase rather ...than proceeding to solid aggregation. Here, we find that human small heat-shock protein 27 (Hsp27), a canonical chaperone that localizes to stress granules (SGs), prevents FUS from undergoing liquid-liquid phase separation (LLPS) via weak interactions with the FUS low complexity (LC) domain. Remarkably, stress-induced phosphorylation of Hsp27 alters its activity, leading Hsp27 to partition with FUS LC to preserve the liquid phase against amyloid fibril formation. NMR spectroscopy demonstrates that Hsp27 uses distinct structural mechanisms for both functions. Our work reveals a fine-tuned regulation of Hsp27 for chaperoning FUS into either a polydispersed state or a LLPS state and suggests an essential role for Hsp27 in stabilizing the dynamic phase of stress granules.
There is a strong association between cardiovascular disease (CVD) and periodontitis. This study utilized the Life Essentials 8 (LE8) score, a composite measure of cardiovascular health (CVH), to ...elucidate the relationship between CVH and periodontitis.
Data from 8,649 nationally representative participants in the National Health and Nutrition Examination Survey (NHANES) were analyzed. The independent variable in our study was the CVH score (a higher CVH score indicates better cardiovascular health), and the dependent variable was the presence or absence of periodontitis. The association between CVH and periodontitis was investigated using weighted multivariable logistic regression models and restricted cubic spline (RCS). We controlled for potential confounders such as age, sex, race, education, and socioeconomic status to minimize bias.
There was a negative association between the total CVH score and the odds of periodontitis. After adjusting for all covariates, a 10-point increase in total CVH score was associated with a 10% lower in the odds of periodontitis 0.90 (0.87, 0.93). Participants with a higher CVH had 40% lower odds of periodontitis compared with those with a lower CVH. Socioeconomic status (education and income) modified this association (P for interaction < 0.05).
Our study suggests that better cardiovascular health, as indicated by higher CVH scores, is associated with a reduced likelihood of periodontitis among US adults. The relationship between CVH and periodontitis appears to be influenced by socioeconomic status, emphasizing the need for targeted interventions in populations with lower socioeconomic status.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
In this paper, a three-dimensional visualization model of river water body based on Vega is proposed. This system can not only display the water quality information of each monitoring point on the ...geographic information platform, but also carry out virtual reality roaming of the river. Then the mechanism of interactive allocation of initial water discharge rights is analyzed. According to the principle of interaction and negotiation between different regions and industries, a two-level diagnosis and optimization model is established. Secondly, the optimal equation and diagnostic criteria of comprehensive benefits based on regional economy and society are constructed based on the strict control of the maximum emission permit. The initial emission rights are interactively configured between the primary and secondary levels. Emission reduction targets for each region and industry were proposed. Considering the fairness and effectiveness of the allocation of water discharge rights between regions and industries, the comprehensive benefits of each region and the whole basin are maximized. The feasibility of the scheme is illustrated by an example analysis. It is urgent to carry out the research on the rational allocation of drainage rights in Huaihe River, and the relevant research results will contribute to the sustainable supply of grain in Anhui province, help avoid water disputes around the Huaihe River, and promote the sustainable economic and social development of Anhui province.
•UMSE was firstly applied in extracting process of TMIP and being optimized by RSM.•The extraction yield and purity of TMIP under optimal condition were 35.41% and 73.92%, respectively.•The crude ...TMIP was purified by DEAE-Cellulose 52 and Sephadex G-100 chromatography.•The contents of monosaccharide in TMIP-1, TMIP-2, TMIP-3, and TMIP-4 were different.•The purified TMIP had stronger antioxidation.
Ultrasonic-microwave synergistic extraction (UMSE), purification, and characterization of Tricholoma mongolicum Imai polysaccharides (TMIPs) from fruit bodies were investigated in this study. Response surface methodology (RSM) was employed to optimize the UMSE conditions. The results indicated that the optimal extraction conditions were as follows: extraction time of 24.65min, microwave power of 109.98W, and water to raw material ratio of 21.62ml/g. Under optimized conditions, the yield and purity of TMIPs were 35.41±0.62% and 73.92±0.83%, respectively. Crude TMIPs were purified by DEAE-Cellulose 52 chromatography and Sephadex G-100 chromatography to afford four fractions, namely, TMIP-1, TMIP-2, TMIP-3, and TMIP-4. Preliminary TMIP characterization was conducted by Fourier transform infrared spectroscopy. TMIP antioxidant activities were investigated by measuring its scavenging ability on 2,2-diphenyl-1-picrylhydrazyl, hydroxyl radicals, ferric reducing activity power, and reducing power assay. The results indicated that TMIPs have good antioxidant activity.
Highly skin-conformal wearable tactile sensors with high sensitivity and wide measurement range are promising for physiological signal monitoring, personalized recognition and human-machine ...interaction. In this paper, we report a hybrid piezoelectric-triboelectric sensor (HPTS) primarily composed of polarized micro-frustum-arrays structure lead-zirconate-titanate and polydimethylsiloxane (PZT&PDMS) composite film (m-PZT&PDMS) and m-Cu film, which can simultaneously generate the coupling of piezoelectric effect and triboelectrification by the contact-separation working mode. Combining the hybrid effect, micro-frustum-arrays structure and high piezoelectric constant material, the HPTS presents excellent sensitivity and wide measurement range. The HPTS can reach a sensitivity of 15.43 V/kPa when triboelectric effect performs in the pressure of 0 kPa–100 kPa, and 18.96 V/kPa when both the piezoelectric and triboelectric effects work in the pressure range of 100 kPa–800 kPa. In addition, the HPTS is largely based on the PZT&PDMS film being directly in contact with the skin, showing excellent skin-conformal characteristic. It also demonstrates good linearity, fast response time and high stability. These characteristics are attractive for sensing radial artery wave, monitoring the slide and touch of a finger, and detecting the strong pressure of limb movement. Hence, this work provides a new strategy by applying a highly skin-conformal piezoelectric-enhanced triboelectric nanogenerator with high sensitivity and wide measurement range as a wearable tactile sensor, exhibiting immense potential in medical research, personalized recognition and human-machine interaction.
Based on the contact-separation working mode, the highly skin-conformal piezoelectric-enhanced triboelectric nanogenerator was fabricated with excellent sensitivity (18.96 V/kPa) and wide measurement range (0 kPa–1300 kPa), which presents immense potential in medical research, personalized recognition and human-machine interaction. Display omitted
•Due to the use of m-PZT&PDMS film as the main body, the HPTS is able to provide more conformal and comfortable contact with irregular human skin and withstand complex deformations.•The developed hybrid nanogenerator has high flexibility, excellent sensitivity and wide measurement range.•The polarized m-PZT&PDMS film exhibits excellent output performance because the high piezoelectric modulus of PZT nanofibers, high weight ratio of PZT to PDMS and the optimized polarization parameters.•The highly-conformal HPTS shows the high sensitivity (18.96 V/kPa) and wide measurement range (0 kPa–1,300 kPa) to reliably and simultaneously detect weak and strong external forces in real-time, such as pulse waves and body movements.
In addition to having significant effects on the service life of machined parts, residual stress can cause large deformations during machining of thin-walled parts in aerospace field. The residual ...stress in machined part surface layer is induced by mechanical and thermal stress in the machining process of parts. Therefore, it is essential to accurately predict the generated residual stress due to the machining process. To address this issue, an improved prediction model of the residual stress for orthogonal cutting process based on analytical method is presented by taking the mechanical and thermal stress into consideration. Oxley’s cutting force model and Waldorf’s plowing force model are used to calculate the chip formation force and plowing force based on the contact mechanics, Johnson-Cook constitutive model, and slip line theory. The cutting temperature is predicted according to our previous work based on the Huang-Liang model and the Komanduri-Hou model. The final residual stress is predicted by calculating the loading and relaxation of mechanical and thermal stress. The presented prediction method of residual stress is validated by orthogonal cutting of a Ti6Al4V pipe. It is found that the prediction values of the presented model show a good agreement with the experimental results, which indicates that the presented model can be adopted to predict the residual stress of Ti6Al4V during orthogonal cutting.
Emerging studies demonstrate that long noncoding RNAs (lncRNA) participate in the regulation of various cancers. In the current study, a novel
has been identified and explored in esophageal squamous ...cell carcinoma (ESCC).
To discover a new regulatory circuitry in which RNAs crosstalk with each other, the transcriptome of lncRNA-miRNA-mRNA from ESCC and adjacent nonmalignant specimens were analyzed using multiple microarrays and diverse bioinformatics platforms. The functional role and mechanism of a novel
were further investigated by gain-of-function and loss-of-function assays
and
An ESCC biomarker panel, consisting of
,
, and
, was validated by qRT-PCR and
hybridization using samples from 148 patients.
as an oncogene is highly expressed in ESCC tissues and cell lines, and promotes ESCC cell proliferation and metastasis. Mechanistically,
promotes expression of transcription factor Snail1 by competitively binding
, resulting in the epithelial-mesenchymal transition (EMT) cascade. Moreover,
also induces FSCN1 expression by sponging
and upregulation of mRNA-stabilizing protein HuR, which further promotes ESCC invasion cascades. We also discovered and validated a clinically applicable ESCC biomarker panel, consisting of
,
, and
, that is significantly associated with overall survival and provides additional prognostic evidence for ESCC patients.
As a novel regulator,
plays an important role in ESCC cell proliferation and metastasis. The
regulatory axis provides bona fide targets for anti-ESCC therapies.
.
This paper explored the training methods to improve the level of deaf college students' ToM. Eighty deaf college students were selected as participants and randomly divided into experimental group ...and control group. The ToM training group received ToM training; The non-ToM training group received physical-conversation training. Cognitive ToM task and affective ToM task were used to investigate the training effect. After training, the level of ToM of deaf college students who received ToM training was significantly improved. The results show that ToM training can effectively promote the level of deaf college students' ToM.
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