Municipal solid waste incineration (MSWI) fly ash is considered as a hazardous waste that requires specific treatment before disposal. The principal treatments encompass thermal treatment, ...stabilization/solidification, and resource recovery. To maximize environmental, social, and economic benefits, the development of low-carbon and sustainable treatment technologies for MSWI fly ash has attracted extensive interests in recent years. This paper critically reviewed the state-of-the-art treatment technologies and novel resource utilization approaches for the MSWI fly ash. Innovative technologies and future perspectives of MSWI fly ash management were highlighted. Moreover, the latest understanding of immobilization mechanisms and the use of advanced characterization technologies were elaborated to foster future design of treatment technologies and the actualization of sustainable management for MSWI fly ash.
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•Review the state-of-the-art treatment technologies and recycling approaches for MSWI fly ash.•Compare the merits and demerits of various technologies for MSWI fly ash treatment.•Elaborate the latest immobilization mechanisms based on advanced characterization techniques.•Provide future perspectives for sustainable management of MSWI fly ash.
Legal reform is a method of continuous improvement and promotion of laws. In order to promote legal reform, it is necessary to research and learn about excellent legal reform experiences. The ...People’s Republic of China (PRC) legal reform experience is worth studying and learning about because the PRC has rich reform achievements. There are two important factors contributing to the success of the PRC legal reform. One is that the PRC establishes correct and reasonable legal reform objectives, and the other is that the PRC provides impetuses for legal reform. Therefore, this paper will analyze the above two legal reform experiences to help other countries complete legal reforms.
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•The decoupling state in the upstream reaches has deteriorated.•The decoupling state in the mid and downstream reaches was in a stable weak decoupling state.
China's economic ...development is gradually transforming from an extensive expansion mode to a green development mode that pursues environmental quality and environmental benefits. To achieve economic growth and reduce environmental pollution at the same time is the essence of decoupling. This paper combines the Tapio decoupling model and the Stochastic Impacts by Regression on Population, Affluence, and Technology (STIRPAT) model to analyze the decoupling performance and driving factors of economic output and water environment pressure of provinces and cities in the Yangtze River Economic Belt from 2004 to 2018. The results show that the overall water environment pressure and economic growth of the Yangtze River Economic Belt have shown a positive trend (from weak decoupling to strong decoupling). Strong decoupling areas were identified in the upper reaches of the Yangtze River (Sichuan, Guizhou, Yunnan, and Chongqing), the middle reaches of the Yangtze River (Jiangxi, Hubei, and Hunan), and the lower reaches (Shanghai, Jiangsu, Zhejiang, and Anhui). When compared with decoupling in the middle and lower reaches, the decoupling state of the upper reaches is unstable and tends to deteriorate. The driving factors of water environment pressure indicate that population size and urbanization are the main factors influencing wastewater discharge. The direction and size of the industrial structures are affected by policies and markets. Then, economic growth, fixed asset investment, and trade openness have had a positive impact on wastewater discharge. Technological progress and environmental regulations are important factors in controlling wastewater discharge. However, their current effect on wastewater discharge is not ideal. Therefore, while controlling the reasonable flow of population, each region should carry out industrial optimization and technological upgrading, and increase the management, capital, and technical support for the underdeveloped provinces of the Yangtze Economic Belt. This is necessary to achieve green economic development.
The detection of hydroxyl radical (·OH) in vivo faces challenges as ·OH has short lifetime and low concentration in the body. Fluorescence imaging within the second near-infrared window (NIR-II, ...1000–1700 nm) is a promising approach to in vivo organ and tissue imaging, but ·OH fluorescent probes emitting at this region have not been reported up to now because of the difficulty of probe design. Herein, we report the strategy to fabricate the first NIR-II probe for ·OH by directly breaking/recovering the conjugated system and rigid planar structure of an organic fluorophore, which could regulate the fluorescence intensity regardless of emission wavelength. This activable probe, Hydro-1080, emitted in 1000–1400 nm after responding to ·OH. Hydro-1080 exhibited excellent sensitivity (LOD = 0.5 nM) and selectivity to ·OH. It was able to track subtle variation of ·OH in liver induced by external stimuli and offered clear images with high contrast. This work also indicates that this simple and straightforward strategy can be extended to develop NIR-II fluorescent probes efficiently.
This study presents an integrated methodology that considers renewable distributed generation (RDG) and demand responses (DR) as options for planning distribution systems in a transition towards ...low-carbon sustainability. It is assumed that demand responsiveness is enabled by real-time pricing (RTP), and the problem has been formulated as a dynamic two-stage model. It co-optimizes the allocation of renewables including wind and solar photovoltaic (PV), non-renewable DG units (gas turbines) and smart metering (SM) simultaneously with network reinforcement for minimizing the total economic and carbon-emission costs over planning horizons. The behavior compliance to RTP is described through a nodal-based DR model, in which the fading effect attended during the load recovery is highlighted. Besides, uncertainties associated with renewable energy generation and price-responsiveness of customers are also taken into account and represented by multiple probabilistic scenarios. The proposed methodology is implemented by employing an efficient hybrid algorithm and applied to a typical distribution test system. The results demonstrate the effectiveness in improving the efficiency of RDG operations and mitigating CO 2 footprint of distribution systems, when compared with the conventional planning paradigms.
Routine waterway dredging activities generate huge volumes of dredged sediment. The remediation of dredged contaminated sediment is a worldwide challenge. Novel and sustainable ex-situ remediation ...technologies for contaminated sediment have been developed and adopted in recent years. In this review paper, the state-of-art ex-situ treatment technologies and resource utilisation methods for contaminated sediment were critically reviewed. By applying different techniques, sediment could been successfully transformed into sustainable construction materials, such as ceramsite, supplementary cementitious materials, fill materials, paving blocks, partition blocks, ready-mixed concrete, and foamed concrete. We highlighted that proper remediation technologies should be cleverly selected and designed according to the physical and chemical characteristics of sediment, without neglecting important aspects, such as cost, safety, environmental impacts, readiness level of the technology and social acceptability. The combination of different assessment methods (e.g., environmental impact assessment, cost-benefit analysis, multi-criteria decision analysis and life cycle assessment) should be employed to comprehensively evaluate the feasibility of different sustainable remediation technologies. We call on the scientific community in a multidisciplinary fashion to evaluate the sustainability of various remediation technologies for contaminated sediment.
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•Review the state-of-the-art treatment and recycling technologies for contaminated sediment.•Elaborate immobilisation and removal mechanisms of contaminants in the treated sediment.•Introduce evaluation methods for different ex-situ sediment remediation technologies.•Provide current limitations and future perspectives for sustainable sediment remediation.
This paper critically reviewed the state-of-art ex-situ remediation of contaminated sediment and highlighted the valorisation of sediment into construction materials.
Personalized recommendation plays an important role in many online service fields. In the field of tourism recommendation, tourist attractions contain rich context and content information. These ...implicit features include not only text, but also images and videos. In order to make better use of these features, researchers usually introduce richer feature information or more efficient feature representation methods, but the unrestricted introduction of a large amount of feature information will undoubtedly reduce the performance of the recommendation system. We propose a novel heterogeneous multimodal representation learning method for tourism recommendation. The proposed model is based on two-tower architecture, in which the item tower handles multimodal latent features: Bidirectional Long Short-Term Memory (Bi-LSTM) is used to extract the text features of items, and an External Attention Transformer (EANet) is used to extract image features of items, and connect these feature vectors with item IDs to enrich the feature representation of items. In order to increase the expressiveness of the model, we introduce a deep fully connected stack layer to fuse multimodal feature vectors and capture the hidden relationship between them. The model is tested on the three different datasets, our model is better than the baseline models in NDCG and precision.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
China has a large burden of diabetes: in 2013, one in four people with diabetes worldwide were in China, where 11·6% of adults had diabetes and 50·1% had prediabetes. Many were undiagnosed, ...untreated, or uncontrolled. This epidemic is the result of rapid societal transition that has led to an obesogenic environment against a backdrop of traditional lifestyle and periods of famine, which together puts Chinese people at high risk of diabetes and multiple morbidities. Societal determinants including social disparity and psychosocial stress interact with factors such as low-grade infection, environmental pollution, care fragmentation, health illiteracy, suboptimal self-care, and insufficient community support to give rise to diverse subphenotypes and consequences, notably renal dysfunction and cancer. In the China National Plan for Non-Communicable Disease Prevention and Treatment (2012-15), the Chinese Government proposed use of public measures, multisectoral collaborations, and social mobilisation to create a health-enabling environment and to reform the health-care system. While awaiting results from these long-term strategies, we advocate the use of a targeted and proactive approach to identify people at high risk of diabetes for prevention, and of private-public-community partnerships that make integrated care more accessible and sustainable, focusing on registry, empowerment, and community support. The multifaceted nature of the societal and personal challenge of diabetes requires a multidimensional solution for prevention in order to reduce the growing disease burden.
ADAMTS18 has been identified as an orphan member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family of Zn-dependent secreted metalloproteinases since 2002. Despite ...the recent breakthroughs in tumor biology of ADAMTS18, there is no literature systematically discussing the relationship between ADAMTS18 and cancer. In this review, we will summarize the expression pattern and prognostic value of ADAMTS18 in various cancers. In addition, we will highlight the biological functions of ADAMTS18 in the tumor microenvironment, including the regulation of cell proliferation signals, death patterns, invasion, and migration, which influence cancer progression.
Legumain is required for maintenance of normal kidney homeostasis. However, its role in acute kidney injury (AKI) is still unclear. Here, we induced AKI by bilateral ischemia-reperfusion injury (IRI) ...of renal arteries or folic acid in lgmn
and lgmn
mice. We assessed serum creatinine, blood urea nitrogen, histological indexes of tubular injury, and expression of KIM-1 and NGAL. Inflammatory infiltration was evaluated by immunohistological staining of CD3 and F4/80, and expression of TNF-α, CCL-2, IL-33, and IL-1α. Ferroptosis was evaluated by Acsl4, Cox-2, reactive oxygen species (ROS) indexes H
DCFDA and DHE, MDA and glutathione peroxidase 4 (GPX4). We induced ferroptosis by hypoxia or erastin in primary mouse renal tubular epithelial cells (mRTECs). Cellular survival, Acsl4, Cox-2, LDH release, ROS, and MDA levels were measured. We analyzed the degradation of GPX4 through inhibition of proteasomes or autophagy. Lysosomal GPX4 was assessed to determine GPX4 degradation pathway. Immunoprecipitation (IP) was used to determine the interactions between legumain, GPX4, HSC70, and HSP90. For tentative treatment, RR-11a was administrated intraperitoneally to a mouse model of IRI-induced AKI. Our results showed that legumain deficiency attenuated acute tubular injury, inflammation, and ferroptosis in either IRI or folic acid-induced AKI model. Ferroptosis induced by hypoxia or erastin was dampened in lgmn
mRTECs compared with lgmn
control. Deficiency of legumain prevented chaperone-mediated autophagy of GPX4. Results of IP suggested interactions between legumain, HSC70, HSP90, and GPX4. Administration of RR-11a ameliorated ferroptosis and renal injury in the AKI model. Together, our data indicate that legumain promotes chaperone-mediated autophagy of GPX4 therefore facilitates tubular ferroptosis in AKI.
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