Patterning of upconversion luminescent materials has been widely used for anti-counterfeit and security applications, where the preferred method should be easy, fast, multicolor, high-throughput and ...designable. However, conventional patterning methods are complex and inflexible. Here, we report a digital and flexible inkjet printing based approach for producing high-resolution and high-luminescence anti-counterfeit patterns. We successfully printed different multicolor luminescent patterns by inkjet printing of upconversion nanoparticles with controlled and uniform luminescence intensity through optimizing the inks and substrates. Combined with another downconversion luminescent material, we achieved two different patterns in the same area, which show up separately under excitation by different wavelength laser sources. The developed technology is promising to use one single substrate for carrying abundant information by printing multilayer patterns composed of luminescent materials with different excitation light sources.
•Direct pore-scale modelling of two-phase flow in three-dimensional porous media by VOF method.•The evolution of remaining oil was investigated by considering wettability, viscous force and capillary ...number.•Phase circulation phenomenon was simulated and two circulation patterns were found which can be interconverted.•Preferred conditions for improving the oil recovery rate was discussed in detail.
Characterizing the trapped phase in porous media is essential for many engineering applications, such as enhanced oil recovery, nuclear storage, and geological sequestration of CO2. This study aims to study the distribution, evolution, and influencing factors of the remaining oil in the process of water flooding at the pore scale. The single-connected pore space model was established by reconstructing the real micron CT scanned images of carbonate rocks. The VOF (volume of fluid) method using FSF (filtered surface force) formulation was adopted on OpenFOAM platform to simulate the oil-water two-phase flow process at the pore scale. Different wettability and capillary number were considered in the model. The accuracy of the model was proved by comparing with previous experimental results. The results showed that in the process of water flooding, the complex pore structure would lead to the generation of remaining oil, and the phase circulation phenomenon can be observed in the remaining oil and presents two distribution forms: co-current driven flow and lid-cavity driven flow. It also revealed that the phase recirculation increases the viscous dissipation. Further research also showed that the two forms of recirculation could be transferred by changing the wettability and that a higher capillary number was more beneficial for reducing the remaining oil saturation.
Conspectus Nanofluidics is the study of fluids under nanoscale confinement, where small-scale effects dictate fluid physics and continuum assumptions are no longer fully valid. At this scale, because ...of large surface-area-to-volume ratios, the fluid interaction with boundaries becomes more pronounced, and both short-range steric/hydration forces and long-range van der Waals forces and electrostatic forces dictate fluid behavior. These forces lead to a spectrum of anomalous transport and thermodynamic phenomena such as ultrafast water flow, enhanced ion transport, extreme phase transition temperatures, and slow biomolecule diffusion, which have been the subject of extensive computational studies. Experimental quantification of these phenomena was also enabled by the advent of nanofluidic technology, which has transformed challenging nanoscale fluid measurements into facile optical and electrical recordings. Our groups’ focus is to investigate nanoscale (2 to 103 nm) fluid behaviors in the context of fluid mechanics and thermodynamics through the development of novel nanofluidic tools, to examine the applicability of classical equations at the nanoscale, to identify the source of deviations, and to explore new physics emerging at this scale. In this Account, we summarize our recent findings regarding liquid transport, vaporization, and condensation of nanoscale-confined liquids. Our study of nanoscale water transport identified an additional resistance in hydrophilic nanochannels, attributed to the reduced cross-sectional area caused by the formation of an immobile hydration layer on the surfaces. In contrast, a reduction in flow resistance was discovered in graphene-coated hydrophobic nanochannels, due to water slippage on the graphene surface. In the context of vaporization, the kinetic-limited evaporation flux was measured and found to exceed the classical theoretical prediction by an order of magnitude in hydrophilic nanochannels/nanopores as a result of the thin film evaporation outside of the apertures. This factor was eliminated by modifying the hydrophobicity of the aperture’s exterior surface, enabling the identification of the true kinetic limits inside nanoconfinements and a crucial confinement-dependent evaporation coefficient. The transport-limited evaporation dynamics was also quantified, where experimental results confirmed the parallel diffusion–convection resistance model in both single nanoconduits and nanoporous systems at high accuracy. Furthermore, we have extended our studies to different aspects of condensation in nanoscale-confined spaces. The initiation of condensation for a single-component hydrocarbon was observed to follow the Kelvin equation, whereas for hydrocarbon mixtures it deviated from classical theory because of surface-selective adsorption, which has been corroborated by simulations. Moreover, the condensation dynamics deviates from the bulk and is governed by either vapor transport or liquid transport depending on the confinement scale. Overall, by using novel nanofluidic devices and measurement strategies, our work explores and further verifies the applicability of classical fluid mechanics and thermodynamic equations such as the Navier–Stokes, Kelvin, and Hertz–Knudsen equations at the nanoscale. The results not only deepen our understanding of the fundamental physical phenomena of nanoscale fluids but also have important implications for various industrial applications such as water desalination, oil extraction/recovery, and thermal management. Looking forward, we see tremendous opportunities for nanofluidic devices in probing and quantifying nanoscale fluid thermophysical properties and more broadly enabling nanoscale chemistry and materials science.
Angiogenesis is a necessary process for solid tumor growth. Cellular markers for endothelial cell proliferation are potential targets for identifying the vasculature of tumors in homeostasis. Here we ...customize the behaviors of engineered cells to recognize Apj, a surface marker of the neovascular endothelium, using synthetic Notch (synNotch) receptors. We designed apelin-based synNotch receptors (AsNRs) that can specifically interact with Apj and then stimulate synNotch pathways. Cells engineered with AsNRs have the ability to sense the proliferation of endothelial cells (ECs). Designed for different synNotch pathways, engineered cells express different proteins to respond to angiogenic signals; therefore, angiogenesis can be detected by cells engineered with AsNRs. Furthermore, T cells customized with AsNRs can sense the proliferation of vascular endothelial cells. As solid tumors generally require vascular support, AsNRs are potential tools for the detection and therapy of a variety of solid tumors in adults.
Mechanical signals such as pressure and strain reflect important psychological and physiological states of the human body. Body‐integrated sensors, including skin‐mounted and surgically implanted ...ones, allow personalized health monitoring for the general population as well as patients. However, the development of such measuring devices has been hindered by the strict requirements for human‐biocompatible materials and the need for high performance sensors; most existing devices or sensors do not meet all the desired specifications. Here, a set of flexible, stretchable, wearable, implantable, and degradable mechanical sensors is reported with excellent mechanical robustness and compliance, outstanding biocompatibility, remotely‐triggered degradation, and excellent sensing performance, using a conductive silk fibroin hydrogel (CSFH). They can detect multiple mechanical signals such as pressure, strain, and bending angles. Moreover, combined with a drug‐loaded silk‐based microneedle array, sensor‐equipped devices are shown to be effective for real‐time monitoring and in situ treatment of epilepsy in a rodent model. These sensors offer potential applications in custom health monitoring wearables, and in situ treatment of chronic clinical disorders.
A set of controlled degradable mechanical sensors are developed using carbon nanotubes‐doped conductive silk hydrogels. The sensors can real‐time monitor external forces such as pressure, tension, and bending by sensing the forces‐induced resistance change of their carbon nanotube networks, and simultaneously control drug release through laser radiation‐triggered rapid degradation of the hydrogel‐based sensors for in situ chronic disorders treatment.
In order to ensure the information security, most of the important information including the data of advanced metering infrastructure (AMI) in the energy internet is currently transmitted and ...exchanged through the intranet or the carrier communication. The former increases the cost of network construction, and the latter is susceptible to interference and attacks in the process of information dissemination. The blockchain is an emerging decentralized architecture and distributed computing paradigm. Under the premise that these nodes do not need mutual trust, the blockchain can implement trusted peer-to-peer communication for protecting the important information by adopting distributed consensus mechanisms, encryption algorithms, point-to-point transmission and smart contracts. In response to the above issues, this paper firstly analyzes the information security problems existing in the energy internet from the four perspectives of system control layer, device access, market transaction and user privacy. Then blockchain technology is introduced, and its working principles and technical characteristics are analyzed. Based on the technical characteristics, we propose the multilevel and multichain information transmission model for the weak centralization of scheduling and the decentralization of transaction. Furthermore, we discuss that the information transmission model helps solve some of the information security issues from the four perspectives of system control, device access, market transaction and user privacy. Application examples are used to illustrate the technical features that benefited from the blockchain for the information security of the energy internet.
Induced pluripotent stem cells (iPS cells) are promising cell source for stem cell replacement strategy applied to brain injury caused by traumatic brain injury (TBI) or stroke. Neural stem cell ...(NSCs) derived from iPS cells could aid the reconstruction of brain tissue and the restoration of brain function. However, tracing the fate of iPS cells in the host brain is still a challenge. In our study, iPS cells were derived from skin fibroblasts using the four classic factors Oct4, Sox2, Myc, and Klf4. These iPS cells were then induced to differentiate into NSCs, which were incubated with superparamagnetic iron oxides (SPIOs) in vitro. Next, 30 TBI rat models were prepared and divided into three groups (n = 10). One week after brain injury, group A&B rats received implantation of NSCs (labeled with SPIOs), while group C rats received implantation of non-labeled NSCs. After cell implantation, all rats underwent T2*-weighted magnetic resonance imaging (MRI) scan at day 1, and 1 week to 4 weeks, to track the distribution of NSCs in rats’ brains. One month after cell implantation, manganese-enhanced MRI (ME-MRI) scan was performed for all rats. In group B, diltiazem was infused during the ME-MRI scan period. We found that (1) iPS cells were successfully derived from skin fibroblasts using the four classic factors Oct4, Sox2, Myc, and Klf4, expressing typical antigens including SSEA4, Oct4, Sox2, and Nanog; (2) iPS cells were induced to differentiate into NSCs, which could express Nestin and differentiate into neural cells and glial cells; (3) NSCs were incubated with SPIOs overnight, and Prussian blue staining showed intracellular particles; (4) after cell implantation, T2*-weighted MRI scan showed these implanted NSCs could migrate to the injury area in chronological order; (5) the subsequent ME-MRI scan detected NSCs function, which could be blocked by diltiazem. In conclusion, using an in vivo MRI tracking technique to trace the fate of iPS cells-induced NSCs in host brain is feasible.
The Dongsheng gas field is a water-bearing tight gas reservoir characterized by high connate water saturation. During gas production, the transformation of connate water into movable water introduces ...a unique water production mode, significantly impacting gas reservoir recovery. Current experimental and theoretical methods for assessing formation water mobility are static and do not address the transformation mechanism from connate into movable water. In this study, we considered dynamic changes in formation stress and proposed the mechanism for the transformation of connate water into movable water during depressurization, involving the expansion of connate water films and the reduction of pore volume. We developed a novel methodology to calculate the dynamic changes in movable and connate water saturation in tight reservoirs due to reservoir pressure reduction. Furthermore, we quantitatively evaluated the transformation of connate water into movable water in the Dongsheng gas field through laboratory experiments (including formation water expansion tests, connate water tests, and porosity stress sensitivity tests) and theoretical calculations. Results show that under original stress, the initial connate water saturation in the Dongsheng gas field ranges from 50.09% to 58.5%. As reservoir pressure decreases, the maximum increase in movable water saturation ranges from 6.1% to 8.4% due to the transformation of connate water into movable water. This explains why formation water is produced in large quantities during gas production. Therefore, considering the transition of connate water to movable water is crucial when evaluating water production risk. These findings offer valuable guidance for selecting optimal well locations and development layers to reduce reservoir water production risks.
Bubble nucleation and growth in nanochannels Bao, Bo; Zandavi, Seyed Hadi; Li, Huawei ...
Physical chemistry chemical physics : PCCP,
03/2017, Letnik:
19, Številka:
12
Journal Article
Recenzirano
We apply micro- and nanofluidics to study fundamental phase change behaviour at nanoscales, as relevant to shale gas/oil production. We investigate hydrocarbon phase transition in sub-100 nm channels ...under conditions that mimic the pressure drawdown process. Measured cavitation pressures are compared with those predicted from the nucleation theory. We find that cavitation pressure in the nanochannels corresponds closer to the spinodal limit than that predicted from classical nucleation theory. This deviation indicates that hydrocarbons remain in the liquid phase in nano-sized pores under pressures much lower than the saturation pressure. Depending on the initial nucleation location - along the channel or at the end - two types of bubble growth dynamics were observed. Bubble growth was measured experimentally at different nucleation conditions, and results agree with a fluid dynamics model including evaporation rate, instantaneous bulk liquid velocity, and bubble pressure. Collectively these results demonstrate, characterize, and quantify isothermal bubble nucleation and growth of a pure substance in nanochannels.
During hydraulic fracturing of waxy shale oil reservoirs, the presence of fracturing fluid can influence the phase behavior of the fluid within the reservoir, and heat exchange between the fluids ...causes wax precipitation that impacts reservoir development. To investigate multiscale fluid phase transition and microscale flow impacted by fracturing fluid injection, this study conducted no-water phase behavior experiments, water injection wax precipitation experiments, and water-condition phase behavior experiments using a nanofluidic chip model. The results show that in the no-water phase experiment, the gasification occurred first in the large cracks, while the matrix throat was the last, and the bubble point pressure difference between the two was 12.1 MPa. The wax precipitation phenomena during fracturing fluid injection can be divided into granular wax in cracks, flake wax in cracks, and wax precipitation in the matrix throat, and the wax mainly accumulated in the microcracks and remained in the form of particles. Compared with the no-water conditions, the large cracks and matrix throat bubble point in the water conditions decreased by 6.1 MPa and 3.5 MPa, respectively, and the presence of the water phase reduced the material occupancy ratio at each pore scale. For the smallest matrix throat, the final gas occupancy ratio under the water conditions decreased from 32% to 24% in the experiment without water. This study provides valuable insight into reservoir fracture modification and guidance for the efficient development of similar reservoirs.
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