Disulfiram is used commonly as reinforcement in the treatment of chronic alcoholism. Although the drug is generally considered safe, there are reports of side effects including psychosis and ...hepatitis. We report a case of fatal fulminant hepatitis caused by the use of disulfiram in a man with previously normal hepatocellular function.
Hyperintense cirrhotic nodules on MRI Koslow, S A; Davis, P L; DeMarino, G B ...
Gastrointestinal radiology,
12/1991, Letnik:
16, Številka:
4
Journal Article
Descriptions of regenerating nodules of cirrhosis indicate that they are often isointense to liver parenchyma on magnetic resonance imaging (MRI). Regenerating nodules of cirrhosis can occasionally ...appear hypointense on all MRI sequences due to iron deposition within the nodules. We reviewed 21 cases of pathologically proven mixed or macronodular cirrhosis using MRI. In five patients, nodules appeared as hyperintense to liver parenchyma on short TR/TE images and were isointense on long TR/TE or GRASS images. In another five cases, nodules appeared hypointense on either long TR/TE or GRASS images, and corresponding hypointense nodules were observed on short TR/TE images in one of these patients. Our findings suggest that regenerating nodules of cirrhosis may have a more variable appearance on short TR/TE images.
Endocrine function after cimetidine Fuentes, Jr, R J; Dolinsky, D
The New England journal of medicine,
08/1979, Letnik:
301, Številka:
9
Journal Article
A neuropsychiatric study of individuals who underwent successful liver transplantation an average of 3 years previously was conducted to assess quality of life in terms of cognitive capacity and ...psychiatric status, as well as social and behavioral functioning. Compared with a control group of patients with Crohn's disease, liver transplant patients did not differ on measures of intelligence, language, attention, concentration, spatial organization, memory, or learning. Performance on these diverse aspects of cognitive functioning was in the normal ranges for both groups when compared with normative or standardized test values. The control and liver transplant patients were not different from each other on measures of psychiatric status or social functioning; however, both groups exhibited some disruption of functioning in these two areas when contrasted with normative values. We conclude that relatively young individuals (mean age in this study, 27.8 years) do not exhibit debilitating long-term neuropsychiatric disability after liver transplantation, although some disturbance in social and psychiatric adjustment was observed.
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