We evaluated subpopulations of T-lymphocytes by using the monoclonal antibodies OKT3, OKT4 and OKT8 in two groups of psoriatic patients, with active and stable psoriasis respectively. Whereas data ...from the patients with stable psoriasis were similar to those obtained from the control group, the patients in an acute flare condition revealed a relative decrease in lymphocytes reactive with OKT8, and a slight increase in the proportion of lymphocytes reactive with OKT4. The results of this study are analysed.
Olindias sambaquiensis, Muller 1861 (Hydrozoa: Limnomedusae: Olindiidae) is a neritic jellyfish endemic in the Blanca Bay area (South of Buenos Aires, Argentina). In this paper we describe the first ...report of a dermatitis caused by this jellyfish in a thirty-four-year-old marine biologist who presented with an erythematous vesicular eruption after contact with Olindias sambaquiensis. Some preliminary ultramicroscopic observations on the nematocysts of this jellyfish are also reported.
Cyclosporin A (CyA) is a very effective immunosuppressor for inhibition of the humoral immune response and especially for cell mediation and was originally indicated for transplantation of organs and ...autoimmune diseases. More recently, CyA has been used successfully for severe psoriasis. In this study, the authors describe the results obtained from 8 patients who presented with a psoriatic arthropathy, treated with small doses of CyA (3-5 mg/kg/day). There were reactions in five of them, in two patients the Ritchie index decreased moderately and in one patient the arthritic psoriasis was significantly improved.
A young man had persistent hyperpigmentation on the face following a jellyfish (Pelagia noctiluca) sting four years previously. This localized lesion resolved within forty days after topical ...hydroquinone (1.8 percent) therapy was instituted. This case is presented to demonstrate that persistent hyperpigmentation occurring after coelenterate stings can be treated with a topical bleaching agent.
Between 1987 and 1991, the authors made patch-tests on 1,427 patients, 389 male and 1,038 female, of mean age 36 years (6-70 years) and mostly suffering from eczema. The standard tests of Italian ...Group for Research into Contact Dermatitis and the Environment (GIRDCA) were used, following the best data of recent years. Nickel sulphate, thiomersal, "Fragrance mix", cobalt sulphate and potassium bichromate were the allergens varied with age: nickel and thiomersal were most frequently positive between 20 and 30 years. In contrast, the highest frequency of positivity to fragrance mix was seen between 40 and 60 years. Positivity to a simple allergen had a tendancy to reduce with age.
