Over the past 13 years mitochondrial defects have been involved in wide variety of degenerative diseases - Parkinson disease, Alzheimer dementia, arteriosclerosis, ageing and cancer. Mitochondria are ...believed to control apoptosis or programmed cell death. Disturbance in mitochondrial metabolism has also been implicated in many common diseases such as congestive hart failure, diabetes and migraine. Scientific investigations have showed complexities in mitochondrial genetics, but at the same time, pathophysiology of mitochondrial diseases is still enigma. Mitochondria and their DNAs are opening the era of "mitochondrial medicine". What we today call "a mitochondrial medicine" is only a part of the whole panorama of diseases based on disordered mitochondrial function.
Serum angiotensin-converting enzyme was measured in 60 patients with endemic nephropathy and in 30 healthy individuals. According to the arterial blood pressure, the patients with endemic nephropathy ...were further divided into groups with arterial hypertension (n = 30) and without arterial hypertension (n = 30). The activity of angiotensin-converting enzyme was determined by a spectrophotometric method using hippuryl-l-histidyl-l-leucine as a substrate. The serum activity of angiotensin-converting enzyme was significantly increased in the patients with endemic nephropathy (28.51 +/- 1.64 U/l) as compared with healthy individuals (20.83 +/- 1.33 U/l). The level of the enzyme was further increased if the endemic nephropathy was accompanied by arterial hypertension (37.09 +/- 1.45 U/l). The possible mechanisms of the increase in the angiotensin-converting enzyme activity are discussed.
Nauka, a ne politika Kulenović, Husein
Gračanički glasnik : časopis za kulturnu istoriju Gračanice i njene okoline,
1998
5
Journal Article
Odprti dostop
Ako se čovjek vec odluči da donosi i stvara zaključke ili sudove o suštin i i svjetonazoru drugog, podjednako i dosljedno mora potisnuti interese egoistične i moralne naravi, kako svoje, tako i ...njegove. Ne učini li taj esencijalni ustupak, tegoban je i isprazan posao moralisati, uznositi ili razudivati i unižavati plodove mislenih radnji i njihovog konačnog izražaja, pogotovo nekog predanog potrebi definiranja linije vodilje životnih određenja i vjerovanja.
The war injuries are the most frequent multiple, with the difficult distructions of the tissue and the lesions of the peripheral nerves. By the injuries, the lesions of the nerv system represent the ...delicate problem for the physical medicine and the rehabilitation during the siege of Sarajevo (1992-1995), in the injuries with the lesions of the peripheral nerves, if they are not treated in the frame of the multiple las urgent, they are postponed the operative treatments longer than three months. This is from the aspect of the successfullness, prognostically and therapeutically, the limiting moment. The successfullness of the operative treatment of the lesions of the peripheral nerves significantly depends on that whether the operation was performed incide tree months. The more difficult consequences in these injuries can appear if simultaneously with the taking care of war injuries does not perform adequately surgical treatment adn the in time physical therapy trough the sufficient long time period. On the four year sample was analyzed the success fullness of the rehabilitation of the injuries of the upper extremities with the lesions of the peripheral nerves. Clinically, uniform, we valorized the success fullness of the treatment of all the patients by the marks from 0.5. In the complete sample the excellent success of the rehabilitation we confirmed in more than a half of patients. The better results show the group of the operated patients, in which is performed neuropathia or neurolisis. The capability of the regeneration of the injured peripheral nerves offers the real possibility for extraordinary recovery also in the most difficult injuries, then the preventions of the significant number of the consequences.
In this paper is valoriziaed the successfulness of the treatment of 1,431 patients with the verification disc hernia (CT, MRI) in the surgery for the physical medicine and the rehabilitation in the ...period from 1966 till 2000 year, by "Praxis method". It is established that in the structure of the treated patients by the structure of the treated patients by the application of this method the best results were achieved by disc hernia in the level L4-L5 without the motor deficiency (567 patients), with the average treatment length 24.38 days and the average estimation of the results 4.06 and then in patients with the disc hernia L5-S1. In disc hernia without diagnostic verified disorder of the motorics, the result of the physical therapy and the rehabilitation was better. This can be observed from the treatment successfulness estimation and the treatment length and number of days of the treatment. The longest treatment was by hernia L5-S1 with the motor disorderly (43.10 days), and the shortest in the disc lesion at the level L4-L5 (24.38 days). Among the patients with disc hernia which in this period were treated was operated only 58 or 4.05%. The age structure of the treated patients with disc hernia amounted averagelly 49.95 years, and the greatest number of the treated belonged to the age group 35 to 44 years.
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