This book examines the protection against refoulement under the European Convention on Human Rights and the UN Convention against Torture. It provides a comprehensive and comparative analysis of the ...non-refoulement case-law of both the European Court of Human Rights and the UN Committee against Torture.
Studies the cultural texts--fiction, protest effigies, photographs, films, reportage, eyewitness accounts, campaign posters and reports--produced around the world's worst industrial disaster: the ...Bhopal tragedy of 1984. It makes a case for an ecological perspective, wherein the city, its landscape and its people are Gothicized. After presenting the history of the disaster in terms of negligence, the book examines the coverage of the events as well as accounts by eyewitnesses and survivors, and the remnants, in various forms, of the disaster - the haunting - within human bodies and nature. Finally,Bhopal's Ecological Gothic describes the industrial ruins and the mobilization of protests against Union Carbide.
O presente artigo apresenta uma contextualização do cenário brasileiro de 2020, em meio a mais grave pandemia dos últimos 100 anos, à luz da obra distópica 1984 de George Orwell, ficção sobre um ...futuro totalitário e opressor, publicada em 1949. Buscou-se elencar elementos da obra que apontam similaridades com o caso brasileiro, como a evocação de uma narrativa de ódio a opositores, gestão executiva destoando de sua missão institucional, uso deliberado de inverdades colocadas a público. As peças de acusação Dois Minutos de Ódio; Os Anti-ministérios e o Falseamento da verdade, extraídas de 1984, buscam expor tais similaridades.
The diagnosis of Alzheimer's disease can be improved by the use of biological measures. Biomarkers of functional impairment, neuronal loss, and protein deposition that can be assessed by neuroimaging ...(ie, MRI and PET) or CSF analysis are increasingly being used to diagnose Alzheimer's disease in research studies and specialist clinical settings. However, the validation of the clinical usefulness of these biomarkers is incomplete, and that is hampering reimbursement for these tests by health insurance providers, their widespread clinical implementation, and improvements in quality of health care. We have developed a strategic five-phase roadmap to foster the clinical validation of biomarkers in Alzheimer's disease, adapted from the approach for cancer biomarkers. Sufficient evidence of analytical validity (phase 1 of a structured framework adapted from oncology) is available for all biomarkers, but their clinical validity (phases 2 and 3) and clinical utility (phases 4 and 5) are incomplete. To complete these phases, research priorities include the standardisation of the readout of these assays and thresholds for normality, the evaluation of their performance in detecting early disease, the development of diagnostic algorithms comprising combinations of biomarkers, and the development of clinical guidelines for the use of biomarkers in qualified memory clinics.
O presente artigo se propõe a analisar a constituição e estrutura da Autoridade Nacional de Proteção de Dados a fim de discutir os riscos da interferência política na atuação da ANPD brasileira, em ...meio ao contexto de vigilância na sociedade de informação e em paralelo com a obra literária 1984, de George Orwell. Utilizando esse horizonte distópico como pano de fundo para demonstrar o impacto da atuação política do Estado no exercício da vigilância, recorreu-se a uma abordagem qualitativa, elaborada a partir de pesquisa bibliográfica e documental, para, ao final, concluir que, a ingerência política permitida pela estrutura institucional da ANPD brasileira é prejudicial à sua autonomia funcional, comprometendo a eficácia da Lei Geral de Proteção de Dados e possibilitando a existência de uma sociedade vigiada, comparável à narrativa distópica em cotejo.
We estimated the age-specific duration of the preclinical, prodromal, and dementia stages of Alzheimer's disease (AD) and the influence of sex, setting, apolipoprotein E (APOE) genotype, and ...cerebrospinal fluid tau on disease duration.
We performed multistate modeling in a combined sample of 6 cohorts (n = 3268) with death as the end stage and estimated the preclinical, prodromal, and dementia stage duration.
The overall AD duration varied between 24 years (age 60) and 15 years (age 80). For individuals presenting with preclinical AD, age 70, the estimated preclinical AD duration was 10 years, prodromal AD 4 years, and dementia 6 years. Male sex, clinical setting, APOE ε4 allele carriership, and abnormal cerebrospinal fluid tau were associated with a shorter duration, and these effects depended on disease stage.
Estimates of AD disease duration become more accurate if age, sex, setting, APOE, and cerebrospinal fluid tau are taken into account. This will be relevant for clinical practice and trial design.
•First age-specific estimates of the duration of AD, including predementia stages.•Overall AD duration ranged from 24 years at age 60 to 15 years at age 80.•Preclinical AD stage was much shorter in a clinical setting than a research setting.•Females had a longer dementia duration.•APOE ɛ4 and CSF tau abnormality shortened the preclinical and prodromal AD stages.
Oligarchical collectivism that supports totalitarianism silences freedom of speech, privacy, assembly, etc. both personal and communal through horrific pain or plentiful pleasure. Authors write ...literary works to remind readers of this situation through novels, poems, plays, political essays, and or satire. In today's life, it seems these two ways of totalitarianism are being practiced in life singly or combined in different parts of the world. This can be seen in a number of countries where the government does this both in disguise and addressed to a certain group of members of society such as in Nigeria and in real terms such as in Nicaragua. This is also done in total for a country such as Ukraine by Russia. Two of those great anti-utopia literary works are novels that raise the issue of restrained freedom of life in Huxley's Brave New World and Orwell's 1984. These two anti-utopian novels raise the issue of the freedom of life that is confined but in different ways. Using Marxist psychoanalytic criticism, this paper discusses this issue seen in both novels by the two authors. The focus is on how both authors show totalitarianism being practiced both personally, and in the society found in these novels – how they are treated to follow rules that confine personal and societal freedom in totalitarianism.
News Shocks under Financial Frictions Görtz, Christoph; Tsoukalas, John D.; Zanetti, Francesco
American economic journal. Macroeconomics,
10/2022, Letnik:
14, Številka:
4
Journal Article
Recenzirano
Odprti dostop
We examine the dynamic effects of TFP news shocks in the context of frictions in financial markets. We document two new facts. First, a shock to future TFP generates a significant decline in credit ...spread indicators along with a robust improvement in credit supply indicators. Second, we establish a tight link between TFP news shocks and shocks that explain the majority of un-forecastable movements in credit spread indicators. A DSGE model enriched with a financial sector of the Gertler-Kiyotaki-Karadi type generates very similar quantitative dynamics. (JEL E12, E31, E32, E44, G12, G21)
Although India and China have very different experiences of colonialism, they respond to that history in a similar way-by treating it as a collective trauma. As a result they have a strong sense of ...victimization that affects their foreign policy decisions even today.
Wronged by Empire breaks new ground by blending this historical phenomenon, colonialism, with mixed methods-including archival research, newspaper data mining, and a new statistical method of content analysis-to explain the foreign policy choices of India and China: two countries that are continuously discussed but very rarely rigorously compared. By reference to their colonial past, Manjari Chatterjee Miller explains their puzzling behavior today. More broadly, she argues that the transformative historical experience of a large category of actors-ex-colonies, who have previously been neglected in the study of international relations-can be used as a method to categorize states in the international system. In the process Miller offers a more inclusive way to analyze states than do traditional theories of international relations.