In nineteenth-century America, the belief that blacks and whites could not live in social harmony and political equality in the same country led to a movement to relocate African Americans to ...Liberia, a West African colony established by the United States government and the American Colonization Society in 1822. InThe Price of Liberty, Claude Clegg accounts for 2,030 North Carolina blacks who left the state and took up residence in Liberia between 1825 and 1893. By examining both the American and African sides of this experience, Clegg produces a textured account of an important chapter in the historical evolution of the Atlantic world.For almost a century, Liberian emigration connected African Americans to the broader cultures, commerce, communication networks, and epidemiological patterns of the Afro-Atlantic region. But for many individuals, dreams of a Pan-African utopia in Liberia were tempered by complicated relationships with the Africans, whom they dispossessed of land. Liberia soon became a politically unstable mix of newcomers, indigenous peoples, and "recaptured" Africans from westbound slave ships. Ultimately, Clegg argues, in the process of forging the world's second black-ruled republic, the emigrants constructed a settler society marred by many of the same exclusionary, oppressive characteristics common to modern colonial regimes.
The aim of this study is to estimate the immediate and lasting effects of the 2014-2015 Ebola virus disease (EVD) outbreak on public-sector primary healthcare delivery in Liberia using 7 years of ...comprehensive routine health information system data.
We analyzed 10 key primary healthcare indicators before, during, and after the EVD outbreak using 31,836 facility-month service outputs from 1 January 2010 to 31 December 2016 across a census of 379 public-sector health facilities in Liberia (excluding Montserrado County). All indicators had statistically significant decreases during the first 4 months of the EVD outbreak, with all indicators having their lowest raw mean outputs in August 2014. Decreases in outputs comparing the end of the initial EVD period (September 2014) to May 2014 (pre-EVD) ranged in magnitude from a 67.3% decrease in measles vaccinations (95% CI: -77.9%, -56.8%, p < 0.001) and a 61.4% decrease in artemisinin-based combination therapy (ACT) treatments for malaria (95% CI: -69.0%, -53.8%, p < 0.001) to a 35.2% decrease in first antenatal care (ANC) visits (95% CI: -45.8%, -24.7%, p < 0.001) and a 38.5% decrease in medroxyprogesterone acetate doses (95% CI: -47.6%, -29.5%, p < 0.001). Following the nadir of system outputs in August 2014, all indicators showed statistically significant increases from October 2014 to December 2014. All indicators had significant positive trends during the post-EVD period, with every system output exceeding pre-Ebola forecasted trends for 3 consecutive months by November 2016. Health system outputs lost during and after the EVD outbreak were large and sustained for most indicators. Prior to exceeding pre-EVD forecasted trends for 3 months, we estimate statistically significant cumulative losses of -776,110 clinic visits (95% CI: -1,480,896, -101,357, p = 0.030); -24,449 bacille Calmette-Guérin vaccinations (95% CI: -45,947, -2,020, p = 0.032); -9,129 measles vaccinations (95% CI: -12,312, -5,659, p < 0.001); -17,191 postnatal care (PNC) visits within 6 weeks of birth (95% CI: -28,344, -5,775, p = 0.002); and -101,857 ACT malaria treatments (95% CI: -205,839, -2,139, p = 0.044) due to the EVD outbreak. Other outputs showed statistically significant cumulative losses only through December 2014, including losses of -12,941 first pentavalent vaccinations (95% CI: -20,309, -5,527, p = 0.002); -5,122 institutional births (95% CI: -8,767, -1,234, p = 0.003); and -45,024 acute respiratory infections treated (95% CI: -66,185, -24,019, p < 0.001). Compared to pre-EVD forecasted trends, medroxyprogesterone acetate doses and first ANC visits did not show statistically significant net losses. ACT treatment for malaria was the only indicator with an estimated net increase in system outputs through December 2016, showing an excess of +78,583 outputs (95% CI: -309,417, +450,661, p = 0.634) compared to pre-EVD forecasted trends, although this increase was not statistically significant. However, comparing December 2013 to December 2017, ACT malaria cases have increased 49.2% (95% CI: 33.9%, 64.5%, p < 0.001). Compared to pre-EVD forecasted trends, there remains a statistically significant loss of -15,144 PNC visits within 6 weeks (95% CI: -29,453, -787, p = 0.040) through December 2016.
The Liberian public-sector primary healthcare system has made strides towards recovery from the 2014-2015 EVD outbreak. All primary healthcare indicators tracked have recovered to pre-EVD levels as of November 2016. Yet, for most indicators, it took more than 1 year to recover to pre-EVD levels. During this time, large losses of essential primary healthcare services occurred compared to what would have been expected had the EVD outbreak not occurred. The disruption of malaria case management during the EVD outbreak may have resulted in increased malaria cases. Large and sustained investments in public-sector primary care health system strengthening are urgently needed for EVD-affected countries.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Diamondiferous rock types worldwide are broadly divided into kimberlite and lamproite, the latter of which have unique characteristics in different regions and include carbonate-rich varieties ...(formerly orangeites/Group II kimberlites). Diamondiferous rocks in West Africa are typically micaceous and share petrographic, mineralogical, and geochemical characteristics with both kimberlites and lamproites. To further constrain the classification and petrogenesis of diamondiferous rocks worldwide and their variability between different cratonic regions, in this study we combine detailed petrographic observations with olivine, phlogopite, and spinel chemistry for hypabyssal samples from the Jurassic Tongo dike (Sierra Leone) and the Neoproterozoic Weasua cluster (Liberia).
The Tongo dike contains macrocrysts of olivine and phlogopite in a groundmass of olivine, abundant phlogopite, spinel, perovskite, and apatite with a base of calcite, dolomite, and lesser serpentine. The phlogopite is characterised by concurrent FeO and Al2O3 enrichment, which is typical of kimberlites and unlike lamproites. These features and the kimberlite-like spinel compositions allow us to classify the Tongo samples as micaceous kimberlites. The Weasua rocks comprise macrocrysts of olivine in a groundmass of olivine, phlogopite, diopside (zoned towards aegirine-rich rims), spinel, perovskite, and apatite with a base of serpentine and less common calcite. The composition of Weasua phlogopite trends to significant FeO enrichment and Al2O3 depletion, i.e. towards tetraferriphlogopite. The enrichment in mica, phlogopite chemistry and presence of magmatic diopside indicates that these rocks are olivine lamproites.
The populations of olivine macrocrysts and microcrysts at Tongo and Weasua are similar and characterised by distinct core and rim zones. Two distinct olivine core populations are observed. 1) forsterite-rich (Fo > 90) olivine interpreted to reflect xenocrysts from typical mantle peridotites. Al-in-olivine thermometry suggests that these cores have P-T equilibration within diamond stability at Weasua and Tongo. 2) Al-, Ca- and Na- rich cores with P-T formation conditions extending beyond the mantle adiabat. These cores are interpreted to reflect metasomatic and thermal perturbation linked with the infiltration of kimberlite/lamproite melts in the deep lithosphere shortly before entrainment in the ascending magma. The olivine rims at Tongo and Weasua show limited variations in Fo contents at similar values of 88.9 ± 0.8 for Tongo and 89.6 ± 1.2 for Weasua, as well as similar minor and trace element concentrations. Thus, whereas the Tongo and Weasua rock types are classified as kimberlite and olivine lamproite, respectively, the olivine chemistry suggests a similar petrogenetic evolution.
•Here we classify unusual transitional kimberlite-lamproites from West Africa.•Tongo rocks are micaceous transitional kimberlites.•Weasua rocks are diopside-bearing olivine lamproites.•West African diamondiferous rocks defy clear classification.•Olivine chemistry indicates similar petrogenesis both localities.
A network model for Ebola spreading Rizzo, Alessandro; Pedalino, Biagio; Porfiri, Maurizio
Journal of theoretical biology,
04/2016, Letnik:
394
Journal Article
Recenzirano
The availability of accurate models for the spreading of infectious diseases has opened a new era in management and containment of epidemics. Models are extensively used to plan for and execute ...vaccination campaigns, to evaluate the risk of international spreadings and the feasibility of travel bans, and to inform prophylaxis campaigns. Even when no specific therapeutical protocol is available, as for the Ebola Virus Disease (EVD), models of epidemic spreading can provide useful insight to steer interventions in the field and to forecast the trend of the epidemic. Here, we propose a novel mathematical model to describe EVD spreading based on activity driven networks (ADNs). Our approach overcomes the simplifying assumption of homogeneous mixing, which is central to most of the mathematically tractable models of EVD spreading. In our ADN-based model, each individual is not bound to contact every other, and its network of contacts varies in time as a function of an activity potential. Our model contemplates the possibility of non-ideal and time-varying intervention policies, which are critical to accurately describe EVD spreading in afflicted countries. The model is calibrated from field data of the 2014 April-to-December spreading in Liberia. We use the model as a predictive tool, to emulate the dynamics of EVD in Liberia and offer a one-year projection, until December 2015. Our predictions agree with the current vision expressed by professionals in the field, who consider EVD in Liberia at its final stage. The model is also used to perform a what-if analysis to assess the efficacy of timely intervention policies. In particular, we show that an earlier application of the same intervention policy would have greatly reduced the number of EVD cases, the duration of the outbreak, and the infrastructures needed for the implementation of the intervention.
•We define a realistic Ebola model that does not rely on homogeneous mixing.•We reproduce the dynamics of the 2014–2015 Ebola outbreak in Liberia.•We model non-ideal and time-varying intervention policies.•We assess the efficacy intervention policies with respect to their application time.
Get all three comprehensive reports bundled into one for a complete media and communications profile of Liberia. An excellent source of practical information, this profile offers an extensive dialing ...guide with city codes, a listing of ISPs and Internet cafes, profiles of the major media outlets (with contact info!) and more.
Background
Epidemics remain a major threat, impacting lives around the globe. We ask whether and to what extent individuals learn from past epidemics in Liberia, a country affected by both the ...2014-2016 Ebola Virus Disease and COVID-19.
Methods
We explored the association between being exposed to the 2014–2016 Ebola epidemic and measures of beliefs, intentions, and behavior during COVID-19. We interviewed 600 respondents three times over seven years, sampled by an initial list of 2,265 respondents in 571 villages across all of Liberia selected through Random Digit Dialing (RDD) in 2015-2016. We used an Ordinary Least Square (OLS) model, controlling for county fixed effects and a set of socio-demographic and economic covariates.
Results
Because of the selection among individuals with mobile phones, most respondents were male, educated, and were more likely to be from urban areas and wealthy. They were, on average, 33.9 (SD=10.4) years old, 66% were Catholic, and only 23% were unemployed. 22.8% of respondents reported that they knew someone in their community who got or was suspected of having Ebola; 13.7% were exposed to COVID-19, while 4.5% were exposed to both epidemics. We found that those exposed to Ebola were less likely to have wrong beliefs about the virus and how to cure it; they were also more likely to state that they would go to the health facility for important needs such as birth delivery and child routine vaccination; and, they were more likely to get vaccinated during COVID-19. The findings are primarily driven by individuals with low trust in the government.
Conclusions
This research suggests that individuals who experience a previous epidemic learned from it and might be more responsive to correct information and better respond to a future one. This has policy implications for patient education and awareness campaigns during the next epidemic.
To support Liberia's response to the ongoing Ebola virus (EBOV) disease epidemic in Western Africa, we established in-country advanced genomic capabilities to monitor EBOV evolution. Twenty-five EBOV ...genomes were sequenced at the Liberian Institute for Biomedical Research, which provided an in-depth view of EBOV diversity in Liberia during September 2014-February 2015. These sequences were consistent with a single virus introduction to Liberia; however, shared ancestry with isolates from Mali indicated at least 1 additional instance of movement into or out of Liberia. The pace of change is generally consistent with previous estimates of mutation rate. We observed 23 nonsynonymous mutations and 1 nonsense mutation. Six of these changes are within known binding sites for sequence-based EBOV medical countermeasures; however, the diagnostic and therapeutic impact of EBOV evolution within Liberia appears to be low.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, ODKLJ, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
In June 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases surged in Liberia. SARS-CoV-2 sequences from patients hospitalized during March–July 2021 revealed the Delta variant ...was in Liberia in early March and was dominant in June, irrespective of geography. Mutations and deletions suggest multiple SARS-CoV-2 Delta variant introductions.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, ODKLJ, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
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