Blues z rimskega zidu Auden, WH; Grošelj, Nada
Clotho (Ljubljana, Online),
08/2020, Letnik:
2, Številka:
1
Journal Article
Recenzirano
Odprti dostop
Nad barjem je veter in moker je zrak,
uši imam v tuniki, v nosu prehlad.
Z neba štropotajo nalivi dežja,
vojak sem na zidu, ne vem sploh, zakaj.
Po sivem kaménju se plazi megla,
dekle imam v ...Tungriji, jaz pa spim sam.
OBJECTIVE: To evaluate the acceptance of, adherence to, and outcomes of latent tuberculous infection (LTBI) treatment among health care workers (HCWs).DESIGN: This was a retrospective study in a ...tertiary hospital in Korea. From May to August 2017, 2190 HCWs simultaneously underwent
a tuberculin skin test (TST) and interferon-gamma release assay (IGRA). LTBI was diagnosed if the TST induration was 10 mm or IGRA results were positive.RESULTS: Of 2190 HCWs tested, 1006 (45.9%) were diagnosed with LTBI. Of these, 655 (65.1%) HCWs visited out-patient clinics, 234
(35.7%) of whom were advised treatment by physicians. Among these, 120 (51.3%) accepted the physicians' recommendations. In general, HCWs who were older, male and smoked were less likely to visit out-patient clinics. Sixty (50%) HCWs received 3 months of isoniazid plus rifampicin (3HR) and
57 (47.5%) HCWs received 4 months of rifampicin (4R). The proportion of HCWs with 2 side effects (3HR 20% vs. 4R 7.0%, P = 0.041) and drug stoppage rate (3HR 20% vs. 4R 5.3%, P = 0.017) were higher in the 3HR group than in the 4R group. Of the 120 HCWs, 78 (65%) completed
LTBI treatment.CONCLUSION: Overall, the acceptance and completion rate for LTBI treatment was not adequate. For effective LTBI management in HCWs, further programmatic strategies are needed.
Paleocene–Eocene phosphorite beds from three major outcrops of the Maknassy-Mezzouna basin (Central-Tunisia) were geochemically investigated to improve local stratigraphy, determine their ages, and ...attempt to constrain ocean circulation.
87
Sr/
86
Sr ratios of phosphate materials from the Chouabine Formation display a large variation even within the same deposit (
87
Sr/
86
Sr between 0.707782 and 0.707830). Based on the Sr isotope data obtained in teeth enamels, further supported by the results in coprolites, Sr isotope ages of 57 ± 1.1 Ma were attributed to Layers I and II, and 62 ± 1.4 Ma to Layer III. These results assign a Paleocene Epoch for the principal phosphate series. The
87
Sr/
86
Sr value of teeth enamel sample from the upper phosphate bed suggests an age of 46 ± 1 Ma for this sequence. Furthermore, the Nd isotopic compositions of these samples were used as a tracer for seawater circulation. The
143
Nd/
144
Nd values of the analyzed samples vary between 0.512174 and 0.512202, corresponding to εNd
CHUR
between – 8.1 and – 8.4. These values are similar to those reported from Gafsa-Metlaoui basin, southern Tunisia and other North African phosphorite deposits. These data are reminiscent of those of the Atlantic Ocean, which is new argument of the overturning of Tethys Circumglobal Current during the Paleogene period. The obtained results suggest water exchange between Tethys and Atlantic Ocean during this period.
Non-alcoholic Fatty Liver Disease (NAFLD) is one of the diseases that have evolved lately into a major challenge for gastroenterologists. Although, the term NAFLD has not been familiar to the medical ...world since long, other conditions resembling the presentation of NAFLD have been there since primitive times. It is a reversible condition of the liver, wherein large vacuoles of triglyceride fat accumulates in liver cells via the process of steatosis, despite any evidence of excessive alcohol consumption. In the developed countries NAFLD is reported to be the most common liver disorder, with a worldwide prevalence of 6–35%, in India its prevalence has been increasing gradually. Unani physicians have described liver as one of the principal organs of the body. It is the primary source of natural faculties, where the functions of digestion, concoction, absorption and excretion are performed, normally temperament of liver is hot and moist which can get converted to cold due to mutable dietary habits, consumption of fatty and cold food in abundance etc. In Unani System of Medicine, NAFLD has not been described as such, but it can be studied under
due to correlation of most of the symptoms. Its management mainly consists of elimination of morbid matter which is accumulated in the liver and correction of
by using drugs having opposite temperament (
).
U ovom radu opisan je utjecaj izgradnje obalnog zida na postojećoj prirodnoj stjenovitoj obali na dinamiku valovanja ispred obale, na primjeru projektiranja plaže Kostanj u Rijeci. Analize postojećeg ...i projektiranog stanja valovanja provedene su korištenjem numeričkog modela valovanja Simulating Waves Nearshore (SWAN) uz primjenu autorskih algoritama neophodnih za prikaz rezultata numeričkih simulacija. Predviđa se proširenje postojeće plaže prema zapadnom dijelu uvale nasipavanjem prirodne obale te izgradnjom armirano-betonskih zidova prema moru. Zbog izgradnje obalnih zidova doći će do povećanja koeficijenta refleksije valova u odnosu na postojeću stjenovitu obalu. Ispred projektiranog zida, značajne visine valova juga 50 godišnjeg povratnog perioda povećat će se sa 2,20 na 2,50 m. U radu su opisane konstrukcijske metode umanjenja nepovoljnog učinka izgradnje obalnog zida na postojećoj stjenovitoj obali. Kao primjer opisano je i simulirano djelovanje zaštitnog podmorskog praga na polje valovanja ispred obalnog zida. Izgradnjom zaštitnog podmorskog praga s dubinom uronjenosti krune -2,0 m n.m. simulirane značajne visine valova juga 50 godišnjeg povratnog perioda su 1,90 m ispred projektiranog obalnog zida.
This paper describes the impact of a sea wall on an existing rocky coastline wave dynamic, on the example of the Kostanj beach in Rijeka. Existing and designed significant waves heights were analysed by a numerical wave model Simulating Wave earshore (SWAN), with the application of the original algorithms for illustrating the numerical simulation results. The existing beach design proposes an extension of the existing beach on the western part of the bay by building coastal walls along thenatural coastline. This will increase the wave reflection coefficient relative to the existing coastline. In front of the designed wall a 50-year return period SSE significant wave height will increase from 2,20 to 2,50 m. This paper describes the construction methods for reducing the negative effect of construction of a coastal wall on an existing rocky shoreline. As described and simulated, the submerged breakwater with crown position at 2 m a.s.l. depth, reduces 50 years return period SSE significant wave height from 2,50 to 1,90 m.
We describe a novel zinc finger protein, ZID (zinc finger protein with interaction domain). At its amino terminus ZID contains a 120-amino-acid conserved motif present in a large family of proteins ...that includes both the otherwise unrelated zinc finger proteins, such as Ttk, GAGA, and ZF5, and a group of poxvirus proteins: We therefore refer to this domain as the POZ (poxvirus and zinc finger) domain. The POZ domains of ZID, Ttk, and GAGA act to inhibit the interaction of their associated finger regions with DNA. This inhibitory effect is not dependent on interactions with other proteins and does not appear dependent on specific interactions between the POZ domain and the finger region. The POZ domain acts as a specific protein-protein interaction domain: The POZ domains of ZID and Ttk can interact with themselves but not with each other, POZ domains from ZF5, or the viral protein SalF17R. However, the POZ domain of GAGA can interact efficiently with the POZ domain of Ttk. In transfection experiments, the ZID POZ domain inhibits DNA binding in NIH-3T3 cells and appears to localize the protein to discrete regions of the nucleus. We discuss the implications of multimerization for the function of POZ domain proteins.
Aerospace as a whole, primarily aviation and planes, for a short time after 1903, greatly advance the frontiers of human activity. Initially, unsafe "flying device" the plane, has become a factor in ...loose resolving wars and one of the reliable means of transport and communication between people around the world. Quick technical and technological development required a special approach. Mass production and use of aircraft, brought in light the need for standardization in the production, testing and lead into operational use of combat aircraft, as well as in commercial use for the purposes of air traffic. Testing the aircraft, is now more disciplinary research activity of a large number of experts from various fields, including test pilot who is an irreplaceable member. At that goal the test-measuring equipment (IMO), are specifically designed, and test pilots are trained in specialized schools for the experiment pilots. / Авиация в целом, а в частности развитие конструкций самолетов, в течение короткого времени, начиная с 1903 года, в значительной степени расширили границы человеческой деятельности. Первые «воздухоплавательные снаряды» трудно было назвать безопасными, но вскоре самолеты стали решающим фактором в войнах и одним из самых надежных средств передвижения и связи между людьми по всему миру. Быстрое техническое и технологическое развитие нуждалось в специальной методологии. Массовое производство и применение летательных аппаратов выявили необходимость в стандартизации в области производства, испытаний и их внедрения в военно-боевую эксплуатацию, а также в коммерческую эксплуатацию в целях воздушных перевозок. Таким образом, на сегодняшний день испытания самолетов включают мультидисциплинарные методы, в применении которых задействована большая команда специалистов и экспертов, представляющих различные области науки и техники, а главным участником данной команды неминуемо является летчик- испытатель. Для нужд испытательных мероприятий специально разрабатывается контрольно-измерительное оборудование, а сами летчики проходят специальное обучение в центре по подготовке летчиков-испытателей. / Vazduhoplovstvo u celini, a pre svega avijacija i avioni za kratko vreme, nakon 1903. godine, uveliko su pomerili granice ljudske delatnosti. Od 'klimavih' i nebezbednih letećih sprava, avion je postao rešavajući faktor u ratovima i jedno od pouzdanih sredstava prevoza i komunikacije među ljudima širom sveta. Brzi tehničko-tehnološki razvoj zahtevao je i poseban pristup. Masovna proizvodnja i korišćenje aviona iznedrili su potrebu za standardizacijom u proizvodnji, ispitivanju i uvođenje u operativnu upotrebu borbenih aviona, kao i uvođenje aviona za potrebe vazdušnog saobraćaja. Ispitivanje aviona danas je više diciplinarna istraživačka aktivnost velikog broja stručnjaka iz različitih oblasti, među kojima je opitni pilot nezaobilazni član. Radi toga se ispitno-merna oprema (IMO) posebno dizajnira, a opitni piloti obučavaju u specijalizovanim školama za opitne pilote.
In the last 15 years a role has been ascribed for the medullary dorsal reticular nucleus as a supraspinal pain modulating area. The medullary dorsal reticular nucleus is reciprocally connected with ...the spinal dorsal horn, is populated mainly by nociceptive neurons and regulates spinal nociceptive processing. Here we analyze the distribution of brain projections from the medullary dorsal reticular nucleus using the iontophoretic administration of the anterograde tracer biotinylated-dextran amine and the retrograde tracer cholera toxin subunit B.
Fibers and terminal boutons labeled from the medullary dorsal reticular nucleus were located predominately in the brainstem, although extending also to the forebrain. In the medulla oblongata, anterograde labeling was observed in the orofacial motor nuclei, inferior olive, caudal ventrolateral medulla, rostral ventromedial medulla, nucleus tractus solitarius and most of the reticular formation. Labeling at the pons-cerebellum level was present in the locus coeruleus, A5 and A7 noradrenergic cell groups, parabrachial and deep cerebellar nuclei, whereas in the mesencephalon it was located in the periaqueductal gray matter, deep mesencephalic, oculomotor and anterior pretectal nuclei, and substantia nigra. In the diencephalon, fibers and terminal boutons were found mainly in the parafascicular, ventromedial, and posterior thalamic nuclei and in the arcuate, lateral, posterior, peri- and paraventricular hypothalamic areas. Telencephalic labeling was consistent but less intense and concentrated in the septal nuclei, globus pallidus and amygdala.
The well-known role of the medullary dorsal reticular nucleus in nociception and its pattern of brain projections in rats suggests that the nucleus is possibly implicated in the modulation of: (i) the ascending nociceptive transmission involved in the motivational-affective dimension of pain; (ii) the endogenous supraspinal pain control system centered in the periaqueductal gray matter–rostral ventromedial medulla–spinal cord circuitry; (iii) the motor reactions associated with pain.
Zagreb je tijekom 2020. pogodio niz potresa koji su uzrokovali znatna oštećenja na zagrebačkim gornjogradskim i donjogradskim blokovima. Najznačajnija oštećenja nastala su na nekonstrukcijskim ...elementima te ovaj rad obrađuje načine sanacije tavanskih i zabatnih zidova. Prilikom projektiranja građevina početkom 20. stoljeća nije se poznavalo djelovanje potresa u dovoljnoj mjeri, te se nisu primjenjivali adekvatni konstruktivni sistemi za gradnju u seizmičkim aktivnim područjima. U radu je prikazana sanacija tavanskog zida na objektu Pierottijeva 11 i zabatnog zida objekta Nazorova 2, koji predstavljaju karakteristične primjere gradnje toga vremena. Navedeni primjeri daju projektantima pregled potencijalnih problema s kojima se mogu susresti prilikom izrade projektne dokumentacije, uz predložena rješenja i prikaz karakterističnih detalja primijenjenih tijekom sanacije.
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