The quality and safety of the alimentary products have become a right of the consumers, with direct effects on the quality of life, and the problems based on the quality and the safety of the ...products is in the center of attention for organisms set up for defending the consumers interests. The milk goat tests were performed using LactoStar and ColonyStar on an effective of 90 goats in three different areas of the county of Sibiu: Răşinari, Cristian, Miercurea Sibiului. Each batch is composed of 30 goats. The test results should prevent the farmer and make him to be more attentive in milk hygiene.
Solid oxide electrolysis cells (SOECs) have garnered interest as efficient devices for production of clean fuel such as hydrogen gas. However, the industrialization of SOEC technology has encountered ...significant challenges, such as unsatisfactory performance and insufficient durability. In this study, we aimed to improve the electrochemical performance and stability of the SOEC air electrode by modifying it at various annealing temperatures (900, 1000, and 1100 °C). Electrochemical testing revealed that the SOEC cell with the electrode annealed at 1000 °C for 1 h exhibited the highest current density of 0.88 A/cm2 at 750 °C and 1.3 V, which is 1.76-times higher than that of the cell with the unoptimized electrode annealed at 900 °C. Three-dimensional microstructural analyses using Focused Ion Beam-Scanning Electron Microscope (FIB-SEM) confirmed that the optimized cell is the most porous with sufficient pore surface area, thereby facilitating electrochemical reactions and gas transport, and preventing delamination of the air electrode resulting from lower oxygen partial pressure difference between the barrier layer and air/electrode interface. Side reactions at the interface, including the generation of resistant SrZrO3, are concurrently avoided. These findings demonstrate the potential of the modified SOEC air electrode for improving electrochemical performance and stability.
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•Explored the optimum annealing temperature of LSCF-GDC oxygen electrode of SOEC.•The structure of the oxygen electrode was analyzed using FIB-SEM.•The average size of LSCF-GDC particles increases with the annealing temperature.•The optimized performance of large-area SOEC reaches 0.88 A/cm2.
Triclosan (TCS) is a broad-spectrum antibiotic widely used in various personal care products. Research has found that exposure to TCS can cause toxic effects on organisms including neurotoxicity, ...cardiotoxicity, disorders of lipid metabolism, and abnormal vascular development, and the corresponding toxic mechanisms are gradually delving into the level of abnormal expression of miRNA regulating gene expression. Although the downstream mechanism of TCS targeting miRNA abnormal expression to induce toxicity is gradually improving, its upstream mechanism is still in a fog. Starting from the abnormal expression data of circRNA in zebrafish larvae induced by TCS, this study conducted a hierarchical analysis of the expression levels of all circRNAs, differential circRNAs, and trend circRNAs, and identified 29 key circRNA events regulating miRNA abnormal expression. In combination with GO and KEGG, the effects of TCS exposure were analyzed from the function and signaling pathway of the corresponding circRNA host gene. Furthermore, based on existing literature evidence about the biological toxicity induced by TCS targeting miRNA as data support, a competing endogenous RNAs (ceRNA) network characterizing the regulatory relationship between circRNA and miRNA was constructed and optimized. Finally, a comprehensive Adverse Outcome Pathway (AOP) framework of multiple levels of events including circRNA, miRNA, mRNA, pathway, and toxicity endpoints was established to systematically elucidate the toxic mechanism of TCS. Moreover, the rationality of the AOP framework was verified from the expression level of miRNA and adverse outcomes such as neurotoxicity, cardiotoxicity, oxidative stress, and inflammatory response by knockdown of circRNA48. This paper not only provides the key circRNA events for exploring the upstream mechanism of miRNA regulating gene expression but also provides an AOP framework for comprehensively demonstrating the toxicity mechanism of TCS on zebrafish, which is a theoretical basis for subsequent hazard assessment and prevention and control of TCS.
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•All circRNAs of zebrafish exposed to gradient concentration triclosan were detected.•29 key circRNA events bound miRNA were identified in zebrafish exposed to triclosan.•A ceRNA network was constructed and optimized based on existing literature evidence.•A comprehensive AOP framework including multiple toxicity endpoints was constructed.•The rationality of the AOP framework was verified by knocking down typical circRNA48.
The aim of this research is to know suitability of fourth grade students’ book based on 2013 Curriculum theme Pahlawanku Subtheme Pahlawanku Kebanggaanku on lesson five with core competencies, ...learning objectives, indicators, materials, tool and learning resources. This section is eleventh fragment of eighteen fragment of analysis of fourth grade students’ book on theme Pahlawanku. This research using qualitative descriptive method. Which analyze students’ book on fourth grade.then discussing the suitability according with the rule of Ministry of Education and Culture and the implementation of Curriculum 2013. The result showed that 1) lesson five corresponding with core competencies; 2) there is indicator on lesson five to narrow for PPKN subject; 3) lesson five corresponding with learning objectives; 4) there is learning activity not corresponding on lesson five; 5) there is some materials to narrow on lesson five; and 6) lesson five corresponding with tools and learning resources.
Climate change and urbanization are converging to challenge the flood control in the Pearl River Delta (PRD) due to their adverse impacts on precipitation extremes and the urban areas environment. ...Previous studies have investigated temporal changes in flood risk with various single factor, few have considered the joint effects of climate change, urbanization and socio-economic development. Here, based on the representative concentration pathway (RCP) scenarios, we conducted a comprehensive assessment of future (2030–2050) flood risk over the PRD combined with a thorough investigation of climate change, urbanization and socio-economic development. Precipitation extremes were projected using the regional climate model RegCM4.6, and urbanization growth was projected based on the CA-Markov model. The economic and population development was estimated by the shared socio-economic pathways (SSPs). Flood risk mapping with different RCPs-urbanization-SSPs scenarios was developed for the PRD based on the set pair analyze theory. The results show that climate change and urbanization are expected to exacerbate flood risk in most parts of the PRD during the next few decades, concurrently with more intense extreme precipitation events. The high flood risk areas are projected mainly in the urban regions with unfavorable terrain and dense population. The highest flood risk areas are expected to increase by 8.72% and 19.80% under RCP4.5 and RCP8.5 scenarios, respectively. Reducing greenhouse gas emissions may effectively mitigate the flood risk over the PRD. This study highlight the links between flood risk and changing environment, suggesting that flood risk management and preventative actions should be included in regional adaptation strategies.
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•Predict future extreme precipitation changes using the RegCM4.6 downscaling outputs•Apply CA-Markov model to simulate and predict spatially explicit land use change•Joint the effects of climate change, urbanization, and socio-economic on flood risk•Unfavorable terrain and densely populated urban areas are at greatest risk•Reduce greenhouse gas emissions may effectively mitigate flood risk over the PRD
This paper aims to identify sectorial interdependencies in terms of pollution, in terms of cost and environmental investments and the development of a mathematical model in which all links to be ...established and statistically expected. In order to achieve this, one must allow for the maximum exploitation of the region’s potential in consonance with the processes related to environmental protection, to eradicating (attenuating or diminishing) and tracking those elements that prevent or delay the growth process, to tracking those external factors (national or international) that can contribute to the development of a region.
Background and Objectives: Hemovigilance is a prime requirement for safe transfusion practice rather it may be the reflection of laboratory performance in a blood bank. This study is the first report ...of transfusion errors and adverse reactions recorded in Bangladesh. It is a new approach to collect and analyze the data pertaining to issues associated with blood transfusion in the day care. This study is aimed to perceive the frequency of adverse reactions and the errors associated with its barrier. Methods: This cross-sectional observational study was conducted in the daycare unit of the Department of Transfusion Medicine of Bangabandhu Sheikh Mujib Medical University from July 2018 to June 2019. Any error regarding pretransfusion and transfusion procedure and adverse event following transfusion was noted according to departmental standard operating procedure and collected data were analyzed with Microsoft Excel 2016. Results: Of the 10,762 units of blood component selected for the issue to 6995 patients, 66 units were discarded. For various reasons. Out of 10696 units of blood component transfused, a total of 459 (4.29%) transfusion reactions were observed among which 390 (3.6%) were acute and 69 (0.6%) were delayed. Mild allergic (40.5%) and Febrile nonhemolytic (36.4%) were the most common acute reaction whereas alloimmunization (9.4%) and delayed hemolysis (4.1%) were the most observed delayed transfusion reaction. Among the recipient, transfusion reactions were observed slightly more in males (7.5%) than in females (5%) and the most affected age group was 20-29 years. Conclusion: However, it is not always possible to analyze the relevance of all the transfusions and the outcome of the patient. Now, a developing country like Bangladesh has to face and notify the errors and to solve them in parallel.
Objective To construct and compare the methods for correlation analysis of different elements in rice, including barium, vanadium, cadmium, lithium, aluminum, manganese, lead, thallium, antimony, ...copper, selenium, ehromium, mercury and arsenic. Methods Analyze the correlation among the fourteen elements in rice by two methods: Pearson correlation coefficient and partial correlation coefficient, and compare the two methods. Results Both of the methods can find the correlations among various pollutants from the data and have their own characteristics on computational complexity, information abundancy and other aspects: Pearson correlation coefficient method has less computation, but also provides less information; Partial correlation coefficient provides more information but needs more samples and computing resources. The Pearson correlation coefficient method showed the positive correlation elements including barium-vanadium, barium-lead, vanadium-lithium, aluminum-antimony and copper-thallium. There was no si
Creating common added value for organizations and society is a modern topic of discussion in the circles of practitioners and representatives of local communities. Organizational social ...responsibility, as a tool that achieves this connection, has been the subject of specialized studies since the beginning of the 20th century. The objective of the article is to identify and quantitatively analyze the publications that dealt with the “intersection” between the terms “joint added value” and “organizational social responsibility”, capitalizing on the way in which they influence each other, with the effect of amplifying the results. The method used is the bibliometric analysis, and the results highlight a relatively recent interest in studies aimed at this objective, with an intensification of the scientific effort after 2016. The newest works have addressed the creation of added value as a condition for ensuring organizational sustainability or as a starting point in achieving organizational alignment with sustainable development objectives.