To clarify variations of diagnosis and treatment in the emergency care of critically ill patients not infected with novel coronavirus (COVID-19) prior to and amidst the COVID-19 pandemic.
A ...retrospective cohort study was conducted to compare and analyze the diagnosis and treatment data of critically ill patients with non-COVID-19 infection who were admitted to the emergency department of the Fourth Medical Center of Chinese PLA General Hospital from January 2019 to November 2022. The variations in emergency care of the pandemic were summarized, and the influence of the pandemic on emergency care was assessed.
A total of 6634 critically ill patients with non-COVID-19 infection were included in this study. These patients were elderly, high incidence of chronic diseases, and extended emergency duration during the pandemic. Notably, the proportion of patients requiring intensive care was twofold higher compared to the period before the pandemic. Throughout the pandemic, patients experienced prolonged emergency durations, increased overall costs and daily expenses per patient. Further investigation revealed that elderly patients exhibited worse medical conditions, requiring lengthier emergency treatment and incurring escalated healthcare expenses. However, the presence of pre-existing chronic diseases did not appear to influence disease severity, nor extended emergency durations or heightened healthcare expenditures. Irrespective of the pandemic phase-be it short-term, medium-term, or long-term emergency care-greater healthcare spending was necessary.
There was no difference in the disease spectrum of emergency critical ill patients with non-COVID-19 infection prior to and amidst the COVID-19 pandemic, nor the duration and expenditure in prior chronic illness patients. However, the disease severity and emergency duration have led to an increase in the total cost and economic intensity of emergency care for all patients during the epidemic. Especially, elderly patients required longer emergency duration, greater healthcare spending, and more inpatient medical resources than usual.
Coronaviruses have caused multiple global pandemics. As an emerging epidemic, the coronavirus disease relies on nonpharmacological interventions to control its spread. However, the specific effects ...of these interventions are unknown. To evaluate their effects, we extend the susceptible–latent–infectious–recovered model to include suspected cases, confirmed cases, and their contacts and to embed isolation, close contact tracing, and quarantine into transmission dynamics. The model simplifies the population into two parts: the undiscovered part (where the virus spreads freely—the extent of freedom is determined by the strength of social distancing policy) and the discovered part (where the cases are incompletely isolated or quarantined). Through the isolation of the index case (suspected or confirmed case) and the subsequent tracing and quarantine of its close contacts, the infections flow from the undiscovered part to the discovered part. In our case study, multisource data of the novel coronavirus SARS-CoV-2 (COVID-19) in Wuhan were collected to validate the model, the parameters were calibrated based on the prediction of the actual number of infections, and then the time-varying effective reproduction number was obtained to measure the transmissibility of COVID-19 in Wuhan, revealing the timeliness and lag effect of the nonpharmacological interventions adopted there. Finally, we simulated the situation in the absence of a strict social distancing policy. Results show that the current efforts of isolation, close contact tracing, and quarantine can take the epidemic curve to the turning point, but the epidemic could be far from over; there were still 4,035 infected people, and 1,584 latent people in the undiscovered part on March 11, 2020, when the epidemic was actually over with a strict social distancing policy.
In this paper, we have mapped the coping methods used to address the coronavirus pandemic by members of the academic community. We conducted an anonymous survey of a convenient sample of 674 ...faculty/staff members and students from September to December 2020. A modified version of the RCOPE scale was used for data collection. The results indicate that both religious and existential coping methods were used by respondents. The study also indicates that even though 71% of informants believed in God or another religious figure, 61% reported that they had tried to gain control of the situation directly without the help of God or another religious figure. The ranking of the coping strategies used indicates that the first five methods used by informants were all non-religious coping methods (i.e., secular existential coping methods): regarding life as a part of a greater whole, regarding nature as an important resource, listening to the sound of surrounding nature, being alone and contemplating, and walking/engaging in any activities outdoors giving a spiritual feeling. Our results contribute to the new area of research on academic community's coping with pandemic-related stress and challenges.
The sudden appearance of a new epidemic disease in China created the need for names identifying that disease. Between December 2019 and January 2020, a variety of severe pneumonia-related disease ...names suddenly appeared, and more name varieties kept coming up afterwards. To better understand the introduction and spread of these names, 16 different COVID-19-related name varieties were selected covering the period from the end of December 2019, when the epidemic started, to mid-March 2020, a moment at which the term competition had stabilized. By way of big data analysis, the initiation and distribution of the 16 names across the media landscape was traced with regard to the impact of different media platforms, while the distribution frequency of each of the selected terms was mapped, resulting in a distinction of three groups of disease names, each with a different media and time profile. The results were discussed based on the hypotheses of disease confusion by name variety and management failures in absence of clear language governance at the national and global levels. The analysis of the data led to a refutation of both hypotheses. Based on this discussion, the study offers empirically based suggestions for the WHO in their naming practices and further research.
The aim is to study the dynamics of Coronavirus model using stochastic methods. Threshold parameter
R
0
is obtained for the model. Afterwards, both the disease-free equilibrium (DFE) and endemic ...equilibrium (EE) points are acquired and the stability of the model is discussed. Both the equilibrium points are locally asymptotically stable. Euler–Maruyama, stochastic Euler scheme (SES), stochastic fourth-order Runge–Kutta scheme (SRKS) and stochastic non-standard finite difference technique (SNFDT) are applied to solve the model equations. Euler–Maruyama, SES, SRKS fail for large time step size, while, SNFDT preserves the dynamics of the proposed model for any step size. Numerical comparison of applied methods is provided using different step sizes.
Coronavirus Disease 2019 (COVID-19) results from Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). it is now a pandemic that affects us all. For patients referring to the addiction care ...systems, this pandemic can create additional vulnerabilities. A great deal of effort has made to re-organize the care systems for patients with addiction. Our study focuses on the voice of our patients, on clues to adapt treatment, and on the impact of the pandemic on the therapeutic alliance.
A qualitative design was used to develop a description and understanding of general and clinically relevant aspects of the impact of the COVID-19 pandemic. Fifteen addicted patients (11 under treatment and 4 in recovery) were interviewed by 4 interviewers according to the COREQ (consolidated criteria for reporting qualitative research).
COVID-19 has had a serious impact on thoughts, feelings, and behaviors. Interviewees shared their anxieties about their health and the health of their relatives. Frightening thoughts were associated with a range of negative feelings and behaviors, such as stress, anger, avoidance, and isolation. The use of psychoactive substances differed between the patients in treatment with those who are in stable recovery. In the former, all succeeded in staying abstinent. They have experienced that solidarity and connectedness were essential in sustaining their recovery. Those still in treatment were fighting against the temptation to start using again; they felt emotionally isolated and sometimes patronized by health care workers.
The elaboration of the interviewees on the therapeutic relationship provides promising clues to optimize that relationship. Remembering this common expression, "we are all in this together", shared decision making could very well be used to shape effective and receptive treatment interventions during the different challenges faced at different stages of the COVID-19 epidemic.
This paper concerns the legal instruments and principles used in Czech social security law in order to protect social rights endangered because of the coronavirus epidemic. It is focused on the forms ...of assistance in case of social events such as temporary incapacity to work, quarantine or closure of educational institutions. One specific chapter deals with some supportive measures targeted at employers.
Under the current epidemic of the coronavirus disease of 2019 (COVID-19), there is a need to distinguish the differences between the laboratory examinations of COVID-19-infected patients, tumor ...patients with fever, and those with normal fever patients. We aimed to investigate the temperature of tumor patients with different tumor burdens, stages, and cancer types.
We recruited 3 groups of patients to this study: fever patients with malignant tumors, ordinary fever patients, and confirmed cases of COVID-19, with 31, 55, and 28 cases in each group, respectively.
The levels of leukocytes and neutrophils were the highest among non-tumor patients, and the count of COVID-19 was the lowest, with a P value of 0.000. Among the leukocytosis group, non-tumor patients had the highest proportion (43.6%), while that of COVID-19 was only 3.6% (P=0.000). Similarly, there were significant differences in the grading of neutrophils, where most of the infected patients were in the normal group and the P value was 0.000. The lymphocyte count of the tumor group was significantly reduced, with an average of (0.97±0.66) ×109/L (P=0.004). In the lymphocyte grades, most of the infected patients were the normal group (71.4%), while tumor patients in the lymphocytopenia group accounted for 63.1% (P=0.006). There were also significant differences in the neutrophil to lymphocyte ratio (NLR) (P=0.006). There was a significant difference in temperature between different tumor burden groups (P=0.014).
The normal fever group had the highest count of leukocyte and neutrophils, whereas the infected group had the lowest relative count. The NLR was the lowest in the infected group. The NLR was higher in the bigger tumor load group.
This paper concerns the legal instruments and principles used in Czech social security law in order to protect social rights endangered because of the coronavirus epidemic. It is focused on the forms ...of assistance in case of social events such as temporary incapacity to work, quarantine or closure of educational institutions. One specific chapter deals with some supportive measures targeted at employers.
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