This work presents the development of two free graphical user interfaces (GUIs), called FASTLognoter and MorisonForm, both focused on the analysis of the behaviour of offshore structures, especially ...of offshore wind turbines. The first one is related to the aeroelastic analysis of wind turbines, and the second is concerned with the seakeeping of marine structures. The development of these tools has been carried out using a powerful software called Lognoter. This tool is a free software for knowledge management in technology, which integrates computer programming for allowing the development of GUIs. These GUIs give an open platform for conducting a parametric study of the structural and dynamic behaviour of marine structures. Their coupling permits the user to set a suitable way to evaluate new concepts in marine structures. Finally, an application for the intensive analysis of offshore wind turbines is shown.
SECav. Educational software for numerical calculus Ascheri, M. E.; Pizarro, R. A.; Astudillo, G. J. ...
2017 Twelfth Latin American Conference on Learning Technologies (LACLO),
2017-Oct.
Conference Proceeding
This article describes SECav, an educational software developed in the context of a research project, with the aim of supporting the teaching and learning processes of a Numerical Calculus course ...that is taught for several courses of the Exact and Natural Sciences Faculty of the UNLPam University. SECav focuses on the numerical resolution of nonlinear equations, polynomial interpolation and approximation, and adjustment of least squares, numerical integration and ordinary differential equations. The application was developed entirely with free tools.
Skillbox: Content Kelsey, Todd
Introduction to Social Media Marketing,
06/2017
Book Chapter
This chapter takes a look at content related to social media, including tools you can use to “do it yourself”. You can think of it as a toolbox of skills, or a skillbox. You’ll take a tour of some of ...the things you should try when working with social media.
Nanotechnology applied to cancer treatment is a growing area of research in nanomedicine with magnetic nanoparticle-mediated anti-cancer drug delivery systems offering least possible side effects. To ...that end, both structural and chemical properties of commercial cobalt metal nanoparticles were studied using label-free confocal Raman spectroscopy.
Crystal structure and morphology of cobalt nanoparticles were studied by XRD and TEM. Magnetic properties were studied with SQUID and PPMS. Confocal Raman microscopy has high spatial resolution and compositional sensitivity. It, therefore, serves as a label-free tool to trace nanoparticles within cells and investigate the interaction between coating-free cobalt metal nanoparticles and cancer cells. The toxicity of cobalt nanoparticles against human cells was assessed by MTT assay.
Superparamagnetic Co metal nanoparticle uptake by MCF7 and HCT116 cancer cells and DPSC mesenchymal stem cells was investigated by confocal Raman microscopy. The Raman nanoparticle signature also allowed accurate detection of the nanoparticle within the cell without labelling. A rapid uptake of the cobalt nanoparticles followed by rapid apoptosis was observed. Their low cytotoxicity, assessed by means of MTT assay against human embryonic kidney (HEK) cells, makes them promising candidates for the development of targeted therapies. Moreover, under a laser irradiation of 20mW with a wavelength of 532nm, it is possible to bring about local heating leading to combustion of the cobalt metal nanoparticles within cells, whereupon opening new routes for cancer phototherapy.
Label-free confocal Raman spectroscopy enables accurately localizing the Co metal nanoparticles in cellular environments. The interaction between the surfactant-free cobalt metal nanoparticles and cancer cells was investigated. The facile endocytosis in cancer cells shows that these nanoparticles have potential in engendering their apoptosis. This preliminary study demonstrates the feasibility and relevance of cobalt nanomaterials for applications in nanomedicine such as phototherapy, hyperthermia or stem cell delivery.
This paper presents a gouge-free tool path generation method for direct ball-end cutter CNC milling of cloud of point. In this method, a base surface with simple geometry, which can approximately ...reflect the features and the changes of surface shape, is first constructed, and the guide curves with different patterns of the cutter motion are then planned on it. After the cloud of point is offset by a distance of the ball-end cutter radius, the guide curves are deformed onto the offset of cloud of point by point projection operation along the computed direction instead of the traditional z-axis direction, thereby forming the desired tool paths directly on the cloud of point. In projecting guide curves, the computation of the projecting direction and construction of the weight function are discussed in detail to eliminate the projection error as much as possible. The technique of adjusting the path points is also presented to eliminate the unfavorable undercuts and overcuts. Since the cloud of point is offset a distance of the cutter radius, the gouge between the cutter and the point set surface can be automatically avoided. Also, various patterns of the cutter motion can be conveniently planned on the simple base surface, such that the cloud of point can be milled along the generated tool paths with the most suitable topology. Finally, several examples are given to validate the proposed method.
We propose a method which uses interference-free tool paths to predict and compensate for deformation error during the spiral milling of blades. Firstly, a finite element simulation of the blisk ...blade milling process was conducted using an interference-free spiral milling NC machining tool path based on the curvature attribute of the blade twisted surface, observing the variation in blade milling error under different processing parameters and yielding a surface quality variation law. Next, the model was corrected by combining this error prediction data with precision design requirements, and a blade deformation error compensation scheme was suggested. Finally, an interference-free processing program containing the error compensation information was applied to carry out another blade milling simulation and a blisk milling experiment. The results showed that both the blade deformation error and the surface quality satisfied design requirements, while the accuracy of the simulation was verified.
A keyhole produced by friction stir weld bead on plate (4·7 mm thick 1060 Al plate) technique was filled using a method like rotational extrusion process, in which a pin free tool and a T shaped ...filler bit was used. As compared with the case using a simple cylindrical filler bit, in which all of the filled samples fractured at the initial periphery interface, the beneficial effect of T cap on improving filling quality was demonstrated by higher and more stable fracture load and fracture location away from initial periphery interface, although small gaps were present at the lower periphery interface and the bottom interface. To further eliminate the small gaps mentioned above with liquid phase, Zn braze foil was preplaced at the bottom of the keyhole. As expected, with the aid of the extruding and torquing effects of the pin free tool, intimate contact was achieved well by filling and alloying effects of molten Zn.
Celotno besedilo
Dostopno za:
DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, UILJ, UKNU, UL, UM, UPUK
Strategies for cutter size optimisation and interference-free tool path generation are proposed for five-axis flank milling of centrifugal impellers. To increase the material removal rate and provide ...a stronger tool shank during flank milling, the cutter size is first maximised under a set of geometric constraints. The tool path is then globally optimised in accordance with the minimum zone criterion for the determined optimal cutter size. Aside from the local interference of the cutter with the design surface, the global interferences with the hub surface and the adjacent blade surface are also considered in the optimisation models. Interference is indicated by the signed distance from the sampled point on the blade surface to the tool envelope surface. This distance is calculated without constructing the envelope surface. On the basis of the differential property of the distance function, we choose a sequential linear programming method in implementing the optimisations. This approach applies to generic rotary cutters, such as cylindrical and conical tools. Simulations are conducted to obtain the optimal cutter size and generate an interference-free tool path for a practical impeller. Simultaneously, a software module that can generate tool envelope surfaces and verify geometric errors is used to validate the proposed method.
PDF
