Heat shock protein 90 (Hsp90) is an ATP-dependent molecular chaperone which is essential in eukaryotes. It is required for the activation and stabilization of a wide variety of client proteins and ...many of them are involved in important cellular pathways. Since Hsp90 affects numerous physiological processes such as signal transduction, intracellular transport, and protein degradation, it became an interesting target for cancer therapy. Structurally, Hsp90 is a flexible dimeric protein composed of three different domains which adopt structurally distinct conformations. ATP binding triggers directionality in these conformational changes and leads to a more compact state. To achieve its function, Hsp90 works together with a large group of cofactors, termed co-chaperones. Co-chaperones form defined binary or ternary complexes with Hsp90, which facilitate the maturation of client proteins. In addition, posttranslational modifications of Hsp90, such as phosphorylation and acetylation, provide another level of regulation. They influence the conformational cycle, co-chaperone interaction, and inter-domain communications. In this review, we discuss the recent progress made in understanding the Hsp90 machinery.
This book investigates the discursive and performative strategies employed by Australian Indigenous rappers to make sense of the world and establish a position of authority over their identity and ...place in society. Focusing on the aesthetics, the language, and the performativity of Hip Hop, this book pays attention to the life stance, the philosophy, and the spiritual beliefs of Australian Indigenous Hip Hop artists as ‘glocal’ producers and consumers. With Hip Hop as its main point of analysis, the author investigates, interrogates, and challenges categories and preconceived ideas about the critical notions of authenticity, ‘Indigenous’ and dominant values, spiritual practices, and political activism. Maintaining the emphasis on the importance of adopting decolonizing research strategies, the author utilises qualitative and ethnographic methods of data collection, such as semi-structured interviews, informal conversations, participant observation, and fieldwork notes. Collaborators and participants shed light on some of the dynamics underlying their musical decisions and their view within discussions on representations of ‘Indigenous identity and politics’. Looking at the Indigenous rappers’ local and global aspirations, this study shows that, by counteracting hegemonic narratives through their unique stories, Indigenous rappers have utilised Hip Hop as an expressive means to empower themselves and their audiences, entertain, and revive their Elders’ culture in ways that are contextual to the society they live in.
Introduction: Culture on the Stage of History: The Past Is Present in ‘Indigenous Hip Hop’
Chapter 1: "The Black from Down-Unda": Contact Zones and Cultures of Black Resistance
Chapter 2: "2 Black 2 Strong": The Politics of Blackness and Identification
Chapter 3: ‘Indigenous Hip Hop’: The Politics of Identity and Representation
Chapter 4: "Know Our True Identity": Indigenous Articulations of Identity through Kin, Place, and Spirituality
Chapter 5: Hip Hop and Australian Indigenous Youth: New Modes of Political Participation
Conclusion: ‘Indigenous Hip Hop’: History in the making
"Hip Hop outside of the U.S. North American context has been largely mute for far too long. Yet, Hip Hop remains a powerful force throughout the globe. What Minestrelli has provided here is a window into the strong and current culture of Hip Hop within Australian contexts. This study examines the related history of Hip Hop within an indigenous context and provides the reader with an area of Hip Hop that is developing and connected to rich roots. Minestrelli’s work stands to be a cornerstone text in the field of Hip Hop Studies." — Daniel White Hodge, North Park University, USA
Chiara Minestrelli holds a PhD in Australian Indigenous studies from Monash University (2015). She is visiting professor in the Africana Studies Program at Lehigh University. She has published on Australian Indigenous literature and Hip Hop and Australian Indigenous Hip Hop.
Hip Hop Africa Charry, Eric; Polak, Rainer; Shipley, Jesse Weaver ...
10/2012
eBook
Hip Hop Africa explores a new generation of Africans who are not only consumers of global musical currents, but also active and creative participants. Eric Charry and an international group of ...contributors look carefully at youth culture and the explosion of hip hop in Africa, the embrace of other contemporary genres, including reggae, ragga, and gospel music, and the continued vitality of drumming. Covering Senegal, Mali, Côte d'Ivoire, Ghana, Nigeria, Kenya, Tanzania, Malawi, and South Africa, this volume offers unique perspectives on the presence and development of hip hop and other music in Africa and their place in global music culture.
Detroit, MIchigan, has long been recognized as a center of musical innovation and social change. Rebekah Farrugia and Kellie D. Hay draw on seven years of fieldwork to illuminate the important role ...that women have played in mobilizing a grassroots response to political and social pressures at the heart of Detroit's ongoing renewal and development project. Focusing on the Foundation, a women-centered hip hop collective, Women Rapping Revolution argues that the hip hop underground is a crucial site where Black women shape subjectivity and claim self-care as a principle of community organizing. Through interviews and sustained critical engagement with artists and activists, this study also articulates the substantial role of cultural production in social, racial, and economic justice efforts.
This vibrant book pulses with the beats of a new American South,
probing the ways music, literature, and film have remixed southern
identities for a post-civil rights generation. For scholar and
...critic Regina N. Bradley, Outkast's work is the touchstone, a blend
of funk, gospel, and hip-hop developed in conjunction with the work
of other culture creators-including T.I., Kiese Laymon, and Jesmyn
Ward. This work, Bradley argues, helps define new cultural
possibilities for black southerners who came of age in the 1980s
and 1990s and have used hip-hop culture to buffer themselves from
the historical narratives and expectations of the civil rights era.
Andre 3000, Big Boi, and a wider community of creators emerge as
founding theoreticians of the hip-hop South, framing a larger
question of how the region fits into not only hip-hop culture but
also contemporary American society as a whole. Chronicling
Stankonia reflects the ways that culture, race, and
southernness intersect in the late twentieth and early twenty-first
centuries. Although part of southern hip-hop culture remains
attached to the past, Bradley demonstrates how younger southerners
use the music to embrace the possibility of multiple Souths,
multiple narratives, and multiple points of entry to contemporary
southern black identity.
Featuring contributions from internationally recognized Hip Hop dancers, advocates, and scholars of various Hip Hop or streetdance practices, The Oxford Handbook of Hip Hop Dance Studies is the first ...collection devoted exclusively to the dances that fall under the rubric of Hip Hop. Each of its five sections explores different key themes relevant to streetdance: legacies and traditions, Hip Hop methodologies, the politics of identity, institutionalization, Hip Hop (dance) theatre, and issues of health, injury, and rehabilitation. This compendium of topics, approaches, theoretical influences, histories, and perspectives demonstrates the futures of a field in formation. It adds new resources to research in dance and Hip Hop studies, contributing to ongoing debates within Hip Hop dance communities globally.
Anthony Pinn examines how hip hop artists challenge white supremacist definitions of Blackness by challenging white distinctions between life and death.
Making Beats Schloss, Joseph G
2013, 2004, c2014., 2014-11-20
eBook
<!CDATADespite having created one of the most important musical cultures of the last fifty years, hip-hop composers who use digital sampling are rarely taken seriously as artists. But hip-hop deejays ...and producers have collectively developed an artistic system that features a complex aesthetic, a detailed array of social protocols, a rigorous set of ethical expectations and a rich historical consciousness.
Based on ten years of research among hip-hop producers, Making Beats is the first work of scholarship to explore the goals, methods and values of this surprisingly insular community. Focusing on a variety of subjects--from hip-hop artists' pedagogical methods to the Afro-diasporic roots of the sampling process to the social significance of digging for rare records--Joseph G. Schloss examines the way hip-hop artists have managed to create a form of expression that reflects their creative aspirations, moral beliefs, political values and cultural realities.>
Described in the article is the territorial distribution of the area of cultivated hops and hop production by the countries of the world, including the development and the grounds for their ...distribution. In the monitored period, the world area of cultivated hops decreased significantly, by more than a quarter. However, world hop production has grown little due to a substantial increase in hop yields. The area of cultivated hops and hop production are currently highly concentrated in the nine main hop producing countries. Roughly two thirds of the current area and three quarters of current production worldwide is attributable to the USA and Germany. Production increased in New Zealand, the USA, and to a lesser extent in Germany and Poland, while Australia, Czechia, Slovenia and especially China and the United Kingdom reduced production. Hop growing is very important for the agriculture of Germany, Czechia, and in particular Slovenia. These countries have the highest values of monitored hop indicators per capita, including hop export. The development of hop production in the coming years will depend on the introduction of new high-yielding hop varieties and enlargement or reduction of the area of cultivated hops in connection with hop price changes, profitability of hop growing and demand of breweries.
In this paper, we construct a realization problems involving connected outer-hop independent hop domination and we determine its connections with other known parameters in graph theory. In ...particular, given two positive integers a and b with 2 ≤ a ≤ b are realizable as the connected hop domination, connected outer-hop independent hop domination, and connected outer-independent hop domination numbers, respectively, of a connected graph. In addition, we characterize the connected outer-hop independent hop dominating sets in some families of graphs, join and corona of two graphs, and we use these results to derive formulas for the parameters of these graphs.
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