Atropisomeric alpha -oxoamides were synthesized and employed for intramolecular Paterno-Buechi reaction leading to very high enantio- and diastereoselectivity in the bicyclic oxetane photoproduct. A ...reversal of product selectivity was observed in solution and in the solid-state.
"Selectivity" is generally thought to be a key feature of probe molecules that are used to detect proteins, while a novel method for protein detection utilizing the "cross-reactivity" of molecule ...libraries has been proposed, called Cross-reactive Optical Fingerprinting (COF). In this paper, we summarize the principle and examples of COF for protein identification, followed by the introduction of our approaches to construct COF using polyion complexes (PICs) between enzymes and ionic polymers. In this approach, PICs with various characteristics were used to obtain unique optical fingerprints of changes in enzyme activity for analyte proteins. Statistical analysis of the obtained fingerprints has enabled the identification of human plasma proteins and albumin homologues. In addition, we have recently proposed "secretome fingerprinting" based on discriminating compositions of proteins secreted from cultured cells. This system has successfully allowed markerless and noninvasive identification of cancer cell types and lineages of stem cell differentiation.
Qi Zhang
Angewandte Chemie International Edition,
March 6, 2023, Letnik:
62, Številka:
11
Journal Article
Recenzirano
Odprti dostop
“My long‐term goal is to build supramolecular catalysts that are comparable to natural enzymes in terms of selectivity and efficiency … I'm always in a good mood when I watch the fish in my aquarium ...tanks …” Find out more about Qi Zhang in his Introducing … Profile.
Currently, thermal treatments are used extensively to convert millions of tons of biomass and municipal solid waste into energy products. Although biogas represents ∼50% of these energy products, ...usually disposed due to the difficulty to extract CH4 and H2 (main flammable compounds) from their complex composition contaminated by CO2, N2, etc. Recently, Polyethersulfone (PES) membranes have been employed for that purpose as an effective and cheap technology, however, their permeation properties under higher pressure and temperature are still undefined. Within this context, this research aims to study the influence of high temperatures and pressure on CO2/N2, CO2/H2 and CO2/CH4 selectivity performance of PES membranes and their potential applications in biogas upgrading systems. The experiments were started with preparation of the PES membranes using phase inversion methods, then observing their morphology, physical, chemical, thermal, and mechanical behaviors using SEM, XRD, FTIR, TGA, and universal testing machine. Consecutively, the initial gas separation experiments using CO2 gas were conducted to determine the maximum pressure and temperatures that the synthesized PES membranes can withstand without being damaged or thermally degraded. Based on the results of initial experiments, CO2/CH4, CO2/N2, and CO2/CH4 selectivity of the PES membranes was measured up to 60 °C and 6 bar (absolute pressure) using a set-up built especially for that purpose. Also, the effect of separation temperature and pressure on the separation mechanism were studied. The results revealed that the lowest pressure (1 bar) and the highest temperature (60 °C) can help to achieve the maximum selectivity performance for CO2/N2 (0.91), CO2/H2 (1.25), and CO2/CH4 (3.07), with improvement of 9, 20, and 17%, respectively. In addition, permeability of CO2 > N2 > H2 > CH4 increased by 13.2% (CO2), 15.1% (N2), 11% (H2), and 4.6% (CH4) at the same temperature. Based on that, pressure and temperature are considered as key factors that can be used to enhance the gas permeation and to control their pore shape. Also, PES membranes can be classified as a promising emerging technology for biogas upgrading with high selectivity, especially at high separation temperatures and low pressure.
•CNTs/PES and Graphene/PES membranes were prepared using doctor-blade.•Mechanical properties of the membranes were measured.•A nonlinear uniaxial model was built to simulate the mechanical performance.•The mechanical properties were reduced up to 26% for CNTs and 57% for GA.•The model is valid for deducing the uniaxial curves with deviation (0.164-0.715% ).
A critical overview of the theory of the chirality‐induced spin selectivity (CISS) effect, that is, phenomena in which the chirality of molecular species imparts significant spin selectivity to ...various electron processes, is provided. Based on discussions in a recently held workshop, and further work published since, the status of CISS effects—in electron transmission, electron transport, and chemical reactions—is reviewed. For each, a detailed discussion of the state‐of‐the‐art in theoretical understanding is provided and remaining challenges and research opportunities are identified.
Chirality‐induced spin selectivity (CISS), namely phenomena in which the chirality of molecular species imparts spin selectivity to various electron processes, has long defied a comprehensive theoretical explanation. Here, the status of CISS in electron transmission, electron transport, and chemical reactions is reviewed. For each, the state‐of‐the‐art in theoretical understanding is discussed and remaining challenges are identified.
This paper presents a design of dual-band bandpass filter with good stopband performance and high selectivity at the edges of passband by using interdigital embedded open loop triangular resonator ...structure loaded with stubs. The structure is less complex and easy to fabricate since no via or defected ground structure is used. Coupled stubs are loaded to the resonating structure to improve the stopband performance of proposed filter. Interdigital structure is embedded to the resonating structure loaded with stubs to improve second passband and stopband performance of proposed filter by realizing inter-stage coupling of interdigital capacitor in the resonator. A dual band BPF is designed for various applications in microwave communication systems at 5.6 and 13.7 GHz. The pass bands can be conveniently tuned to desired frequencies by controlling the corresponding resonator dimensions. The design topology and performance of the proposed filter is validated by electromagnetic simulator Agilent ADS. The measured results agree well with the simulated results.
A novel oxidative cascade cyclization of α‐(β‐amino)propenoyl‐alkylamides mediated by phenyl iodine (III) bis(trifluoroacetate) (PIFA) and 2,2,6,6‐tetramethyl piperidin‐1‐oxyl (TEMPO) has been ...described. This unprecedented transformation features mild reaction conditions, simple execution, high chemo‐ and regio‐selectivity, and thereby provides a facile and efficient protocol for the synthesis of polysubstituted 3,7‐dihydro‐ oxazolo4,5‐cpyridine‐2,4,6‐(5 H)‐triones.
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