At present, most of the university's conditions and teaching equipment have greater room for improvement, especially the management and teaching mechanism of computer laboratory need further ...improvement and breakthrough. Due to the rapid update speed of computer information technology related equipment, the update speed of university related equipment can not meet the needs of experimental education. Based on this, this paper first analyzes the application and development status of server virtualization technology, then studies the specific application of server virtualization technology in computer laboratory, and finally gives the application design strategy of server virtualization technology in computer laboratory.
Computing systems have been focused on performance improvements, driven by the demand of user applications in past few decades, particularly from 1990 to 2010. However, due to their ever-increasing ...energy demand which causes large energy bills and CO2 emissions, over the past six years the focus has shifted towards energy-performance aware. The average energy consumption of servers is increasing continuously; and several researchers suggest, if this trend continues further, the cost of energy consumed by a server during its lifetime will exceed the hardware costs. The energy consumption problem is even greater for large-scale infrastructures, such as clusters, grids and clouds, which consist of several thousand heterogeneous servers. Efforts are continuously made to minimize the energy consumption of these systems, but the interest of people in computational services and popularity of smart devices make it a difficult task. In this paper, we discuss the energy consumption of ICT equipment, and present a taxonomy of energy and performance efficient techniques for large computing systems covering clusters, grids and clouds (datacenters). We discuss both energy and performance efficiency, which makes this survey different from those already published in the literature. Key research papers are surveyed and mapped onto taxonomies to characterise and identify outstanding and key issues for further research. We discuss several state-of-the-art resource management techniques, reported in the literature, that claim significant improvement in the energy efficiency and performance of ICT equipment and large-scale computing systems such as datacenters, and identify a few open challenges.
•In clouds, energy aware scheduling techniques lead to significantly greater economies than consolidation techniques•In private clusters, switching off idle resources are more energy efficient than DPM methods, but, in clouds, performance is adversely affected due to fluctuated demand•In heterogeneous clouds, similar applications perform differently on similar CPU models, and, variations in runtime mean variations in cost and energy use•In clouds, due to resource heterogeneity, VM migrations affect energy use and the workload performance in terms of runtime (hence users cost)
Abstract
Due to the increasing amount of publicly available protein structures searching, enriching and investigating these data still poses a challenging task. The ProteinsPlus web service ...(https://proteins.plus) offers a broad range of tools addressing these challenges. The web interface to the tool collection focusing on protein–ligand interactions has been geared towards easy and intuitive access to a large variety of functionality for life scientists. Since our last publication, the ProteinsPlus web service has been extended by additional services as well as it has undergone substantial infrastructural improvements. A keyword search functionality was added on the start page of ProteinsPlus enabling users to work on structures without knowing their PDB code. The tool collection has been augmented by three tools: StructureProfiler validates ligands and active sites using selection criteria of well-established protein–ligand benchmark data sets, WarPP places water molecules in the ligand binding sites of a protein, and METALizer calculates, predicts and scores coordination geometries of metal ions based on surrounding complex atoms. Additionally, all tools provided by ProteinsPlus are available through a REST service enabling the automated integration in structure processing and modeling pipelines.
With the development of the Internet, the company network architecture is also undergoing profound changes, and the boundaries between the original internal network and external network are becoming ...increasingly blurred with the emergence of cloud services. More and more company businesses are deployed on the cloud server, which increases the risk of data exchange between the cloud server and the intranet. An implementation method of zero-trust architecture is proposed in this paper to apply to this scenario. The method can ensure safe and reliable data exchange when the external application server accesses the internal network, effectively protect network communication and business access while not affecting the original internal network protection measures, and make the company network safer and controllable.
In recent years, with the development of our country, higher requirements are put forward for the power supply. Electric power enterprises want to improve their comprehensive strength, but also in ...order to adapt to the development of the times, it is necessary to carry out information construction. However, the traditional physical server has many shortcomings and shortcomings in the enterprise information construction. Therefore, this paper puts forward the application research of server virtualization technology in power information construction. This paper compares and analyzes the resources needed by physical server and virtual server, and points out that virtual server have obvious advantages of high information security, low energy consumption, high utilization rate and low maintenance cost. In order to make the virtual server successfully applied in the information construction of electric power enterprises, this paper puts forward the operation guidance standard of server virtualization implementation process, and emphasizes that the integration of server resources should be done well in the process of information construction. In order to ensure the security of server virtualization process, this paper lists the detailed security measures of server virtualization. According to the operation of the above steps, the power enterprise can complete the information construction work better through the virtualization of the server. It is considered that the use of virtual server in enterprise information construction is a big trend, which conforms to the development of the times and improves the utilization rate of resources.
The Interactive Tree Of Life (https://itol.embl.de) is an online tool for the display, manipulation and annotation of phylogenetic and other trees. It is freely available and open to everyone. The ...current version introduces four new dataset types, together with numerous new features. Annotation options have been expanded and new control options added for many display elements. An interactive spreadsheet-like editor has been implemented, providing dataset creation and editing directly in the web interface. Font support has been rewritten with full support for UTF-8 character encoding throughout the user interface. Google Web Fonts are now fully supported in the tree text labels. iTOL v4 is the first tool which supports direct visualization of Qiime 2 trees and associated annotations. The user account system has been streamlined and expanded with new navigation options, and currently handles >700 000 trees from more than 40 000 individual users. Full batch access has been implemented allowing programmatic upload and export of trees and annotations.
Abstract
Gene set enrichment analysis has become one of the most frequently used applications in molecular biology research. Originally developed for gene sets, the same statistical principles are ...now available for all omics types. In 2016, we published the miRNA enrichment analysis and annotation tool (miEAA) for human precursor and mature miRNAs. Here, we present miEAA 2.0, supporting miRNA input from ten frequently investigated organisms. To facilitate inclusion of miEAA in workflow systems, we implemented an Application Programming Interface (API). Users can perform miRNA set enrichment analysis using either the web-interface, a dedicated Python package, or custom remote clients. Moreover, the number of category sets was raised by an order of magnitude. We implemented novel categories like annotation confidence level or localisation in biological compartments. In combination with the miRBase miRNA-version and miRNA-to-precursor converters, miEAA supports research settings where older releases of miRBase are in use. The web server also offers novel comprehensive visualizations such as heatmaps and running sum curves with background distributions. We demonstrate the new features with case studies for human kidney cancer, a biomarker study on Parkinson’s disease from the PPMI cohort, and a mouse model for breast cancer. The tool is freely accessible at: https://www.ccb.uni-saarland.de/mieaa2.
WebGestalt is a popular tool for the interpretation of gene lists derived from large scale -omics studies. In the 2019 update, WebGestalt supports 12 organisms, 342 gene identifiers and 155 175 ...functional categories, as well as user-uploaded functional databases. To address the growing and unique need for phosphoproteomics data interpretation, we have implemented phosphosite set analysis to identify important kinases from phosphoproteomics data. We have completely redesigned result visualizations and user interfaces to improve user-friendliness and to provide multiple types of interactive and publication-ready figures. To facilitate comprehension of the enrichment results, we have implemented two methods to reduce redundancy between enriched gene sets. We introduced a web API for other applications to get data programmatically from the WebGestalt server or pass data to WebGestalt for analysis. We also wrapped the core computation into an R package called WebGestaltR for users to perform analysis locally or in third party workflows. WebGestalt can be freely accessed at http://www.webgestalt.org.
AN OPEN SOURCE MAIL SERVER MIGRATION EXPERIENCE: IREDMAIL Azginoglu, N.
International archives of the photogrammetry, remote sensing and spatial information sciences.,
11/2020, Letnik:
XLIV-4/W3-2020
Journal Article, Conference Proceeding
Recenzirano
Odprti dostop
Servers are systems that set up to run for years, but it may be necessary to migrate to a new, better server when they have completed their lifetime or become inadequate. In this study, the ...open-source iRedMail e-mail server has been successfully migrated to another high-capacity physical server which uses an open-source CentOS operation system. Migration is a process that every step has to be very well planned. However, although planning is well done, unexpected errors may occur. For this reason, it is also essential to choose migration time. The experience gained as a result of the study is a guide for the new ones.
Abstract
SNPnexus is a web-based annotation tool for the analysis and interpretation of both known and novel sequencing variations. Since its last release, SNPnexus has received continual updates to ...expand the range and depth of annotations provided. SNPnexus has undergone a complete overhaul of the underlying infrastructure to accommodate faster computational times. The scope for data annotation has been substantially expanded to enhance biological interpretations of queried variants. This includes the addition of pathway analysis for the identification of enriched biological pathways and molecular processes. We have further expanded the range of user directed annotation fields available for the study of cancer sequencing data. These new additions facilitate investigations into cancer driver variants and targetable molecular alterations within input datasets. New user directed filtering options have been coupled with the addition of interactive graphical and visualization tools. These improvements streamline the analysis of variants derived from large sequencing datasets for the identification of biologically and clinically significant subsets in the data. SNPnexus is the most comprehensible web-based application currently available and these new set of updates ensures that it remains a state-of-the-art tool for researchers. SNPnexus is freely available at https://www.snp-nexus.org.
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