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  • Deklica z neodzivno kronično vnetno črevesno boleznijo - prvo poročilo o zdravljenju otroka z infliximabom v Sloveniji = A girl with a refractory chronic inflammatory bowel disease - first report of the treatment of a child with infliximab in Slovenia
    Brecelj, Jernej ...
    Infliximab is anti tumour necrosis factor-alpha (TNF-alpha) monoclonal antibody. In the field of gastroenterology it is indicated for the treatment of patients with medically refractory as well as ... fistulizing Crohn disease. The limitations of its use in the paediatric population are due to the possibility of serious side effects and unknown long-term consequences. We present a case report of the first treatment of refractory inflammatory bowel disease with infliximab in a child in our center. The treatment in a ten yearsold girl was uneventful. The clinical response was visible in a few days.Gradually we discontinued the corticosteroid therapy. She has maintained remission for seventeen weeks after the infusion of infliximab. We discuss theexperiences of other medical centers in comparison to our treatment course.
    Vir: Slovenska pediatrija : revija Združenja pediatrov Slovenije in Združenja specialistov šolske in visokošolske medicine Slovenije. - ISSN 1318-4423 (Letn. 10, št. 3, 2003, str. 169-172)
    Vrsta gradiva - članek, sestavni del
    Leto - 2003
    Jezik - slovenski
    COBISS.SI-ID - 17246169

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