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  • Optimization of UDP-N-acetylmuramic acid synthesis
    Humljan, Jan ...
    UDP-N-acetylmuramic acid (UDP-MurNAc) is a substrate of MurC, an important enzyme in the intracellular pathway of bacterial peptidoglycan biosynthesis. Various approaches towards preparation of ... UDP-MurNAc have been published but these synthetic preparations were shown to include many problematic steps. An optimization study with the focus on muramyl phosphate and UMP-morpholidate coupling was performed, resulting in a synthetic procedure enabling robust andeasily reproducible production on a multi-gram scale.
    Vir: Pharmazie. - ISSN 0031-7144 (Vol. 63, no. 2, 2008, str. 102-106)
    Vrsta gradiva - članek, sestavni del
    Leto - 2008
    Jezik - angleški
    COBISS.SI-ID - 2248817

vir: Pharmazie. - ISSN 0031-7144 (Vol. 63, no. 2, 2008, str. 102-106)

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