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  • Rezultati imunoterapije na strup insektov
    Kuhar, Marijana ; Puntarec, Irena ; Porenta-Bešić, Vlasta
    Background: Allergic reaction to stinging insects is one of the more dramatic allergic diseases. The preventiv etreatment prsently available is immunotherapy. The aim of this study was to analyse ... results of immunotherapy in our patients. Materials and methods: We retrospectively analysed data from 128 children, who had undergone Hymenoptera venom rush immunotherapy because of an allergic reaction after a bee (81 patients) or wasp (47 patients) sting at the Paediatric University Hospital during the period from 1985 to 1996. We were interested in the decrease of specific serum IgE antibodiy values after 5yearsć immunotherapy in comparision with initial values, and levels of venom specific IgG antibodies after 5 years of immunotherapy, adverse effects duringimmunotherapy and outcome after accidental subsequent field re-sting. ResultsČ We found a decrease in specific serum IgE antibodies in 70.4% patients in bee venom immunotherapy and 12.7% patients on wasp venom therapy. Levels of venom specific IgG antidobies were sufficient in 66.6% patients on bee venom immunotherapy and 61.7% patients on wasp venom immunotherapyafter 5 years of treatment. 34.6% of patients on bee venom immunotherapy and 29.8% of patients on waslp venom immunotherapy had adverse effects, most of which were local reactions. 66.6% of patients on bee venom immunotherapy and 55.3% of patients on wasp venom immunotherapy were re-stung. 92% showed no reaction or only a local one. Conclusion: Our results showed, that immunotherapy was very successful with only mild reactions after field re-sting during immunotherapy,and rare adverse effects. Levels of specific IgE serum antibodies and venom specific IgG antibodies in our patients were of low valuein predicting the effect of immunotherapy.
    Vir: Slovenska pediatrija : revija Združenja pediatrov Slovenije in Združenja specialistov šolske in visokošolske medicine Slovenije. - ISSN 1318-4423 (Letn. 5, suppl. 2, str. 108-111)
    Vrsta gradiva - prispevek na konferenci
    Leto - 1998
    Jezik - slovenski
    COBISS.SI-ID - 79657472

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