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  • Preliminary report: nitroglycerin patch for tocolysis in threatened preterm labour = Preliminarno poročilo: nitroglicerinski obliž za tokolizo pri grozečem prezgodnjem porodu
    Rebolj Stare, Marija ...
    Background. Prematurity is the main cause of perinatal morbidity and mortalityin Slovenia as well as elsewhere in the world. In threatening pretermlabour worldwide is tried to prolong pregnancy with ... tocolysis for at least 24-48 hours, but it would be desirable to postpone the delivery to 36 6/7 weeks of gestation. The purpose of this prospective observational preliminar study was to estimate the efficiency of nitroglycerin patch as a tocolytic agent, its subjective side effects with mothers and to compare the results with those of ritodrine and magnesium sulfate in our Department of Obstetrics and Gynaecology. Methods. Thirty-one pregnant women, who in certaintime fulfilled certain criteria, entered the study. They were divided into three groups regarding the tocolytic agent used. Selection of the tocolytic agent was not accidental. We observed the patients from the beginning of tocolysis until the delivery. The achieved period of prolongation, gestational age at birth, birth weight. Apgar score at the firstand fifth minute, reappearance of threatening preterm labour signs, proportion of deliveries after 36 6/7 weeks of pregnancy ans side effects werestatistically evaluated. Results. Significant difference was found among groups with singletons regarding the number of days, for which the pregnancy was extended. This number was the highest in the nitroglycerin patch group with 9.3 more days compared to magnesium sulfate group and 40.6 more days compared to the ritodrine group. Nitroglycerine patch is more effective as magnesium sulfate or ritodrine. In these three groups, significant difference was found when comparing gestational ages at birth. (Abstract truncated at 2000 characters).
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 68, št. 3, marec 1999, str. 145-150)
    Vrsta gradiva - članek, sestavni del
    Leto - 1999
    Jezik - angleški
    COBISS.SI-ID - 9929945

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