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The effect of peroral calcitriol in small doses on mild secondary hyperparathyroidism in patients on hemodialysisPečovnik-Balon, BredaOur prospective 1-year study comprises 93 patients of both sexes, various ages and various dialysis duration. Among them, 31 patients with a concentration of Ca in blood under 2.7 mmol/l, a ... concentration of P under 1.8 mmol/l and a concentration of PTHi over 65 pg/ml (group 0) received calcitriol 0.25 microgramx418p4The control group consisted of patients not receiving calcitriol and having normal Ca and P metabolism (group 1). The rest of the patients had a concentration of P over 1.8 mmol/l and could not be given calcitriol. A comparison of the dynamics of average plasmic concentrations of Ca, P, AP, PTHi and X-ray changes in group 0 and 1 at the beginning of the investigation and 1 year later was carried out. At the termination of the 1-year treatment, when compared to the initial state, a statistically significant increase in the concentration of Ca (p less th. 0.005) and in the concentration of P (p less th. 0.005) was noted in group 0. The average concentration of PTHi decreased to the desired level, the X-ray changes characteristic of secondary hyperparathyroidism progressed more slowly in group 0.Vir: American Journal of Nephrology. - ISSN 0250-8095 (Let. 15, št. 5, 1995, str. 401-406)Vrsta gradiva - članek, sestavni delLeto - 1995Jezik - angleškiCOBISS.SI-ID - 4687833
Avtor
Pečovnik-Balon, Breda
Teme
Calcitriol |
Therapeutic use |
Hemodialysis |
Adverse effects |
Hyperparathyroidism |
Drug therapy |
Administration, oral |
Adult |
Aged |
Alkaline phosphatase |
Blood |
Calcitriol |
Administration and dosage |
Calcium |
Blood |
Hyperparathyroidism |
Blood |
Etiology |
Middle age |
Parathyroid hormones |
Blood |
Phosphates |
Blood |
Prospective studies
Vnos na polico
Trajna povezava
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