To objectively evaluate the most common forms of mind-body exercise (MBE) (tai chi, yoga, qigong) on cognitive function among people with mild cognitive impairment (MCI). We searched 6 electronic databases (Scopus, PubMed, PsycINFO, WanFang, Web of Science, CNKI) from inception until September 2018. Nine randomized controlled trials and 3 nonrandomized controlled trials were included for meta-analysis. Two researchers independently performed the literature searches, study selection, data extraction, and methodological quality assessment using the revised Physiotherapy Evidence Database (PEDro) scale. The pooled effect size (standardized mean difference SMD) was calculated while random-effect model was selected. Overall results of the meta-analysis (N=1298 people with MCI) indicated that MBE significantly improved attention (SMD=0.39, 95% confidence interval CI 0.07-0.71, P=.02, I =31.6%, n=245), short-term memory (SMD=0.74, 95% CI 0.57-0.90, P<.001, I =0%, n=861), executive function (SMD=-0.42, 95% CI -0.63 to -0.21, P<.001, I =38.54%, n=701), visual-spatial/executive function (SMD=0.35, 95% CI 0.07-0.64, P<.05, I =0%, n=285), and global cognitive function (SMD=0.36, 95% CI 0.2-0.52, P<.001, I =15.12%, n=902). However, the significant positive effect on cognitive processing speed was not observed following MBE interventions (SMD=0.31, 95% CI -0.01 to 0.63, P=.054, I =28.66%, n=233). Study findings of this meta-analysis suggest that MBE have the potential to improve various cognitive functions in people with MCI.