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  • Pozharski, Edwin

    Methods in molecular biology (Clifton, N.J.), 01/2017, Letnik: 1522
    Journal Article

    Lipoplex preparations are heterogeneous mixtures of lipoplex particles of different structure. Because these structures determine the efficiency of genetic material delivery, it is important to characterize the distribution of particles of different types in lipoplex preparations with good statistics. We describe the application of flow fluorometry which allow producing such distributions (in terms of lipoplex particle size and composition) within minutes using basic flow cytometer (Pozharski and MacDonald, Anal Biochem 341:230-240, 2005).