E-viri
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Hansmann, M L; Gödde-Salz, E; Hui, P K; Müller-Hermelink, H K; Lennert, K
Cancer genetics and cytogenetics, 04/1986, Letnik: 21, Številka: 4Journal Article
Cytogenetic studies were performed in a case of progressively transformed germinal centers (PTGC), and in a case of nodular paragranuloma (NP; Hodgkin's disease with lymphocytic predominance, nodular type). No cytogenetic abnormalities were detected in PTGC. Chromosomal aberrations (hyperdiploidy, 6q-, +21, and several unidentified markers) were found in NP. The results support the proposal that PTGC are reactive in nature and NP is a neoplasm. Chromosomal analysis could provide practical diagnostic aids in the differential diagnosis of PTGC and NP.
