The article discusses the findings of a study to evaluate and update the 2012 recommendations by the U.S. Preventive Services Task Force (USPSTF) on screening for cervical cancer, which revealed that the USPSTF recommends screening for cervical cancer every 3 years with cervical cytology alone in women aged 21 to 29 years, and recommends screening every 3 years alone with cervical cytology along, every 5 years with hrHPV testing alone, or every 5 years with hrHPV testing in combination with cytology (contesting) in women aged 30-65 years. The need to make the tools available to the populations that bear the greatest disease burden from cervical cancer such as poor women, women from communities of color, and other women with compromised access to timely and effective care is highlighted.