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Belančić, Andrej; Hlača, Nika; Peternel, Sandra; Golčić, Marin; Prpić‐Massari, Larisa; Vlahović‐Palčevski, Vera
British journal of clinical pharmacology, August 2024, Letnik: 90, Številka: 8Journal Article
We present a 70‐year‐old female patient diagnosed with epidermal growth factor receptor‐mutated metastatic non‐small cell lung cancer (T4N2M1a), who developed afatinib‐induced toxic epidermal necrolysis (TEN). We have also performed a PubMed/Medline literature review to detect other possible cases of TEN/Stevens–Johnson syndrome associated with afatinib treatment and found only 5 other cases reported. To our best knowledge, this is the first case of afatinib‐induced TEN successfully treated with cyclosporine.
