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Zegarra-Lizana, Paolo A; Ramos-Orosco, Elizabeth J; Guarnizo-Poma, Mirella; Pantoja-Torres, Betzi; Paico-Palacios, Socorro; Del Carmen Ranilla-Seguin, Vitalia; Lazaro-Alcantara, Herbert; Benites-Zapata, Vicente A
Diabetes & metabolic syndrome clinical research & reviews, 2019 Sep - Oct, 2019-09-00, 20190901, Letnik: 13, Številka: 5Journal Article
To evaluate the association between elevated body fat percent (BF%) and the prevalence of insulin resistance (IR) in the adult population with body mass index (BMI) in the normal values. We carry out an analytical cross-sectional study. The participants attended outpatient from 2012 to 2016 in a private clinic in Lima-Peru between 18 and 60 years with a BMI between 19 and 24.9/Kg/m2. We defined elevated BF% if the values were greater than 25% in men and 30% in women and IR with a cut-off point of HOMA-IR based in the 75th percentile. We performed a generalized linear model from family Poisson (crude and adjusted) with robust standard errors to evaluate the association between BF% and the IR. We reported as association measure the prevalence ratio (PR) with their respective 95% confidence intervals (CI). We included 284 participants, the average age was 33.77 ± 10.86 (SD) years and the percentage of women was 88.1%. The prevalence of elevated BF% was 71.13% and the prevalence of IR was 25%. We found an association between the elevated BF% and IR, PR = 3.17; 95% CI: 1.46-6.91. Body fat percentage seems to be a good indicator of IR in patients with normal BMI and without endocrine comorbidities. Longitudinal prospective studies are recommended to corroborate our findings.
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