BACKGROUNDInability to cross the lesion with a balloon is the second-most common cause of technical failure, with the most common cause being the inability to cross with the wire. We propose a new, effective method for treating balloon-uncrossable lesions, called the "deep-wire crossing" (DWC) technique. OBJECTIVESThe aim of this study was to evaluate the procedural outcomes of the DWC technique for treating balloon-uncrossable lesions. METHODSFrom 2017 to 2018, a total of 95 patients with balloon-uncrossable lesions were treated using the DWC technique at our center. Procedural and in-hospital outcomes were assessed. RESULTSIn most cases, the target vessel was the left circumflex (46.3%), followed by the right coronary artery (31.6%) and left anterior descending (22.1%). According to the American College of Cardiology/American Heart Association classification, 41% of lesions were classified as type C, 40% as type B2, and 18.9% as type B1. Chronic total occlusion occurred in 24 patients (25.3%). Overall technical success was achieved in 84 patients (88.4%). Successful DWC technique was achieved in 74 patients (77.9%). In-hospital major adverse cardiac event rate was 3.2%. Coronary perforation required pericardiocentesis in only 1 patient. Periprocedural myocardial infarction occurred in 1 patient and was managed conservatively; urgent revascularization was required for 1 patient. CONCLUSIONOur experience with the DWC technique demonstrated that it can be a viable option for treating balloon- uncrossable lesions, and operators should become familiar with it.