GLC determination of ticrynafen and its metabolites in urine, serum, and plasma of humans and animals

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GLC determination of ticrynafen and its metabolites in urine, serum, and plasma of humans and animals

Hwang, B; Konicki, G; Dewey, R; Miao, C

Journal of pharmaceutical sciences, August 1978, Letnik: 67, Številka: 8

Journal Article

A sensitive GLC assay for ticrynafen, a diuretic agent with uricosuric properties, and its two metabolites in urine, serum, and plasma is described. The method employs methylation of carboxylic acid groups and trimethylsilyation of the hydroxyl group on one metabolite that cannot otherwise be separated readily from ticrynafen as a simple methyl ester. Urinary output and serum or plasma levels of ticrynafen and its two metabolites were measured in specimens from human volunteers receiving one 250-mg tablet.

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Hwang, B | Konicki, G | Dewey, R | Miao, C

Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.

Leto	Faktor vpliva		Izdaja		Kategorija		Razvrstitev
Leto	JCR	SNIP	JCR	SNIP	JCR	SNIP	JCR	SNIP

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