In this study, the rheological behavior of TiO2/ZnO/EG nanofluid at temperature range of 25 °C to 50 °C has been experimentally investigated. The steady and homogeneous suspensions, in volume fractions of 0.1% to 1.5%, have been prepared with volume composition of 50% ZnO nanoparticles and 50% TiO2nanoparticles in a specified amount of EG. The viscosities of sample nanofluid have been measured in different shear rates of 6.12 S−1 to 61.2 S−1. The results of viscosity measurement showed that, TiO2/ZnO/EG nanofluid has Newtonian behavior in volume fractions of 0.1%, 0.3% and 0.5% and in all of the considered temperatures and by increasing volume fraction of nanoparticles, the viscosity of nanofluid enhances and also, by increasing the temperature, nanofluid viscosity reduces. While, the sample nanofluid in volume fractions of 1% and 1.5% have non-Newtonian behavior similar with power law model with power coefficient less than 1. For nanofluid samples in 1% and 1.5% volume fractions in all considered temperatures, the power law model coefficients have been calculated by curve-fitting with high accuracy The results indicated that, in general, by increasing volume fraction, the apparent viscosity enhances and by increasing the temperature, the apparent viscosity reduces. •Produce a new hybrid nanofluid composed of TiO2/ZnO/EG.•Evaluation of sample dynamic viscosity based on empirical results.•Non-Newtonian power law model with temperature and concentration.