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Melo, Adriana; de Sales Tavares, Jousilene; de Assis Costa, Marianny; Santana de Aguiar, Renato; Malinger, Gustavo; de Oliveira Melo, Fabiana; Balbino da‐Silva, Mariana; Luiz Fonseca Schamber‐Reis, Bruno; Gama, Gabriela; Tanuri, Amilcar; Chimelli, Leila; Oliveira‐Szejnfeld, Patricia; M. Ramos de Amorim, Melania
Prenatal diagnosis, December 2020, 2020-12-00, 20201201, Letnik: 40, Številka: 13Journal Article
Objective To describe obstetric and perinatal outcomes in cases of congenital Zika syndrome (CZS). Methods A dual prospective and retrospective cohort study involving 102 pairs of mothers and fetuses/children with CZS whose infection was confirmed by testing for the Zika virus in amniotic fluid, umbilical cord blood, and fragments from the placenta of the newborn infant (confirmed CZS), or by intrauterine imaging tests (neurosonography), and/or postnatal computed tomography (presumed CZS). Results Suspicion of CZS was investigated by ultrasonography during pregnancy in 52.9% of cases. The principal prenatal imaging findings were ventriculomegaly (43.1%) and microcephaly (42.2%). Median gestational age at delivery was 39 weeks, with 15.7% being premature. Mean head circumference at birth was 30.0 ± 2.3 cm, with 66% of cases being classified as having microcephaly. Arthrogryposis was found in 10 cases (9.8%). There were no fetal deaths; however, nine neonatal deaths were recorded, and three autopsies were performed. Conclusion Neonatal mortality was high, almost 10%. Regarding the abnormalities of CZS, microcephaly, although common, was not present in all cases and intracranial findings need to be taken into consideration for diagnosis. Therefore, ultrasound screening during pregnancy should be systematized and expanded in endemic zones.
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Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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