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Kriegelstein, Michal; Hroch, Miloš; Marek, Aleš
Journal of labelled compounds & radiopharmaceuticals, November 2021, 2021-11-00, 20211101, Letnik: 64, Številka: 13Journal Article
Convenient and straightforward synthesis of ibrutinib labeled by carbon‐13 isotope is reported. Isotopically labeled building block is introduced in the last step of reaction sequence affording sufficient isolated yield (7%) of 13C6‐ibrutinib calculated towards starting commercially available 13C6‐bromobenzene. Convenient and straightforward synthesis of 13C6‐ibrutinib is reported.
![Synthesis of [13C6]‐ibrutinib](http://api.summon.serialssolutions.com/2.0.0/image/issn/XR4PS5YY4K/0362-4803/medium "Synthesis of [13C6]‐ibrutinib")
