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  • Eflornithine plus Sulindac ...
    Burke, Carol A; Dekker, Evelien; Lynch, Patrick; Samadder, N. Jewel; Balaguer, Francesc; Hüneburg, Robert; Burn, John; Castells, Antoni; Gallinger, Steven; Lim, Ramona; Stoffel, Elena M; Gupta, Samir; Henderson, Alex; Kallenberg, Frank G; Kanth, Priyanka; Roos, Victorine H; Ginsberg, Gregory G; Sinicrope, Frank A; Strassburg, Christian P; Van Cutsem, Eric; Church, James; Lalloo, Fiona; Willingham, Field F; Wise, Paul E; Grady, William M; Ford, Molly; Weiss, Jennifer M; Gryfe, Robert; Rustgi, Anil K; Syngal, Sapna; Cohen, Alfred

    The New England journal of medicine, 09/2020, Letnik: 383, Številka: 11
    Journal Article

    In randomized trial involving 171 adults with familial adenomatous polyposis, the incidence of disease progression was not significantly lower with combination therapy with eflornithine (an inhibitor of ornithine decarboxylase) and sulindac (an NSAID) than with either drug alone.