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Harris, Isaac S; Brugge, Joan S
Nature (London), 11/2015, Letnik: 527, Številka: 7577Journal Article
In this issue, Piskounova et al.3 (page 186) shed light on the subject by showing that efficient spread of melanoma cells to distant sites in the body depends on their ability to overcome the cellular stress induced by reactive oxygen species (ROS) that are encountered as the cells move through the bloodstream and initiate new tumours. ROS have also been shown to promote the stabilization of factors that can drive tumour initiation and progression4.
