The objective was to quantify the effect of breed composition on sale price of steer and heifer calves sold through a single livestock video auction service from 2010 through 2016. Data were available from steer (29,103 lots) and heifer (18,955 lots) calves sold in 164 unique video auctions through one livestock video auction service. A multiple regression model using a backward selection procedure was developed for each calf sex to quantify effects of independent factors on sale price. A value of P < 0.05 was used to maintain a factor in the final model. Lots of calves were categorized into 1 of 6 breed groups: English and English-crossed, English–Continental crossed, Black Angus-sired calves out of dams with no Brahman influence, Red Angus-sired calves out of dams with no Brahman influence, Charolais-sired calves out of dams with no Brahman influence, and Brahman influenced. Breed description of steer and heifer calf lots affected sale price (P < 0.0001). Among heifers, Red Angus-sired calves had the greatest (P < 0.05) sale price ($173.88/45.36 kg of BW) compared with heifers of other breed groups. Among steers, Charolais-sired calves ($179.09/45.36 kg of BW) were similar (P = 0.19) in value to Red Angus-sired calves ($177.86/45.36 kg of BW) and greater (P < 0.05) than Black Angus-sired calves ($177.23/45.36 kg of BW). Sire breeds selected, buyer preferences, and marketing venues of both steer and heifer calves should be considered holistically by producers so maximal calf values are realized when sold.