E-viri
Recenzirano
Odprti dostop
-
Mahé, E.; Maccari, F.; Beauchet, A.; Lahfa, M.; Barthelemy, H.; Reguiaï, Z.; Beneton, N.; Estève, E.; Chaby, G.; Ruer-Mulard, M.; Steiner, H.-G.; Pauwels, C.; Avenel-Audran, M.; Goujon-Henry, C.; Descamps, V.; Begon, E.; Sigal, M.-L.
British journal of dermatology (1951), October 2013, Letnik: 169, Številka: 4Journal Article
Summary Background Psoriasis is associated with higher prevalences of cardiovascular and metabolic comorbidities in adults but the relationship of age at onset and those prevalences is unknown. Objective To evaluate whether the childhood onset of psoriasis (COP) is correlated with the frequency of cardiovascular and metabolic comorbidities in adulthood. Methods This noninterventional, cross‐sectional, multicentre study of adults with psoriasis was conducted in 29 dermatology centres in France. Data on sex, age at onset of psoriasis and its clinical characteristics, and cardiovascular risk factors, including weight, body mass index, waist circumference, dyslipidaemia, diabetes, hypertension, smoking, and personal/familial major adverse cardiovascular events (MACE) were systematically recorded. Results Two thousand two hundred and one patients with psoriasis (male: 56%; mean age: 49 years; 25% with COP) were included consecutively in the study. Univariate analysis showed that COP was associated with lower frequencies of obesity, high waist circumference, diabetes, dyslipidaemia, hypertension, familial cardiovascular disease, MACE and metabolic syndrome, but more frequent active smoking. Multivariate analysis retained age as being associated with frequency of cardiovascular and metabolic comorbidities, and sex with smoking, but not age at the onset of psoriasis. Psoriasis severity was associated with higher frequencies of obesity and psoriatic arthritis. Conclusion Our results showed that COP does not seem to be an additional risk factor for higher frequencies of cardiovascular and metabolic comorbidities during adulthood. What's already known about this topic? Psoriasis and its severity are associated with higher prevalence of cardiovascular and metabolic comorbidities in adults. Childhood onset of psoriasis is not associated with obesity in adulthood. What does this study add? Childhood onset of psoriasis is not associated with cardiovascular and metabolic comorbidities in adulthood. In France, as in most countries, psoriasis is associated with high frequencies of cardiovascular and metabolic comorbidities in adults.
Avtor
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.