In this introduction, we highlight the developments and transformations that have been put forward and situate our examination of Queer Asias within that context. We then turn to the contributions in this special issue, which collectively examine the intricate and imbricated flows of capital, power, intimacy, citizenship, sexual politics, and categories of gender and sexual (self-)identification in and across Japan, Taiwan, Indonesia, Hong Kong, the Philippines, and the United States. The articles in this special issue take up the following questions through an exploration of local genealogies of sexual practices, intimacies, and meanings in people’s everyday lives: What forms of categories, politics, and activism have gender and sexually diverse peoples across East and Southeast Asia embraced, constructed, and challenged in the 2010s through the early 2020s? What new theories have scholars developed and to what end? Whose politics are now being advocated and how might their activism contest older strategies and discourses?